Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons

2006 ◽  
Vol 38 (5) ◽  
pp. 518-520 ◽  
Author(s):  
Yevgenya Kraytsberg ◽  
Elena Kudryavtseva ◽  
Ann C McKee ◽  
Changiz Geula ◽  
Neil W Kowall ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Substantia Nigra ◽  
Functional Impairment ◽  
Dna Deletions ◽  
Human Substantia Nigra

Increased Mitochondrial DNA Deletions in Substantia Nigra Dopamine Neurons of the Aged Rat

2015 ◽  
Vol 7 (3) ◽  
pp. 155-160 ◽  
Author(s):  
Gemma M. Parkinson ◽  
Christopher V. Dayas ◽  
Doug W. Smith
Keyword(s):  
Mitochondrial Dna ◽  
Substantia Nigra ◽  
Dopamine Neurons ◽  
Aged Rat ◽  
Dna Deletions

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

2006 ◽  
Vol 38 (5) ◽  
pp. 515-517 ◽  
Author(s):  
Andreas Bender ◽  
Kim J Krishnan ◽  
Christopher M Morris ◽  
Geoffrey A Taylor ◽  
Amy K Reeve ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Substantia Nigra ◽  
Parkinson Disease ◽  
Dna Deletions

Bayesian Emulation and Calibration of a Stochastic Computer Model of Mitochondrial DNA Deletions in Substantia Nigra Neurons

2009 ◽  
Vol 104 (485) ◽  
pp. 76-87 ◽  
Author(s):  
Daniel A. Henderson ◽  
Richard J. Boys ◽  
Kim J. Krishnan ◽  
Conor Lawless ◽  
Darren J. Wilkinson
Keyword(s):  
Mitochondrial Dna ◽  
Substantia Nigra ◽  
Computer Model ◽  
Dna Deletions

scholarly journals Nature of Mitochondrial DNA Deletions in Substantia Nigra Neurons

2008 ◽  
Vol 82 (1) ◽  
pp. 228-235 ◽  
Author(s):  
Amy K. Reeve ◽  
Kim J. Krishnan ◽  
Joanna L. Elson ◽  
Christopher M. Morris ◽  
Andreas Bender ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Substantia Nigra ◽  
Dna Deletions

scholarly journals Mitochondrial DNA deletions in mice in men: Substantia nigra is much less affected in the mouse

2010 ◽  
Vol 1797 (6-7) ◽  
pp. 1159-1162 ◽  
Author(s):  
Xinhong Guo ◽  
Elena Kudryavtseva ◽  
Natalya Bodyak ◽  
Alexander Nicholas ◽  
Igor Dombrovsky ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Substantia Nigra ◽  
Dna Deletions
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