Peroxisome proliferator–activated receptor-δ attenuates colon carcinogenesis

Fred S Harman; Christopher J Nicol; Holly E Marin; Jerrold M Ward; Frank J Gonzalez; Jeffrey M Peters

doi:10.1038/nm1026

Peroxisome proliferator–activated receptor-δ attenuates colon carcinogenesis

Nature Medicine ◽

10.1038/nm1026 ◽

2004 ◽

Vol 10 (5) ◽

pp. 481-483 ◽

Cited By ~ 151

Author(s):

Fred S Harman ◽

Christopher J Nicol ◽

Holly E Marin ◽

Jerrold M Ward ◽

Frank J Gonzalez ◽

...

Keyword(s):

Colon Carcinogenesis ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor

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Decreased Toll-interacting protein and peroxisome proliferator-activated receptor γ are associated with increased expression of Toll-like receptors in colon carcinogenesis

Journal of Clinical Pathology ◽

10.1136/jclinpath-2011-200567 ◽

2012 ◽

Vol 65 (4) ◽

pp. 302-308 ◽

Cited By ~ 27

Author(s):

Pedro Pimentel-Nunes ◽

Nádia Gonçalves ◽

Inês Boal-Carvalho ◽

Luís Afonso ◽

Paula Lopes ◽

...

Keyword(s):

Colon Carcinogenesis ◽

Peroxisome Proliferator ◽

Toll Like Receptors ◽

Peroxisome Proliferator Activated Receptor ◽

Interacting Protein

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T2001 Inhibitory Effect of Embelin On Colon Carcinogenesis Is Peroxisome Proliferator-Activated Receptor γ (PPARγ)-Dependent

Gastroenterology ◽

10.1016/s0016-5085(09)62847-x ◽

2009 ◽

Vol 136 (5) ◽

pp. A-617-A-618

Author(s):

Yun Dai ◽

Liang Qiao ◽

Kwok Wah Chan ◽

Juan Ma ◽

Bing Zou ◽

...

Keyword(s):

Colon Carcinogenesis ◽

Inhibitory Effect ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor

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Peroxisome Proliferator-Activated Receptor-γ Contributes to the Inhibitory Effects of Embelin on Colon Carcinogenesis

Cancer Research ◽

10.1158/0008-5472.can-08-4754 ◽

2009 ◽

Vol 69 (11) ◽

pp. 4776-4783 ◽

Cited By ~ 52

Author(s):

Yun Dai ◽

Liang Qiao ◽

Kwok Wah Chan ◽

Mo Yang ◽

Jieyu Ye ◽

...

Keyword(s):

Colon Carcinogenesis ◽

Peroxisome Proliferator ◽

Inhibitory Effects ◽

Peroxisome Proliferator Activated Receptor

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Peroxisome proliferator-activated receptor γ ligands suppress colon carcinogenesis induced by azoxymethane in mice

Gastroenterology ◽

10.1053/gast.2003.50067 ◽

2003 ◽

Vol 124 (2) ◽

pp. 361-367 ◽

Cited By ~ 138

Author(s):

Emi Osawa ◽

Atsushi Nakajima ◽

Koichiro Wada ◽

Satoko Ishimine ◽

Nobutaka Fujisawa ◽

...

Keyword(s):

Colon Carcinogenesis ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor

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Peroxisome Proliferator-Activated Receptor γ (PPARγ) Suppresses Colonic Epithelial Cell Turnover and Colon Carcinogenesis Through Inhibition of the β-Catenin / T Cell Factor (TCF) Pathway

Journal of Pharmacological Sciences ◽

10.1254/jphs.fp0071766 ◽

2008 ◽

Vol 106 (4) ◽

pp. 627-638 ◽

Cited By ~ 18

Author(s):

Toshio Fujisawa ◽

Atsushi Nakajima ◽

Nobutaka Fujisawa ◽

Hirokazu Takahashi ◽

Ikuko Ikeda ◽

...

Keyword(s):

T Cell ◽

Epithelial Cell ◽

Colon Carcinogenesis ◽

Peroxisome Proliferator ◽

Cell Turnover ◽

Colonic Epithelial Cell ◽

Peroxisome Proliferator Activated Receptor ◽

T Cell Factor

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Ligand Activation of Peroxisome Proliferator–Activated Receptor β Inhibits Colon Carcinogenesis

Cancer Research ◽

10.1158/0008-5472.can-05-4277 ◽

2006 ◽

Vol 66 (8) ◽

pp. 4394-4401 ◽

Cited By ~ 101

Author(s):

Holly E. Marin ◽

Marjorie A. Peraza ◽

Andrew N. Billin ◽

Timothy M. Willson ◽

Jerrold M. Ward ◽

...

Keyword(s):

Colon Carcinogenesis ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Ligand Activation

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Ligand activation of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms

Carcinogenesis ◽

10.1093/carcin/bgm209 ◽

2007 ◽

Vol 29 (1) ◽

pp. 169-176 ◽

Cited By ~ 51

Author(s):

Holly E. Hollingshead ◽

Michael G. Borland ◽

Andrew N. Billin ◽

Timothy M. Willson ◽

Frank J. Gonzalez ◽

...

Keyword(s):

Colon Carcinogenesis ◽

Cyclooxygenase 2 ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Ligand Activation ◽

Signaling Mechanisms

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Impaired endogenous activation of peroxisome proliferator activated receptor (PPAR)α by human colon cancers

Gastroenterology ◽

10.1016/s0016-5085(01)82506-3 ◽

2001 ◽

Vol 120 (5) ◽

pp. A505-A505

Author(s):

L JACKSON ◽

A BENNETT ◽

C HAWKEY

Keyword(s):

Human Colon ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Colon Cancers

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Peroxisome proliferator-activated receptor (PPAR)-γ ligand inhibits the progression of pancreatic fibrosis in vivo and profibrogenic action in pancreatic myofibroblast

Gastroenterology ◽

10.1016/s0016-5085(01)80545-x ◽

2001 ◽

Vol 120 (5) ◽

pp. A111-A111

Author(s):

K SHIMIZU ◽

S HISADA ◽

K SHIRATORI ◽

M KOBAYASHI ◽

N HAYASHI

Keyword(s):

Pancreatic Fibrosis ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Ppar Γ

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Effect of troglitazone, an inducer of the peroxisome proliferator-activated receptor γ (PPARγ), on uterine leiomyoma development in the guinea pig model

Journal of the Society for Gynecologic Investigation ◽

10.1016/s1071-5576(97)86654-3 ◽

1998 ◽

Vol 5 (1) ◽

pp. 180A-180A

Author(s):

J TSIBRIS ◽

K PORTER ◽

A JAZAYERI ◽

S NICOSIA ◽

G PORTER ◽

...

Keyword(s):

Guinea Pig ◽

Uterine Leiomyoma ◽

Pig Model ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Guinea Pig Model

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