Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I

1995 ◽  
Vol 10 (4) ◽  
pp. 453-460 ◽  
Author(s):  
Markus Grompe ◽  
Sven Lindstedt ◽  
Muhsen Al-Dhalimy ◽  
Nancy G. Kennaway ◽  
John Papaconstantinou ◽  
...  
Keyword(s):  
Murine Model ◽  
Hepatic Dysfunction ◽  
Type I ◽  
Tyrosinaemia Type ◽  
Pharmacological Correction

Therapeutic trials in the murine model of hereditary tyrosinaemia type I: A progress report

1998 ◽  
Vol 21 (5) ◽  
pp. 518-531 ◽  
Author(s):  
M. Grompe ◽  
K. Overturf ◽  
M. Al-Dhalimy ◽  
M. Finegold
Keyword(s):  
Murine Model ◽  
Progress Report ◽  
Type I ◽  
Tyrosinaemia Type ◽  
Therapeutic Trials

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I

1996 ◽  
Vol 12 (3) ◽  
pp. 266-273 ◽  
Author(s):  
Ken Overturf ◽  
Muhsen Al-Dhalimy ◽  
Robert Tanguay ◽  
Mark Brantly ◽  
Ching-Nan Ou ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Murine Model ◽  
Type I ◽  
Tyrosinaemia Type

A novel transgenic murine model with persistently brittle bones simulating osteogenesis imperfecta type I

Bone ◽  
2019 ◽  
Vol 127 ◽  
pp. 646-655 ◽  
Author(s):  
Yi Liu ◽  
Jianhai Wang ◽  
Shuo Liu ◽  
Mingjie Kuang ◽  
Yaqing Jing ◽  
...  
Keyword(s):  
Osteogenesis Imperfecta ◽  
Murine Model ◽  
Type I ◽  
Osteogenesis Imperfecta Type ◽  
Transgenic Murine Model ◽  
Brittle Bones ◽  
Osteogenesis Imperfecta Type I

Formalin-Fixed Staphylococcus aureus Particles Prevent Allergic Sensitization in a Murine Model of Type I Allergy

2007 ◽  
Vol 144 (3) ◽  
pp. 183-196 ◽  
Author(s):  
Karina Gisch ◽  
Nadine Gehrke ◽  
Matthias Bros ◽  
Christina Priesmeyer ◽  
Jürgen Knop ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Murine Model ◽  
Allergic Sensitization ◽  
Type I ◽  
Type I Allergy ◽  
Formalin Fixed

scholarly journals Sexual behaviour in a murine model of mucopolysaccharidosis type I (MPS I)

PLoS ONE ◽  
2019 ◽  
Vol 14 (12) ◽  
pp. e0220429 ◽  
Author(s):  
Ana Barbosa Mendes ◽  
Cinthia Castro do Nascimento ◽  
Vânia D’Almeida
Keyword(s):  
Sexual Behaviour ◽  
Murine Model ◽  
Type I ◽  
Mucopolysaccharidosis Type ◽  
Mucopolysaccharidosis Type I ◽  
Mps I

Liver transplantation in nine Spanish patients with tyrosinaemia type I

1995 ◽  
Vol 18 (2) ◽  
pp. 119-122 ◽  
Author(s):  
C. P�rez-Cerd� ◽  
B. Merinero ◽  
P. Sanz ◽  
M. Castro ◽  
J. Gangoiti ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Type I ◽  
Tyrosinaemia Type

scholarly journals ICSBP-mediated immune protection against BCR-ABL–induced leukemia requires the CCL6 and CCL9 chemokines

Blood ◽  
2009 ◽  
Vol 113 (16) ◽  
pp. 3813-3820 ◽  
Author(s):  
Valentina Nardi ◽  
Olaia Naveiras ◽  
Mohammad Azam ◽  
George Q. Daley
Keyword(s):  
Murine Model ◽  
Consensus Sequence ◽  
Myelogenous Leukemia ◽  
Transformed Cells ◽  
Type I ◽  
Immune Protection ◽  
Immune Mechanism ◽  
Type I Ifns ◽  
New Strategies

Abstract Interferon (IFN) is effective at inducing complete remissions in patients with chronic myelogenous leukemia (CML), and evidence supports an immune mechanism. Here we show that the type I IFNs (alpha and beta) regulate expression of the IFN consensus sequence-binding protein (ICSBP) in BCR-ABL–transformed cells and as shown previously for ICSBP, induce a vaccine-like immunoprotective effect in a murine model of BCR-ABL–induced leukemia. We identify the chemokines CCL6 and CCL9 as genes prominently induced by the type I IFNs and ICSBP, and demonstrate that these immunomodulators are required for the immunoprotective effect of ICSBP expression. Insights into the role of these chemokines in the antileukemic response of IFNs suggest new strategies for immunotherapy of CML.

Alterations of hepatic peroxisomes in tyrosinaemia type I: Return to fetal type?

1998 ◽  
Vol 21 (3) ◽  
pp. 186-190 ◽  
Author(s):  
I. Kerckaert ◽  
T. J. De Koning ◽  
B. T. Poll-The ◽  
F. Roels
Keyword(s):  
Type I ◽  
Tyrosinaemia Type
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