High lymph-node yield improves the prognostic value of esophageal cancer staging

2008 ◽  
Vol 5 (7) ◽  
pp. 366-367
Keyword(s):  
Esophageal Cancer ◽  
Lymph Node ◽  
Prognostic Value ◽  
Cancer Staging ◽  
Lymph Node Yield ◽  
High Lymph Node ◽  
Node Yield

Prognostic Value of Lymph Node Yield on Overall Survival in Esophageal Cancer Patients

2019 ◽  
Vol 269 (2) ◽  
pp. 261-268 ◽  
Author(s):  
Els Visser ◽  
Sheraz R. Markar ◽  
Jelle P. Ruurda ◽  
George B. Hanna ◽  
Richard van Hillegersberg
Keyword(s):  
Overall Survival ◽  
Esophageal Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Prognostic Value ◽  
Lymph Node Yield ◽  
Node Yield

scholarly journals A High Lymph Node Yield is Associated with Prolonged Survival in Elderly Patients Undergoing Curative Gastrectomy for Cancer: A Dutch Population-Based Cohort Study

2017 ◽  
Vol 24 (8) ◽  
pp. 2213-2223 ◽  
Author(s):  
Hylke J. F. Brenkman ◽  
Lucas Goense ◽  
Lodewijk A. Brosens ◽  
Nadia Haj Mohammad ◽  
Frank P. Vleggaar ◽  
...  
Keyword(s):  
Cohort Study ◽  
Lymph Node ◽  
Elderly Patients ◽  
Population Based ◽  
Prolonged Survival ◽  
Dutch Population ◽  
Curative Gastrectomy ◽  
Lymph Node Yield ◽  
High Lymph Node ◽  
Node Yield

Prognostic Value of Lymph Node Yield After Neoadjuvant Chemoradiation for Gastric Cancer

2019 ◽  
Vol 27 (2) ◽  
pp. 534-542 ◽  
Author(s):  
Casey J. Allen ◽  
Timothy J. Vreeland ◽  
Timothy E. Newhook ◽  
Prajnan Das ◽  
Bruce D. Minsky ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Prognostic Value ◽  
Neoadjuvant Chemoradiation ◽  
Lymph Node Yield ◽  
Node Yield

scholarly journals High Lymph Node Yield is Related to Microsatellite Instability in Colon Cancer

2011 ◽  
Vol 19 (4) ◽  
pp. 1222-1230 ◽  
Author(s):  
E. J. Th. Belt ◽  
E. A. te Velde ◽  
O. Krijgsman ◽  
R. P. M. Brosens ◽  
M. Tijssen ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Node ◽  
Microsatellite Instability ◽  
Lymph Node Yield ◽  
High Lymph Node ◽  
Node Yield

scholarly journals Resection of the irradiated esophagus: the impact of lymph node yield on survival

2020 ◽  
Vol 33 (10) ◽  
Author(s):  
V R Esposito ◽  
B A Yerokun ◽  
M S Mulvihill ◽  
M L Cox ◽  
B Y Andrew ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Lymph Node ◽  
Cox Regression ◽  
Cox Proportional Hazards Model ◽  
Rank Test ◽  
Preoperative Radiation ◽  
Lymph Node Yield ◽  
Extensive Lymph Node ◽  
The Impact ◽  
Node Yield

SUMMARY There is debate surrounding the appropriate threshold for lymph node harvest during esophagectomy in patients with esophageal cancer, specifically for those receiving preoperative radiation. The purpose of this study was to determine the impact of lymph node yield on survival in patients receiving preoperative chemoradiation for esophageal cancer. The National Cancer Database (NCDB) was utilized to identify patients with esophageal cancer that received preoperative radiation. The cohort was divided into patients undergoing minimal (<9) or extensive (≥9) lymph node yield. Demographic, operative, and postoperative outcomes were compared between the groups. Kaplan–Meier analysis with the log rank test was used to compare survival between the yield groups. Cox proportional hazards model was used to determine the association between lymph node yield and survival. In total, 886 cases were included: 349 (39%) belonging to the minimal node group and 537 (61%) to the extensive group. Unadjusted 5-year survival was similar between the minimal and extensive groups, respectively (37.3% vs. 38.8%; P > 0.05). After adjustment using Cox regression, extensive lymph node yield was associated with survival (hazard ratio 0.80, confidence interval 0.66–0.98, P = 0.03). This study suggests that extensive lymph node yield is advantageous for patients with esophageal cancer undergoing esophagectomy following induction therapy. This most likely reflects improved diagnosis and staging with extensive yield.

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