scholarly journals Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
G. Stefano Brigidi ◽  
Brendan Santyr ◽  
Jordan Shimell ◽  
Blair Jovellar ◽  
Shernaz X. Bamji
Keyword(s):  
Acyl Transferase ◽  
Regulated Trafficking

Identification of the Flavobacterium johnsoniae cysteate‐fatty acyl transferase required for capnine synthesis and for efficient gliding motility

2021 ◽  
Author(s):  
Miguel Ángel Vences‐Guzmán ◽  
Rafael Peña‐Miller ◽  
Nancy Adriana Hidalgo‐Aguilar ◽  
Maritza Lorena Vences‐Guzmán ◽  
Ziqiang Guan ◽  
...  
Keyword(s):  
Fatty Acyl ◽  
Gliding Motility ◽  
Acyl Transferase ◽  
Flavobacterium Johnsoniae

A novel route for aspartame production by combining enzymatic and chemical reactions for industrial use

2020 ◽  
Vol 85 (2) ◽  
pp. 464-466
Author(s):  
Kenzo Yokozeki ◽  
Isao Abe
Keyword(s):  
Aqueous Solution ◽  
Amino Acid ◽  
Chemical Reactions ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
Acyl Transferase ◽  
Enzymatic Production ◽  
Production Route ◽  
Industrial Use ◽  
Hcl Removal

ABSTRACT Here, we report a novel industrial aspartame production route, involving the enzymatic production of α-l-aspartyl-l-phenylalanine β-methylester from l-aspartic acid dimethylester and l-phenylalanine by α-amino acid ester acyl transferase. The route also involves the chemical transformation of α-l-aspartyl-l-phenylalanine β-methylester to α-l-aspartyl-l-phenylalanine methylester hydrochloride (aspartame hydrochloride) in an aqueous solution with methanol and HCl, followed by HCl removal to form aspartame.

scholarly journals SNARE phosphorylation: a control mechanism for insulin-stimulated glucose transport and other regulated exocytic events

2017 ◽  
Vol 45 (6) ◽  
pp. 1271-1277 ◽  
Author(s):  
Kamilla M.E. Laidlaw ◽  
Rachel Livingstone ◽  
Mohammed Al-Tobi ◽  
Nia J. Bryant ◽  
Gwyn W. Gould
Keyword(s):  
Membrane Fusion ◽  
Molecular Mechanisms ◽  
Membrane Receptors ◽  
Multivesicular Bodies ◽  
Attachment Protein ◽  
Protein Receptor ◽  
Sensitive Factor ◽  
Plasma Membrane Receptors ◽  
Regulated Trafficking ◽  
Receptor Family

Trafficking within eukaryotic cells is a complex and highly regulated process; events such as recycling of plasma membrane receptors, formation of multivesicular bodies, regulated release of hormones and delivery of proteins to membranes all require directionality and specificity. The underpinning processes, including cargo selection, membrane fusion, trafficking flow and timing, are controlled by a variety of molecular mechanisms and engage multiple families of lipids and proteins. Here, we will focus on control of trafficking processes via the action of the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) family of proteins, in particular their regulation by phosphorylation. We will describe how these proteins are controlled in a range of regulated trafficking events, with particular emphasis on the insulin-stimulated delivery of glucose transporters to the surface of adipose and muscle cells. Here, we focus on a few examples of SNARE phosphorylation which exemplify distinct ways in which SNARE machinery phosphorylation may regulate membrane fusion.

scholarly journals DKWSLLL, a Versatile DXXXLL-Type Signal with Distinct Roles in the Cu+-Regulated Trafficking of ATP7B

Traffic ◽  
2014 ◽  
Vol 15 (8) ◽  
pp. 839-860 ◽  
Author(s):  
Vasiliki Lalioti ◽  
Sonia Hernandez-Tiedra ◽  
Ignacio V. Sandoval
Keyword(s):  
Regulated Trafficking
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