scholarly journals Cellulosome stoichiometry in Clostridium cellulolyticum is regulated by selective RNA processing and stabilization

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Chenggang Xu ◽  
Ranran Huang ◽  
Lin Teng ◽  
Xiaoyan Jing ◽  
Jianqiang Hu ◽  
...  
Bionatura ◽  
2020 ◽  
Vol 5 (4) ◽  
pp. 1423-1426
Author(s):  
Bruna Rech ◽  
Fernando A. Gonzales-Zubiate

Ribonucleases (RNases) functions in the cell include precise maturation of non- coding RNAs and degradation of specific RNA transcripts that are no longer necessary. RNAses are present in the cell as single units or assembled as multimeric complexes; one of these complexes is the RNA exosome, a highly conserved complex essential for RNA processing and degradation. In the yeast Saccharomyces cerevisiae, the RNA exosome comprises eleven subunits, two with catalytic activity: Rrp6 and Rrp44, where the Rrp6 subunit is exclusively nuclear. Despite the RNA exosome has been intensively investigated since its discovery in 1997, only a few studies were accomplished concerning its nuclear transport. This review describes recent research about cellular localization and transport of this essential complex.


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