Reelin delays amyloid-beta fibril formation and rescues cognitive deficits in a model of Alzheimer’s disease

Lluís Pujadas; Daniela Rossi; Rosa Andrés; Cátia M. Teixeira; Bernat Serra-Vidal; Antoni Parcerisas; Rafael Maldonado; Ernest Giralt; Natàlia Carulla; Eduardo Soriano

doi:10.1038/ncomms4443

Reelin delays amyloid-beta fibril formation and rescues cognitive deficits in a model of Alzheimer’s disease

Nature Communications ◽

10.1038/ncomms4443 ◽

2014 ◽

Vol 5 (1) ◽

Cited By ~ 76

Author(s):

Lluís Pujadas ◽

Daniela Rossi ◽

Rosa Andrés ◽

Cátia M. Teixeira ◽

Bernat Serra-Vidal ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Beta ◽

Cognitive Deficits ◽

Fibril Formation ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717977209.793470743 ◽

2013 ◽

Author(s):

Matt Kaeberlein

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Beta ◽

Cognitive Deficits ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1008787.111209 ◽

2002 ◽

Author(s):

John Toedt

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Beta ◽

Fibril Formation ◽

New Class

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Faculty Opinions recommendation of Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1099453.555719 ◽

2008 ◽

Author(s):

Massimo Pandolfo

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Amyloid Beta ◽

Model Of Alzheimer’S Disease ◽

Local Toxicity ◽

Rapid Appearance

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Faculty Opinions recommendation of Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718520520.793504888 ◽

2015 ◽

Author(s):

Amy Barrios

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficits ◽

Tyrosine Phosphatase ◽

Model Of Alzheimer’S Disease

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Faculty Opinions recommendation of A novel GLP-1/GIP/Gcg triagonist reduces cognitive deficits and pathology in the 3xTg mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732740978.793572425 ◽

2020 ◽

Author(s):

Venkateswarlu Kanamarlapudi

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficits ◽

Model Of Alzheimer’S Disease

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Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer’s disease

Molecular Psychiatry ◽

10.1038/mp.2016.112 ◽

2016 ◽

Vol 22 (4) ◽

pp. 605-614 ◽

Cited By ~ 13

Author(s):

R Derungs ◽

G G Camici ◽

R D Spescha ◽

T Welt ◽

C Tackenberg ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Cognitive Deficits ◽

Mitochondrial Function ◽

Adaptor Protein ◽

Transgenic Mouse Model ◽

Genetic Ablation ◽

Model Of Alzheimer’S Disease

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P1-033: Cognitive deficits and plaque deposition in a gene-targeted mouse model of Alzheimer's disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2009.04.036 ◽

2009 ◽

Vol 5 (4S_Part_6) ◽

pp. P181-P181

Author(s):

John Ciallella ◽

Heather Hain ◽

Bryan Strenkowski ◽

Michelle Hogga ◽

Stacey Galvin ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Deficits ◽

Plaque Deposition ◽

Model Of Alzheimer’S Disease

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Ghrelin mimetic MK-677 alleviates amyloid beta-related pathology in 5XFAD mice, an animal model of Alzheimer’s disease

European Neuropsychopharmacology ◽

10.1016/s0924-977x(17)31791-1 ◽

2017 ◽

Vol 27 ◽

pp. S1022-S1023

Author(s):

S.M. Lee ◽

M.H. Hong ◽

H.Y. Chung ◽

M. Moon

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Animal Model ◽

Amyloid Beta ◽

Model Of Alzheimer’S Disease ◽

5Xfad Mice

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Faculty Opinions recommendation of Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer's disease-type pathology and cognitive deficits in APP/PS1 mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.738329210.793584304 ◽

2021 ◽

Author(s):

Nikolay Dokholyan ◽

Dongyan Zhang

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Beta ◽

Cognitive Deficits ◽

Disease Type

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Tannoid principles ofEmblica officinalisrenovate cognitive deficits and attenuate amyloid pathologies against aluminum chloride induced rat model of Alzheimer's disease

Nutritional Neuroscience ◽

10.1179/1476830515y.0000000016 ◽

2015 ◽

Vol 19 (6) ◽

pp. 269-278 ◽

Cited By ~ 33

Author(s):

Arokiasamy Justin Thenmozhi ◽

Mathiyazahan Dhivyabharathi ◽

Tharsius Raja William Raja ◽

Thamilarasan Manivasagam ◽

Musthafa Mohamed Essa

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Deficits ◽

Rat Model ◽

Aluminum Chloride ◽

Model Of Alzheimer’S Disease

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