scholarly journals Direct determination of haplotypes from single DNA molecules

2009 ◽  
Vol 6 (3) ◽  
pp. 199-201 ◽  
Author(s):  
Ming Xiao ◽  
Eunice Wan ◽  
Catherine Chu ◽  
Wen-Chi Hsueh ◽  
Yang Cao ◽  
...  
2007 ◽  
Vol 28 (9) ◽  
pp. 913-921 ◽  
Author(s):  
Ming Xiao ◽  
Matthew P. Gordon ◽  
Angie Phong ◽  
Connie Ha ◽  
Ting-Fung Chan ◽  
...  

2017 ◽  
Vol 5 (30) ◽  
pp. 7637-7643 ◽  
Author(s):  
M. Shaali ◽  
J. G. Woller ◽  
P. G. Johansson ◽  
J. K. Hannestad ◽  
L. de Battice ◽  
...  

Teflon AF acts as a negative e-beam resist, here utilized for immobilization of porphyrin-anchored single DNA molecules on nanopillars, and precise determination of individual label positions.


Author(s):  
Carlos Bustamante ◽  
Steven B. Smith

Understanding the mechanical properties of DNA such as their bending and torsional rigidity can provide a great deal of insight about the factors that determine the folding of DNA during the cell cycle. These quantities have been obtained from bulk experiments using light scattering, equilibrium sedimentation, DNA cyclization, etc. Determination of the elastic properties of DNA with these methods is indirect, via a theoretical framework relating the observable quantities to the elastic parameters of the molecules. Moreover, the results represent an ensemble average over all accessible configurations of the molecule, with small contribution from stretched un-likely states.We have carried a systematic study of the elastic properties of single DNA molecules. Single DNA molecules were chemically attached by one end to a glass surface and by their other end to a magnetic bead. Equilibrium positions of the beads are observed in an optical microscope while the beads are acted on by known magnetic and hydrodynamic forces.


1961 ◽  
Vol 41 (4) ◽  
pp. 380-384 ◽  
Author(s):  
Arthur F. Dratz ◽  
James C. Coberly
Keyword(s):  

2002 ◽  
Vol 721 ◽  
Author(s):  
Monica Sorescu

AbstractWe propose a two-lattice method for direct determination of the recoilless fraction using a single room-temperature transmission Mössbauer measurement. The method is first demonstrated for the case of iron and metallic glass two-foil system and is next generalized for the case of physical mixtures of two powders. We further apply this method to determine the recoilless fraction of hematite and magnetite particles. Finally, we provide direct measurement of the recoilless fraction in nanohematite and nanomagnetite with an average particle size of 19 nm.


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