Does antimicrobial prophylaxis affect recurrent urinary tract infections and bacterial resistance in children?

2008 ◽  
Vol 5 (4) ◽  
pp. 186-187
Author(s):  
Simon Waller ◽  
T Jim Beattie
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Bacterial Resistance ◽  
Antimicrobial Prophylaxis ◽  
Recurrent Urinary Tract Infections ◽  
Tract Infections

scholarly journals Changes in bacterial resistance patterns in children with urinary tract infections on antimicrobial prophylaxis at University Hospital in Split

2011 ◽  
Vol 17 (7) ◽  
pp. CR355-CR361 ◽  
Author(s):  
Tanja Ilić ◽  
Sanda Gračan ◽  
Adela Arapović ◽  
Vesna Čapkun ◽  
Mirna Šubat-Dežulović ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Bacterial Resistance ◽  
Antimicrobial Prophylaxis ◽  
University Hospital ◽  
Resistance Patterns ◽  
Tract Infections

scholarly journals Prevention of Recurrent Urinary Tract Infections in Postmenopausal Women

2014 ◽  
pp. 55-60
Author(s):  
Darrell Fernando ◽  
Budi I Santoso
Keyword(s):  
Systematic Review ◽  
Urinary Tract ◽  
Postmenopausal Women ◽  
Urinary Tract Infections ◽  
Antimicrobial Prophylaxis ◽  
Prophylaxis Group ◽  
Research Article ◽  
Recurrent Urinary Tract Infections ◽  
Significant Difference ◽  
Tract Infections

Objective: To determine the most effective and applicable methods to reduce recurrence of urinary tract infections in postmenopausal women. Method: A search was conducted on Pubmed, NEJM, BMJ, and Google. After screening and selection, six articles were considered useful; comprising of two original research articles, one systematic review, and three society guidelines. Result: Society guidelines recommended continuous antimicrobial prophylaxis, with postcoital antimicrobial prophylaxis as an alternative. The first research article found similar results in continous antimicrobial prophylaxis group and intermittent antimicrobial prophylaxis group. The second research article found no significant difference in cranberry and trimethoprim group. The systematic review revealed vaginal estrogens are effective in preventing recurrent UTI, but the type of estrogen is less clear. Oral estrogens are not effective. Conclusion: Prevention of recurrent urinary tract infections in postmenopausal women include risk factor identification, non-antimicrobial prophylaxis with cranberry and vaginal estrogen preparations, and antimicrobial prophylaxis (continuous or intermittent). Keywords: postmenopausal, prevention, recurrent urinary tract infection.

Weekly Sequential Antibioprophylaxis for Recurrent Urinary Tract Infections Among Patients With Neurogenic Bladder: A Randomized Controlled Trial

2019 ◽  
Author(s):  
Aurélien Dinh ◽  
Marie-Charlotte Hallouin-Bernard ◽  
Benjamin Davido ◽  
Adrien Lemaignen ◽  
Frédérique Bouchand ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Neurogenic Bladder ◽  
Urinary Tract Infections ◽  
Bacterial Resistance ◽  
Controlled Trial ◽  
Group Versus ◽  
Control Group ◽  
Recurrent Urinary Tract Infections ◽  
Cord Injury ◽  
Tract Infections

Abstract Background Recurrent urinary tract infections (R-UTIs) are the main cause of morbidity and hospitalizations in subjects with neurogenic bladder (NB) due to spinal cord injury (SCI). We evaluated the efficacy of weekly oral cyclic antibiotic (WOCA) prophylaxis (ie, the alternate weekly administration of 2 antibiotics) in preventing R-UTIs. Methods Randomized (1:1), open-label, superiority-controlled trial compared WOCA prophylaxis to no prophylaxis (control) for 6 months in patients with NB due to SCI, using clean intermittent self-catheterization, and suffering from R-UTIs. Primary outcome was incidence of symptomatic antibiotic-treated UTIs. Secondary outcomes were number of febrile UTIs, number of hospitalizations, WOCA tolerance, antibiotic consumption, number of negative urine cultures, and emergence of bacterial resistance in urinary, intestinal, and nasal microbiota. Results Forty-five patients were either allocated to the WOCA group (n = 23) or the control group (n = 22). Median (IQR) incidence of symptomatic antibiotic-treated UTIs was 1.0 (0.5–2.5) in the WOCA group versus 2.5 (1.2–4.0) (P = .0241) in the control group. No febrile UTIs were recorded in the WOCA group versus 9 (45.0%) (P < .001) in the control group. The median number of additional antibiotic treatment was 0.0 (IQR, 0.0–2.0) versus 3.0 (2.0–5.0) (P = .004) in the WOCA and control groups, respectively. Only few adverse events were reported. No impact on emergence of bacterial resistance was observed. Conclusions WOCA is efficient and well tolerated in preventing R-UTIs in SCI patients. In our study, we did not observe any emergence of antibiotic resistance in digestive and nasal microbiological cultures. Clinical Trials Registration NCT01388413.

The influence of smoking on bacterial resistance after vaccine or antibiotic prophylaxis against recurrent urinary tract infections

2020 ◽  
Vol 44 (7) ◽  
pp. 497-504
Author(s):  
M.F. Lorenzo-Gómez ◽  
M.T. Santos-Antunes ◽  
A. Nieto-Huertos ◽  
A. Lorenzo-Gómez ◽  
M.T. Marquez-Sanchez ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Antibiotic Prophylaxis ◽  
Urinary Tract Infections ◽  
Bacterial Resistance ◽  
Recurrent Urinary Tract Infections ◽  
Tract Infections
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