scholarly journals Bottom-up synthesis of chiral covalent organic frameworks and their bound capillaries for chiral separation

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Hai-Long Qian ◽  
Cheng-Xiong Yang ◽  
Xiu-Ping Yan
Keyword(s):  
Gas Chromatography ◽  
Chiral Separation ◽  
Capillary Columns ◽  
Organic Ligands ◽  
Covalent Organic Frameworks ◽  
Bottom Up ◽  
Repeatability And Reproducibility ◽  
Growth Approach ◽  
Chiral Gas Chromatography

Abstract Covalent organic frameworks (COFs) are a novel class of porous materials, and offer great potential for various applications. However, the applications of COFs in chiral separation and chiral catalysis are largely underexplored due to the very limited chiral COFs available and their challenging synthesis. Here we show a bottom-up strategy to construct chiral COFs and an in situ growth approach to fabricate chiral COF-bound capillary columns for chiral gas chromatography. We incorporate the chiral centres into one of the organic ligands for the synthesis of the chiral COFs. We subsequently in situ prepare the COF-bound capillary columns. The prepared chiral COFs and their bound capillary columns give high resolution for the separation of enantiomers with excellent repeatability and reproducibility. The proposed strategy provides a promising platform for the synthesis of chiral COFs and their chiral separation application.

scholarly journals In Situ Bottom-up Synthesis of Porphyrin-Based Covalent Organic Frameworks

2019 ◽  
Vol 141 (50) ◽  
pp. 19560-19564 ◽  
Author(s):  
Elham Tavakoli ◽  
Arvin Kakekhani ◽  
Shayan Kaviani ◽  
Peng Tan ◽  
Mahdi Mohammadi Ghaleni ◽  
...  
Keyword(s):  
Covalent Organic Frameworks ◽  
Bottom Up

An in situ growth approach to the fabrication of zeolite imidazolate framework-90 bonded capillary column for gas chromatography separation

The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 3107-3112 ◽  
Author(s):  
Ye-Yu Wu ◽  
Cheng-Xiong Yang ◽  
Xiu-Ping Yan
Keyword(s):  
Gas Chromatography ◽  
Stationary Phase ◽  
Capillary Column ◽  
Polar Compounds ◽  
In Situ Growth ◽  
Growth Approach ◽  
Polar Stationary Phase

Zeolite imidazolate framework-90 (ZIF-90) bonded capillary column was fabricated via an in situ growth approach. The prepared ZIF-90 bonded capillary column acts as a weak polar stationary phase and gave baseline separation of apolar and polar compounds.

Chiral separation of β-blockers after derivatization with (-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride by gas chromatography

2001 ◽  
Vol 24 (5) ◽  
pp. 402-406 ◽  
Author(s):  
Kyeong Ho Kim ◽  
Joo Hyun Lee ◽  
Mi Young Ko ◽  
Seon-Pyo Hong ◽  
Jeong Rok Youm
Keyword(s):  
Gas Chromatography ◽  
Chiral Separation ◽  
Β Blockers

scholarly journals Cell-free protein synthesis and in situ immobilization of deGFP-MatB in polymer microgels for malonate-to-malonyl CoA conversion

RSC Advances ◽  
2020 ◽  
Vol 10 (66) ◽  
pp. 40588-40596
Author(s):  
Tony Köhler ◽  
Thomas Heida ◽  
Sandra Hoefgen ◽  
Niclas Weigel ◽  
Vito Valiante ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Genetic Information ◽  
In Situ Immobilization ◽  
Bottom Up ◽  
Free Protein ◽  
Malonyl Coa ◽  
Cell Free Protein Synthesis

We describe a bottom-up approach towards functional enzymes utilizing microgels as carriers for genetic information that enable cell-free protein synthesis, in situ immobilization, and utilization of functional deGFP-MatB.

scholarly journals Diffusion-induced in situ growth of covalent organic frameworks for composite membranes

2019 ◽  
Vol 7 (45) ◽  
pp. 25802-25807 ◽  
Author(s):  
Priyanka Manchanda ◽  
Stefan Chisca ◽  
Lakshmeesha Upadhyaya ◽  
Valentina-Elena Musteata ◽  
Mark Carrington ◽  
...  
Keyword(s):  
Reaction Times ◽  
Composite Membranes ◽  
Thin Layers ◽  
In Situ Growth ◽  
Covalent Organic Frameworks ◽  
Polymeric Support ◽  
Ambient Conditions ◽  
Induction Method ◽  
Covalent Organic Framework

Thin layers of a covalent organic framework (COF) have been synthesized on a flexible polymeric support using a new diffusion-induction method under ambient conditions in reaction times as short as 3 hours.

Repeatability, Reproducibility, and Calibration of the MyotonPro® on Tissue Mimicking Phantoms

2013 ◽  
Author(s):  
John Dougherty ◽  
Emily Schaefer ◽  
Kalyani Nair ◽  
Joseph Kelly ◽  
Alfonse Masi
Keyword(s):  
Data Collection ◽  
Dynamic Stiffness ◽  
Correlation Study ◽  
Living Tissue ◽  
Polymeric Gel ◽  
Stiffness Properties ◽  
Tissue Phantoms ◽  
Repeatability And Reproducibility ◽  
Living Tissues

The MyotonPro® (Myoton AS, Tallinn, Estonia) is commonly used to quantify stiffness properties of living tissues in situ. Current studies quantify the dynamic stiffness properties of living tissues, but do not validate or compare these measurements to a standardized method. Additionally, living tissue, being dynamic in nature, presents much variability in data collection. To address these issues this study focuses on the repeatability and reproducibility of the MyotonPro® on polymeric gel-based tissue phantoms. In addition, a correlation study is also performed to translate dynamic stiffness to a more standardized property, Young’s modulus. Such studies help to confirm the reliability of the measurements obtained in situ.

Residue Analysis of Organophosphorus and Organochlorine Pesticides in Fatty Matrices by Gas Chromatography Coupled with Electron-Capture Detection

2006 ◽  
Vol 61 (5-6) ◽  
pp. 341-346 ◽  
Author(s):  
Jae-Woo Park ◽  
A. M. Abd El-Aty ◽  
Myoung-Heon Lee ◽  
Sung-Ok Song ◽  
Jae-Han Shim
Keyword(s):  
Gas Chromatography ◽  
Electron Capture ◽  
Simple Procedure ◽  
Linear Regression Analysis ◽  
Residue Analysis ◽  
Electron Capture Detection ◽  
Relative Standard ◽  
Wide Range ◽  
Repeatability And Reproducibility

A multiresidue method for the simultaneous determination of 22 organochlorine (OCs) and organophosphorus (Ops) pesticides (including isomers and metabolites), representing a wide range of physicochemical properties, was developed in fatty matrices extracted from meat. Pesticides were extracted from samples with acetonitrile/n-hexane (v :v, 1:1). The analytical screening was performed by gas chromatography coupled with electron-capture detection (ECD). The identification of compounds was based on their retention time and on comparison of the primary and secondary ions. The optimized method was validated by determining accuracy (recovery percentages), precision (repeatability and reproducibility), and sensitivity (detection and quantitation limits) from analyses of samples fortified at 38 to 300 ng/g levels. Correlation coefficients for the 22 extracted pesticide standard curves (linear regression analysis, n = 3) ranged from 0.998 to 1.000. Recovery studies from 2 g samples fortified at 3 levels demonstrated that the GC-ECD method provides 64.4-96.0% recovery for all pesticides except 2,4′-DDE (44.6-50.4%), 4,4′-DDE (51.1-57.5%) and 2,4′-DDT (50.0-51.2%). Both repeatability and reproducibility relative standard deviation values were < 20% for all residues. Detection limits ranged from 0.31 to 1.27 ng/g and quantification limits were between 1.04 and 4.25 ng/g. The proposed analytical method may be used as a simple procedure in routine determinations of OCs and Ops in meat. It can also be applied to the determination of pesticide multi-residues in other animal products such as butter and milk.

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