scholarly journals Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells

2012 ◽  
Vol 3 (1) ◽  
Author(s):  
Houbo Jiang ◽  
Yong Ren ◽  
Eunice Y. Yuen ◽  
Ping Zhong ◽  
Mahboobe Ghaedi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Dopaminergic Neurons ◽  
Midbrain Dopaminergic Neurons ◽  
Induced Pluripotent

Midbrain Dopaminergic Neurons Differentiated from Human-Induced Pluripotent Stem Cells

2019 ◽  
pp. 97-118 ◽  
Author(s):  
Fabiano Araújo Tofoli ◽  
Ana Teresa Silva Semeano ◽  
Ágatha Oliveira-Giacomelli ◽  
Maria Carolina Bittencourt Gonçalves ◽  
Merari F. R. Ferrari ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Dopaminergic Neurons ◽  
Midbrain Dopaminergic Neurons ◽  
Induced Pluripotent

scholarly journals Efficient Generation of Functional Dopaminergic Neurons from Human Induced Pluripotent Stem Cells Under Defined Conditions

Stem Cells ◽  
2010 ◽  
Vol 28 (10) ◽  
pp. 1893-1904 ◽  
Author(s):  
Andrzej Swistowski ◽  
Jun Peng ◽  
Qiuyue Liu ◽  
Prashant Mali ◽  
Mahendra S. Rao ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Dopaminergic Neurons ◽  
Efficient Generation ◽  
Induced Pluripotent

scholarly journals Dopaminergic Neurons Derived from Human Induced Pluripotent Stem Cells Survive and Integrate into 6-OHDA-Lesioned Rats

2010 ◽  
Vol 19 (7) ◽  
pp. 1017-1023 ◽  
Author(s):  
Jingli Cai ◽  
Ming Yang ◽  
Elizabeth Poremsky ◽  
Sarah Kidd ◽  
Jay S. Schneider ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Dopaminergic Neurons ◽  
Induced Pluripotent

scholarly journals Transmission Mechanism of Lewy Body-Like α-Synucleinopathies in Dopaminergic Neurons Derived from Human Induced Pluripotent Stem Cells

2018 ◽  
Vol 4 ◽  
pp. e25423
Author(s):  
Cheng Lin
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Dopaminergic Neurons ◽  
Lewy Body ◽  
Lewy Bodies ◽  
Transmission Mechanism ◽  
Induced Pluripotent

Grafting of cells in Parkinson's disease (PD) results in a prion-like infection, exhibiting a Lewy body-like pathology, caused by the recipient cells. The transmission mechanism of Lewy bodies is not completely understood. Therefore, a research idea with a novel experimental strategy is proposed to investigate the transmission mechanism of α-synuclein pathology using PD patient-derived human induced pluripotent stem cells (hiPSC) in an in vitro human cellular and molecular PD model and in vivo mouse PD model for dopaminergic neuron transplantation.

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