scholarly journals A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Tetsuro Yoshimaru ◽  
Masaya Ono ◽  
Yoshimi Bando ◽  
Yi-An Chen ◽  
Kenji Mizuguchi ◽  
...  
2011 ◽  
Vol 11 (7) ◽  
pp. 523-532 ◽  
Author(s):  
John J. Tyson ◽  
William T. Baumann ◽  
Chun Chen ◽  
Anael Verdugo ◽  
Iman Tavassoly ◽  
...  

2013 ◽  
Vol 220 (3) ◽  
pp. R25-R35 ◽  
Author(s):  
O Sukocheva ◽  
C Wadham

The signaling pathways activated by the steroid hormone oestrogen include a variety of cytoplasmic second messengers linked to a multitude of tissue-specific effects. In the last decade, sphingolipids and their membrane receptors were added to the list of oestrogen-activated mediators. Oestrogen triggers the sphingolipid signalling cascade in various tissues including breast cancer. Extensive research has shown that sphingolipids are the key regulatory molecules in growth factor networks. Sphingolipids can control the rate of cell proliferation and the differentiation outcome during malignant transformation. In this study, we summarise novel experimental evidences linking sphingolipids to oestrogen-activated effects, highlight the role of sphingolipids in cancer cells and discuss new avenues for future research at the intersection between oestrogen and sphingolipid signalling.


2010 ◽  
Vol 34 (8) ◽  
pp. S49-S49
Author(s):  
Lei Wang ◽  
Xun Zhou ◽  
Lihong Zhou ◽  
Yong Chen ◽  
Xun Zhu ◽  
...  

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
WY Liao ◽  
CN Shen ◽  
LH Lin ◽  
YL Yang ◽  
HY Han ◽  
...  

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