Cidea is an essential transcriptional coactivator regulating mammary gland secretion of milk lipids

2012 ◽  
Vol 18 (2) ◽  
pp. 235-243 ◽  
Author(s):  
Wenshan Wang ◽  
Na Lv ◽  
Shasha Zhang ◽  
Guanghou Shui ◽  
Hui Qian ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Gland Secretion ◽  
Transcriptional Coactivator ◽  
Milk Lipids

scholarly journals A New Diagnostic Indicator Using Concanavalin A Low-Affinity Lactoferrin Levels in Mammary Gland Secretion in Mastitic Drying Cows

2006 ◽  
Vol 68 (1) ◽  
pp. 59-63 ◽  
Author(s):  
Yumiko KOMINE ◽  
Ken-ichi KOMINE ◽  
Kenzou KAI ◽  
Toshinobu KUROISHI ◽  
Masashi ITAGAKI ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Concanavalin A ◽  
Gland Secretion ◽  
Diagnostic Indicator

Mammary Gland Secretion pH and Impending Parturition in Ponies and Mares with and without Firocoxib

2018 ◽  
Vol 66 ◽  
pp. 248 ◽  
Author(s):  
J.T. Hayna ◽  
S.R. Randell ◽  
C.A. Burden ◽  
M.A. Pozor ◽  
S.A. Benson ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Gland Secretion

Changes in the quantity and composition of mammary gland secretion in the dry period between lactations: I. The beginning of the dry period

1967 ◽  
Vol 34 (1) ◽  
pp. 1-12 ◽  
Author(s):  
J. V. Wheelock ◽  
A. Smith ◽  
F. H. Dodd ◽  
R. L. J. Lyster
Keyword(s):  
Mammary Gland ◽  
Sodium Chloride ◽  
Secretory Activity ◽  
Gland Secretion ◽  
Dry Period ◽  
Proteose Peptone ◽  
Β Lactoglobulin

SummaryThe changes in the yield and composition of the mammary gland secretion in the first 16 days of the dry period have been investigated in 6 cows. The quantity of secretion, lactose, potassium, casein, α-lactalbumin, β-lactoglobulin and fat present in the gland decreased rapidly. A decrease was also observed for sodium, chloride, residual albumin and proteose-peptone + globulin but was much less marked. Changes in composition were qualitatively similar to those normally occurring at the end of lactation but they were much more pronounced. Within 8 days after drying-off the concentrations in the secretion of sodium, chloride and potassium were similar to those of blood. There were differences between, animals in the rate at which the changes developed. As the secretory activity of the gland ceased, the constituents of the mammary gland secretion appeared to be resorbed.

scholarly journals Structural Characterization of the Fibroblast Growth Factor-binding Protein Purified from Bovine Prepartum Mammary Gland Secretion

2000 ◽  
Vol 275 (26) ◽  
pp. 19469-19474 ◽  
Author(s):  
Rene Lametsch ◽  
Jan T. Rasmussen ◽  
Laust B. Johnsen ◽  
Stig Purup ◽  
Kristen Sejrsen ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Structural Characterization ◽  
Binding Protein ◽  
Gland Secretion ◽  
Fibroblast Growth ◽  
Factor Binding

scholarly journals Calf demand provision by mammary gland secretion during the first decade of post-natal development

Heliyon ◽  
2019 ◽  
Vol 5 (10) ◽  
pp. e02676
Author(s):  
Sergii Shapovalov ◽  
Sergei Mikhaylov ◽  
Skryl Andrey ◽  
Yelizaveta Chereshneva ◽  
Dibahan Tsomartova ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Gland Secretion

scholarly journals Mammary gland secretion: hormonal coordination of endocytosis and exocytosis

animal ◽  
2009 ◽  
Vol 3 (12) ◽  
pp. 1733-1742 ◽  
Author(s):  
S. Truchet ◽  
M. Ollivier-Bousquet
Keyword(s):  
Mammary Gland ◽  
Gland Secretion

scholarly journals Small Molecule Lactoferrin with an Inflammatory Effect But No Apparent Antibacterial Activity in Mastitic Mammary Gland Secretion

2005 ◽  
Vol 67 (7) ◽  
pp. 667-677 ◽  
Author(s):  
Ken-ichi KOMINE ◽  
Yumiko KOMINE ◽  
Toshinobu KUROISHI ◽  
Jin KOBAYASHI ◽  
Yoshiaki OBARA ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Mammary Gland ◽  
Small Molecule ◽  
Gland Secretion ◽  
Inflammatory Effect

scholarly journals Activation of Adipocyte mTORC1 Increases Milk Lipids in a Mouse Model of Lactation

2021 ◽  
Author(s):  
Noura El-Habbal ◽  
Allison C. Meyer ◽  
Hannah Hafner ◽  
JeAnna R. Redd ◽  
Zach Carlson ◽  
...  
Keyword(s):  
Gene Expression ◽  
Fatty Acids ◽  
Mammary Gland ◽  
Milk Fat ◽  
Saturated Fatty Acids ◽  
Milk Composition ◽  
Nutrient Sensing ◽  
Lower Percentage ◽  
Milk Lipids

Human milk is the recommended nutrient source for newborns. The mammary gland comprises multiple cell types including epithelial cells and adipocytes. The contributions of mammary adipocytes to breast milk composition and the intersections between mammary nutrient sensing and milk lipids are not fully understood. A major nutrient sensor in most tissues is the mechanistic target of rapamycin 1 (mTORC1). To assess the role of excess nutrient sensing on mammary gland structure, function, milk composition, and offspring weights, we used an Adiponectin-Cre driven Tsc1 knockout model of adipocyte mTORC1 hyperactivation. Our results show that the knockout dams have higher milk fat contributing to higher milk caloric density and heavier offspring weight during lactation. Additionally, milk of knockout dams displayed a lower percentage of saturated fatty acids, higher percentage of monounsaturated fatty acids, and a lower milk ω6: ω3 ratio driven by increases in Docosahexaenoic acid (DHA). Mammary gland gene expression analyses identified changes in eicosanoid metabolism, adaptive immune function and contractile gene expression. Together, these results suggest a novel role of adipocyte mTORC1 in mammary gland function and morphology, milk composition, and offspring growth.

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