NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice

Hideto Kojima; Mineko Fujimiya; Kazuhiro Matsumura; Patrick Younan; Hirotsugu Imaeda; Makiko Maeda; Lawrence Chan

doi:10.1038/nm867

NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice

Nature Medicine ◽

10.1038/nm867 ◽

2003 ◽

Vol 9 (5) ◽

pp. 596-603 ◽

Cited By ~ 322

Author(s):

Hideto Kojima ◽

Mineko Fujimiya ◽

Kazuhiro Matsumura ◽

Patrick Younan ◽

Hirotsugu Imaeda ◽

...

Keyword(s):

Gene Therapy ◽

Islet Neogenesis ◽

Diabetes In Mice

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Neurod/betacellulin gene therapy induces pancreatic islet neogenesis in the liver and reverses diabetes in mice

Gastroenterology ◽

10.1016/s0016-5085(03)80424-9 ◽

2003 ◽

Vol 124 (4) ◽

pp. A86

Author(s):

Mineko Fujimiya ◽

Hideto Kojima ◽

Tamio Nakahara ◽

Lawrence Chan

Keyword(s):

Gene Therapy ◽

Pancreatic Islet ◽

Islet Neogenesis ◽

Diabetes In Mice

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Faculty Opinions recommendation of NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1013139.189254 ◽

2003 ◽

Author(s):

Brendan Lee

Keyword(s):

Gene Therapy ◽

Islet Neogenesis ◽

Diabetes In Mice

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Adipocyte-derived stem cell-based gene therapy upon adipogenic differentiation on microcarriers attenuates type 1 diabetes in mice

Stem Cell Research & Therapy ◽

10.1186/s13287-019-1135-y ◽

2019 ◽

Vol 10 (1) ◽

Cited By ~ 5

Author(s):

Qing Fang ◽

Min Zhai ◽

Shan Wu ◽

Xiaogen Hu ◽

Zhan Hua ◽

...

Keyword(s):

Gene Therapy ◽

Type 1 Diabetes ◽

Stem Cell ◽

Adipogenic Differentiation ◽

Diabetes In Mice

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203. Insulin-Gene Therapy of Diabetes in Mice by Glucose-Regulated Helper-Dependent Adenoviral Vectors

Molecular Therapy ◽

10.1016/s1525-0016(16)40645-3 ◽

2003 ◽

Vol 7 (5) ◽

pp. S79-S80

Keyword(s):

Gene Therapy ◽

Adenoviral Vectors ◽

Insulin Gene ◽

Diabetes In Mice

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Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: an ex vivo gene therapy approach

Diabetologia ◽

10.1007/s00125-006-0509-8 ◽

2006 ◽

Vol 50 (1) ◽

pp. 121-130 ◽

Cited By ~ 29

Author(s):

A. Fodor ◽

C. Harel ◽

L. Fodor ◽

M. Armoni ◽

P. Salmon ◽

...

Keyword(s):

Gene Therapy ◽

Rat Liver ◽

Ex Vivo ◽

Liver Cells ◽

Therapy Approach ◽

Gene Therapy Approach ◽

Adult Rat ◽

Diabetes In Mice ◽

Rat Liver Cells ◽

Ex Vivo Gene Therapy

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39. Reversal of Diabetes by Inducing Islet Neogenesis Using Helper Dependent Adenovirus Mediated Gene Therapy

Molecular Therapy ◽

10.1016/j.ymthe.2004.05.062 ◽

2004 ◽

Vol 9 ◽

pp. S16-S17

Keyword(s):

Gene Therapy ◽

Islet Neogenesis

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Safe and low-dose but therapeutically effective adenovirus-mediated hepatocyte growth factor gene therapy for type 1 diabetes in mice

Life Sciences ◽

10.1016/j.lfs.2020.119014 ◽

2021 ◽

Vol 268 ◽

pp. 119014

Author(s):

Eriko Matsuda ◽

Yuki Obama ◽

Ken-ichiro Kosai

Keyword(s):

Gene Therapy ◽

Type 1 Diabetes ◽

Growth Factor ◽

Hepatocyte Growth Factor ◽

Low Dose ◽

Factor Gene ◽

Diabetes In Mice ◽

Growth Factor Gene ◽

Hepatocyte Growth

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Researchers Use Gene Therapy to Repair Inner-Ear Defects in Mice

ASHA Leader ◽

10.1044/leader.rib3.21022016.np ◽

2016 ◽

Vol 21 (2) ◽

Keyword(s):

Gene Therapy ◽

Inner Ear

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Cyclooxygenese-2 promoter can mittigate the lethal toxicity in HSV-TK based adenoviral suicide gene therapy of gastrointestinal cancers

Gastroenterology ◽

10.1016/s0016-5085(01)80051-2 ◽

2001 ◽

Vol 120 (5) ◽

pp. A10-A10

Author(s):

M YAMAMOTO ◽

R ALEMANY ◽

Y ADACHI ◽

W GRIZZLE ◽

D CURIEL

Keyword(s):

Gene Therapy ◽

Suicide Gene ◽

Suicide Gene Therapy ◽

Gastrointestinal Cancers ◽

Lethal Toxicity

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Antiangiogenic gene therapy delays growth of murine and human pancreatic adenocarcinoma in mice

Gastroenterology ◽

10.1016/s0016-5085(01)81737-6 ◽

2001 ◽

Vol 120 (5) ◽

pp. A349-A349

Author(s):

J TSENG ◽

F FARNEBO ◽

O KISKER ◽

C BECKER ◽

C KUO ◽

...

Keyword(s):

Gene Therapy ◽

Pancreatic Adenocarcinoma ◽

Human Pancreatic Adenocarcinoma

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