scholarly journals Dynamic reassortments and genetic heterogeneity of the human-infecting influenza A (H7N9) virus

2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Lunbiao Cui ◽  
Di Liu ◽  
Weifeng Shi ◽  
Jingcao Pan ◽  
Xian Qi ◽  
...  
Keyword(s):  
Genetic Heterogeneity ◽  
Influenza A ◽  
H7n9 Virus

Rapid hemagglutinin subtyping of novel avian-origin influenza A(H7N9) virus using a diagnostic microarray

2014 ◽  
Vol 8 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Dong-Hun Lee ◽  
Ji-Hoon Kim ◽  
Seong-Su Yuk ◽  
Jung-Hoon Kwon ◽  
Hyunseok Cho ◽  
...  
Keyword(s):  
Influenza A ◽  
H7n9 Virus ◽  
Avian Origin

scholarly journals Asymptomatic, Mild, and Severe Influenza A(H7N9) Virus Infection in Humans, Guangzhou, China

2014 ◽  
Vol 20 (9) ◽  
Author(s):  
Zongqiu Chen ◽  
Hui Liu ◽  
Jianyun Lu ◽  
Lei Luo ◽  
Kuibiao Li ◽  
...  
Keyword(s):  
Virus Infection ◽  
Influenza A ◽  
H7n9 Virus ◽  
Severe Influenza

scholarly journals Biological characterisation of the emerged highly pathogenic avian influenza (HPAI) A(H7N9) viruses in humans, in mainland China, 2016 to 2017

2017 ◽  
Vol 22 (19) ◽  
Author(s):  
Wenfei Zhu ◽  
Jianfang Zhou ◽  
Zi Li ◽  
Lei Yang ◽  
Xiyan Li ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Mainland China ◽  
H7n9 Virus ◽  
Highly Pathogenic ◽  
Pathogenic Avian Influenza ◽  
Binding Preference ◽  
Severe Infections ◽  
Epidemic Wave

With no or low virulence in poultry, avian influenza A(H7N9) virus has caused severe infections in humans. In the current fifth epidemic wave, a highly pathogenic avian influenza (HPAI) H7N9 virus emerged. The insertion of four amino acids (KRTA) at the haemagglutinin (HA) cleavage site enabled trypsin-independent infectivity of this virus. Although maintaining dual receptor-binding preference, its HA antigenicity was distinct from low-pathogenic avian influenza A(H7N9). The neuraminidase substitution R292K conferred a multidrug resistance phenotype.

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