scholarly journals Correction: Corrigendum: An interactive web-based application for Comprehensive Analysis of RNAi-screen Data

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Bhaskar Dutta ◽  
Alaleh Azhir ◽  
Louis-Henri Merino ◽  
Yongjian Guo ◽  
Swetha Revanur ◽  
...  
2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Bhaskar Dutta ◽  
Alaleh Azhir ◽  
Louis-Henri Merino ◽  
Yongjian Guo ◽  
Swetha Revanur ◽  
...  

Abstract RNAi screens are widely used in functional genomics. Although the screen data can be susceptible to a number of experimental biases, many of these can be corrected by computational analysis. For this purpose, here we have developed a web-based platform for integrated analysis and visualization of RNAi screen data named CARD (for Comprehensive Analysis of RNAi Data; available at https://card.niaid.nih.gov). CARD allows the user to seamlessly carry out sequential steps in a rigorous data analysis workflow, including normalization, off-target analysis, integration of gene expression data, optimal thresholds for hit selection and network/pathway analysis. To evaluate the utility of CARD, we describe analysis of three genome-scale siRNA screens and demonstrate: (i) a significant increase both in selection of subsequently validated hits and in rejection of false positives, (ii) an increased overlap of hits from independent screens of the same biology and (iii) insight to microRNA (miRNA) activity based on siRNA seed enrichment.


Data Mining plays an important role in the Business world and it helps the educational institution to predict and make decisions related to the students’ academic status. From a large volume of data in educational databases it is difficult to predict student performance. In India currently the existing systems lack in monitoring and analyzing the students’ performance. The main reason is that the existing system has insufficient capabilities for identification of performance of the student and it also not considered all factors that affect the achievements of a student’s in the context of India. Therefore, a systematical literature review on predicting student performance by the proposed system is a web-based which makes use of the mining techniques for the extraction of useful information. This work is digging insight into the state-based and eventbased approaches for predicting student performance. A Comparative analysis is conducted to suggest regression-based algorithms of state-based framework lack accuracy and correlation-based algorithms under the event-driven approach outperform classical regression algorithms. It is also concluded from pedagogical a point of view, higher engagement with social media leads to higher final grades


2004 ◽  
Vol 32 (Web Server) ◽  
pp. W595-W601 ◽  
Author(s):  
G. Neshich ◽  
W. Rocchia ◽  
A. L. Mancini ◽  
M. E. B. Yamagishi ◽  
P. R. Kuser ◽  
...  

Author(s):  
Stelios Rozakis

Biomass-to-energy projects have become attractive these days because of recent European policy measures that attempt to address acute environmental, agricultural and energy challenges accumulated during the last 30 years. Bio-energy issues constitute spatially dependent problems by definition due to the state-of-the-art technology and the bulky nature of biomass. Moreover, biomass profitability is linked to the structure and perspectives of the arable cropping systems since these are able to supply considerable quantities in the short and medium term required to fulfil the ambitious targets aimed at by policy makers. Therefore, appropriate tools are necessary to enable a comprehensive analysis and support decisions of policy makers, industry, researchers and farmers. Spatial Decision Support Systems that have been developed to support bio-energy decisions are used as a basis enhanced by a web-based interface, in this exercise resulting in a Web-SDSS. This tool is implemented in Thessaly, the most significant arable cropping region in Greece, in order to evaluate selected energy crop supply. The methodology and architecture of this tool are detailed in this paper, followed by an illustrative description of its operational version implemented in ex-tobacco producing areas.


2011 ◽  
Vol 135 (3) ◽  
pp. 379-383
Author(s):  
Artur Zembowicz ◽  
Adeel Ahmad ◽  
Stephen R Lyle

Abstract Context.—Sharing cases and seeking second opinion consultations is an important part of everyday pathology practice. Internet-based communications and upcoming digital slide technologies have the potential to decrease barriers and open access to the best expertise. We recently developed a dedicated Web-based process for communication with outside practices seeking second opinion consultations. The software allowed us to collect data about the current needs and use of a second opinion consultation practice, a topic that has not been addressed in research studies thus far. Objective.—To analyze the needs for and performance of a Web-based second opinion consultation practice in dermatopathology. Design.—We performed a retrospective analysis on paper and digital records. Results.—The average turn-around time from the time of biopsy to the time the report was issued was 7 days. Eighty-two percent of cases were reported the same day they were received. Biopsies of melanocytic lesions, inflammatory dermatoses, and squamous lesions comprised 82% of consultations. Among the remaining cases, soft tissue tumors, adnexal neoplasms, alopecia, and nonmelanoma nonsquamous lesions were the most common diagnoses. In 69% of cases, the outside report contained information about the diagnosis favored by the submitting pathologists. In 5%, there was a significant change in the diagnosis. Conclusions.—Web-based communication facilitates rapid turn-around time and reduces costs and barriers to second opinion consultation.


1998 ◽  
Vol 62 (9) ◽  
pp. 671-674
Author(s):  
JF Chaves ◽  
JA Chaves ◽  
MS Lantz
Keyword(s):  

2013 ◽  
Vol 23 (3) ◽  
pp. 82-87 ◽  
Author(s):  
Eva van Leer

Mobile tools are increasingly available to help individuals monitor their progress toward health behavior goals. Commonly known commercial products for health and fitness self-monitoring include wearable devices such as the Fitbit© and Nike + Pedometer© that work independently or in conjunction with mobile platforms (e.g., smartphones, media players) as well as web-based interfaces. These tools track and graph exercise behavior, provide motivational messages, offer health-related information, and allow users to share their accomplishments via social media. Approximately 2 million software programs or “apps” have been designed for mobile platforms (Pure Oxygen Mobile, 2013), many of which are health-related. The development of mobile health devices and applications is advancing so quickly that the Food and Drug Administration issued a Guidance statement with the purpose of defining mobile medical applications and describing a tailored approach to their regulation.


2008 ◽  
Vol 41 (8) ◽  
pp. 23
Author(s):  
MITCHEL L. ZOLER
Keyword(s):  

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