Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I

Edward T Chouchani; Carmen Methner; Sergiy M Nadtochiy; Angela Logan; Victoria R Pell; Shujing Ding; Andrew M James; Helena M Cochemé; Johannes Reinhold; Kathryn S Lilley; Linda Partridge; Ian M Fearnley; Alan J Robinson; Richard C Hartley; Robin A J Smith; Thomas Krieg; Paul S Brookes; Michael P Murphy

doi:10.1038/nm.3212

Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I

Nature Medicine ◽

10.1038/nm.3212 ◽

2013 ◽

Vol 19 (6) ◽

pp. 753-759 ◽

Cited By ~ 356

Author(s):

Edward T Chouchani ◽

Carmen Methner ◽

Sergiy M Nadtochiy ◽

Angela Logan ◽

Victoria R Pell ◽

...

Keyword(s):

Complex I ◽

Mitochondrial Complex I ◽

Mitochondrial Complex ◽

Cysteine Switch

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Faculty Opinions recommendation of Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718039871.793488061 ◽

2013 ◽

Author(s):

Fumito Ichinose

Keyword(s):

Complex I ◽

Mitochondrial Complex I ◽

Mitochondrial Complex ◽

Cysteine Switch

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Faculty Opinions recommendation of Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718039871.793480640 ◽

2013 ◽

Author(s):

Thomas W von Geldern

Keyword(s):

Complex I ◽

Mitochondrial Complex I ◽

Mitochondrial Complex ◽

Cysteine Switch

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6 S-Nitrosation of a Cysteine Switch on Mitochondrial Complex I Protects from Acute Ischaemia-Reperfusion Damage and Post Myocardial Infarction Heart Failure

Heart ◽

10.1136/heartjnl-2013-305297.6 ◽

2014 ◽

Vol 100 (Suppl 1) ◽

pp. A3.2-A3

Author(s):

E T Chouchani ◽

V R Pell ◽

C Methner ◽

G Buonincontri ◽

M P Murphy ◽

...

Keyword(s):

Myocardial Infarction ◽

Heart Failure ◽

Complex I ◽

Post Myocardial Infarction ◽

Mitochondrial Complex I ◽

Mitochondrial Complex ◽

Acute Ischaemia ◽

Ischaemia Reperfusion ◽

Infarction Heart ◽

Cysteine Switch

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Effects of lithium treatment on oxidative stress markers in mitochondrial complex I and complex III inhibition and after CO2 exposure in SH-SY5Y cells

10.31487/j.nnb.2019.01.001 ◽

2019 ◽

Author(s):

Frederic Marmol

Keyword(s):

Oxidative Stress ◽

Complex I ◽

Lithium Treatment ◽

Complex Iii ◽

Mitochondrial Complex I ◽

Oxidative Stress Markers ◽

Mitochondrial Complex ◽

Stress Markers

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Faculty Opinions recommendation of Sequence variation in mitochondrial complex I genes: mutation or polymorphism?

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047896.497919 ◽

2006 ◽

Author(s):

Anders Oldfors

Keyword(s):

Complex I ◽

Sequence Variation ◽

Mitochondrial Complex I ◽

Mitochondrial Complex

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Faculty Opinions recommendation of Functional modules and structural basis of conformational coupling in mitochondrial complex I.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3838956.4838055 ◽

2010 ◽

Author(s):

Thomas Meier

Keyword(s):

Complex I ◽

Structural Basis ◽

Mitochondrial Complex I ◽

Functional Modules ◽

Mitochondrial Complex ◽

Conformational Coupling

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Faculty Opinions recommendation of PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718319149.793497763 ◽

2014 ◽

Author(s):

Ted Dawson ◽

Sheila Pirooznia

Keyword(s):

Complex I ◽

Mitochondrial Complex I ◽

Loss Of Function ◽

Mitochondrial Complex ◽

Complex I Activity

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Faculty Opinions recommendation of Mitochondrial complex I deficiency enhances skeletal myogenesis but impairs insulin signaling through SIRT1 inactivation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718433724.793502240 ◽

2014 ◽

Author(s):

David Lee ◽

Hannah Heywood

Keyword(s):

Insulin Signaling ◽

Complex I ◽

Mitochondrial Complex I ◽

Skeletal Myogenesis ◽

Mitochondrial Complex ◽

Complex I Deficiency

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Faculty Opinions recommendation of Atomic structure of the entire mammalian mitochondrial complex I.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726712868.793524599 ◽

2016 ◽

Author(s):

Michael B Sherman

Keyword(s):

Atomic Structure ◽

Complex I ◽

Mitochondrial Complex I ◽

Mitochondrial Complex

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CD147 Interacts with NDUFS6 in Regulating Mitochondrial Complex I Activity and the Mitochondrial Apoptotic Pathway in Human Malignant Melanoma Cells

Current Molecular Medicine ◽

10.2174/1566524014666141202144601 ◽

2014 ◽

Vol 14 (10) ◽

pp. 1252-1264 ◽

Cited By ~ 18

Author(s):

Z. Luo ◽

W. Zeng ◽

W. Tang ◽

T. Long ◽

J. Zhang ◽

...

Keyword(s):

Malignant Melanoma ◽

Complex I ◽

Melanoma Cells ◽

Mitochondrial Complex I ◽

Mitochondrial Complex ◽

Apoptotic Pathway ◽

Human Malignant Melanoma ◽

Mitochondrial Apoptotic Pathway ◽

Complex I Activity

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