Gene link to diabetic nephropathy

Nature India ◽  
2012 ◽  
Keyword(s):  
Diabetic Nephropathy

Abstract # P-17: Association of NQO1 (Rs1800566) Polymorphism with NQO1 Levels and Risk of Diabetic Nephropathy in Indian Population

2016 ◽  
Vol 22 ◽  
pp. 21
Author(s):  
Mohini Sharma ◽  
S. Gupta ◽  
M. Mehndiratta ◽  
O.P. Kalra ◽  
R. Shukla ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Indian Population

Licorice extract ameliorates diabetic nephropathy in rats

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
AA Hamza ◽  
GA Ramadan ◽  
MA Khasawneh
Keyword(s):  
Diabetic Nephropathy ◽  
Licorice Extract

Plasma D Dimer: A Useful Marker of Fibrin Breakdown in Renal Failure

1989 ◽  
Vol 61 (03) ◽  
pp. 522-525 ◽  
Author(s):  
M P Gordge ◽  
R W Faint ◽  
P B Rylance ◽  
H Ireland ◽  
D A Lane ◽  
...  
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Acute Renal Failure ◽  
Monoclonal Antibodies ◽  
Diabetic Nephropathy ◽  
Renal Disease ◽  
Plasma Concentrations ◽  
Significant Negative Correlation ◽  
Healthy Controls ◽  
D Dimer

SummaryD dimer and other large fragments produced during the breakdown of crosslinked fibrin may be measured by enzyme immunoassay using monoclonal antibodies. In 91 patients with renal disease and varying degrees of renal dysfunction, plasma D dimer showed no correlation with renal function, whereas FgE antigen, a fibrinogen derivative which is known to be cleared in part by the kidney, showed a significant negative correlation with creatinine clearance. Plasma concentrations of D dimer were, however, increased in patients with chronic renal failure (244 ± 3l ng/ml) (mean ± SEM) and diabetic nephropathy (308 ± 74 ng/ml), when compared with healthy controls (96 ± 13 ng/ml), and grossly elevated in patients with acute renal failure (2,451 ± 1,007 ng/ml). The results indicate an increase in fibrin formation and lysis, and not simply reduced elimination of D dimer by the kidneys, and are further evidence of activated coagulation in renal disease. D dimer appears to be a useful marker of fibrin breakdown in renal failure.

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