Ancient horse genome oldest ever sequenced

2013 ◽  
Author(s):  
Sara Osman
Keyword(s):  
Horse Genome

Identification of 21 781 equine microsatellites on the horse genome assembly 2.0

2010 ◽  
Vol 41 (2) ◽  
pp. 222-222 ◽  
Author(s):  
E. H. Mittmann ◽  
J. Wrede ◽  
J. Pook ◽  
O. Distl
Keyword(s):  
Genome Assembly ◽  
Horse Genome

scholarly journals Characterization of Equine Infectious Anemia Virus Integration in the Horse Genome

Viruses ◽  
2015 ◽  
Vol 7 (6) ◽  
pp. 3241-3260 ◽  
Author(s):  
Qiang Liu ◽  
Xue-Feng Wang ◽  
Jian Ma ◽  
Xi-Jun He ◽  
Xiao-Jun Wang ◽  
...  
Keyword(s):  
Equine Infectious Anemia Virus ◽  
Horse Genome ◽  
Equine Infectious Anemia ◽  
Anemia Virus ◽  
Virus Integration

The Horse Genome

2006 ◽  
pp. 97-110 ◽  
Author(s):  
B.P. Chowdhary ◽  
T. Raudsepp
Keyword(s):  
Horse Genome

Genetical and physical assignments of equine microsatellites—first integration of anchored markers in horse genome mapping

1997 ◽  
Vol 8 (4) ◽  
pp. 267-273 ◽  
Author(s):  
Matthew Breen ◽  
Gabriella Lindgren ◽  
Matthew M. Binns ◽  
Julianne Norman ◽  
Zlaka Irvin ◽  
...  
Keyword(s):  
Genome Mapping ◽  
Horse Genome

scholarly journals Characterisation of retroviruses in the horse genome and their transcriptional activity via transcriptome sequencing

Virology ◽  
2012 ◽  
Vol 433 (1) ◽  
pp. 55-63 ◽  
Author(s):  
Katherine Brown ◽  
Joanna Moreton ◽  
Sunir Malla ◽  
A. Aziz Aboobaker ◽  
Richard D. Emes ◽  
...  
Keyword(s):  
Transcriptome Sequencing ◽  
Transcriptional Activity ◽  
Horse Genome

scholarly journals Mapping the horse genome and its impact on equine genomics for identification of genes for monogenic and complex traits – a review

2007 ◽  
Vol 50 (1) ◽  
pp. 7-24
Author(s):  
D. Stübs ◽  
O. Distl
Keyword(s):  
Complex Traits ◽  
Gene Mutations ◽  
Hereditary Diseases ◽  
Multifactorial Diseases ◽  
Horse Genome ◽  
Genome Maps ◽  
Horse Breeding ◽  
And Performance ◽  
The Moment ◽  
Animal Genomes

Abstract. Since the beginning of investigation in the horse genome in the early nineties, there has been a great progress, especially during the last five years. At the beginning the exploration of monogenic hereditary diseases was one of the main aims, and the causal mutations of several diseases in the horse have been unravelled. The inheritance of coat colours has been explored very detailed, and there exist gene tests for different coat colours. Information about coat colours and inherited diseases is very important for the breeders and helps avoiding the appearance of lethal genetic factors or undesirable diseases. The most important achievements of horse genome analysis were well-developed linkage, radiation hybrid and cytogenetic genome maps including more than 2950 loci. These maps support comparative analysis of equine hereditary diseases. The present known gene mutations for five diseases in horses have human homologs. Studies on multifactorial diseases such as osteochondrosis and navicular bone disease and on fertility and temperament are underway. At the moment, the whole equine genome is sequenced as it has been done for the human genome and also for other animal genomes. Horse breeding will greatly benefit from identification of QTL for multifactorial traits and gene mutations for congenital anomalies, diseases and performance traits.

scholarly journals Evaluation of a new variant in the aggrecan gene potentially associated with chondrodysplastic dwarfism in Miniature horses

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Danilo Giorgi Abranches de Andrade ◽  
Roberta Martins Basso ◽  
Angelo José Magro ◽  
Renée Laufer-Amorim ◽  
Alexandre Secorun Borges ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Amino Acid ◽  
Amino Acid Substitution ◽  
Autosomal Recessive ◽  
Autosomal Recessive Disorder ◽  
Dwarf Phenotype ◽  
Horse Genome ◽  
Complex Interactions ◽  
New Variant ◽  
Exon 11

Abstract Chondrodysplastic dwarfism in Miniature horses is an autosomal recessive disorder previously associated with four mutations (D1, D2, D3*, and D4) in the aggrecan (ACAN) gene. The aim of this study was to identify additional variants in the candidate ACAN gene associated with chondrodysplastic dwarfism in Miniature horses. Fifteen dwarf Miniature horses were found to possess only one of the dwarfism-causing variants, and two possessed none of the variants. The ACAN exons (EquCab3.0) of seven dwarf Miniature horses were sequenced. A missense SNP in coding exon 11 (g.95271115A > T, c.6465A > T—RefSeq XM_005602799.2), which resulted in the amino acid substitution p.Leu2155Phe (RefSeq XP_005602856.2), was initially associated with the dwarf phenotype. The variant was tested and found present in 14 dwarf foals as well as one parent of each, and both parents of a dwarf possessing two copies. Genetic testing of 347 phenotypically normal Miniature horses demonstrated that none had more than one of the dwarf alleles or c.6465A > T. However, a study of large breeds revealed the presence of c.6465A > T, which was present in homozygosis in two Mangalarga Marchador horses. We suggest that c.6465A > T as a marker of disequilibrium or complex interactions in the Miniature horse genome could contribute to the associated dwarfism.

The Horse Genome Derby: racing from map to whole genome sequence

2008 ◽  
Vol 16 (1) ◽  
pp. 109-127 ◽  
Author(s):  
Bhanu P. Chowdhary ◽  
Terje Raudsepp
Keyword(s):  
Genome Sequence ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Horse Genome
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