scholarly journals Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells

2015 ◽  
Vol 16 (9) ◽  
pp. 933-941 ◽  
Author(s):  
Philip Brennecke ◽  
Alejandro Reyes ◽  
Sheena Pinto ◽  
Kristin Rattay ◽  
Michelle Nguyen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Single Cell ◽  
Transcriptome Analysis ◽  
Expression Patterns ◽  
Thymic Epithelial Cells ◽  
Gene Expression Patterns ◽  
Ectopic Gene Expression ◽  
Medullary Thymic Epithelial Cells ◽  
Cell Transcriptome ◽  
Single Cell Transcriptome

scholarly journals Single-Cell Transcriptome Analysis of Human Adipose-Derived Stromal Cells Identifies a Contractile Cell Subpopulation

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Elize Wolmarans ◽  
Juanita Mellet ◽  
Chrisna Durandt ◽  
Fourie Joubert ◽  
Michael S. Pepper
Keyword(s):  
Single Cell ◽  
Transcriptome Analysis ◽  
Stromal Cells ◽  
Exploratory Study ◽  
Expression Patterns ◽  
Cell Subpopulation ◽  
Adipose Derived Stromal Cells ◽  
Cell Transcriptome ◽  
Population Doublings ◽  
Single Cell Transcriptome

The potential for human adipose-derived stromal cells (hASCs) to be used as a therapeutic product is being assessed in multiple clinical trials. However, much is still to be learned about these cells before they can be used with confidence in the clinical setting. An inherent characteristic of hASCs that is not well understood is their heterogeneity. The aim of this exploratory study was to characterize the heterogeneity of freshly isolated hASCs after two population doublings (P2) using single-cell transcriptome analysis. A minimum of two subpopulations were identified at P2. A major subpopulation was identified as contractile cells which, based on gene expression patterns, are likely to be pericytes and/or vascular smooth muscle cells (vSMCs).

Single-cell transcriptome analysis reveals widespread monoallelic gene expression in individual rice mesophyll cells

2017 ◽  
Vol 62 (19) ◽  
pp. 1304-1314 ◽  
Author(s):  
Yingying Han ◽  
Xiao Chu ◽  
Haopeng Yu ◽  
Ying-Ke Ma ◽  
Xiu-Jie Wang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Single Cell ◽  
Transcriptome Analysis ◽  
Mesophyll Cells ◽  
Cell Transcriptome ◽  
Single Cell Transcriptome

scholarly journals Cryopreservation of microglia enables single-cell RNA sequencing with minimal effects on disease-related gene expression patterns

iScience ◽  
2021 ◽  
Vol 24 (4) ◽  
pp. 102357
Author(s):  
Brenda Morsey ◽  
Meng Niu ◽  
Shetty Ravi Dyavar ◽  
Courtney V. Fletcher ◽  
Benjamin G. Lamberty ◽  
...  
Keyword(s):  
Gene Expression ◽  
Single Cell ◽  
Rna Sequencing ◽  
Expression Patterns ◽  
Gene Expression Patterns ◽  
Related Gene ◽  
Single Cell Rna Sequencing ◽  
Disease Related Gene

scholarly journals Single cell transcriptome analysis upon MCF-7 breast cancer

2010 ◽  
Vol 11 (Suppl 1) ◽  
pp. P8 ◽  
Author(s):  
Yih-Shien Chiang ◽  
Lock Seng ◽  
You-Yu Lin ◽  
Shih-Hao Chen ◽  
Yu-Chang Su ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Single Cell ◽  
Transcriptome Analysis ◽  
Cell Transcriptome ◽  
Single Cell Transcriptome ◽  
Mcf 7
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