scholarly journals New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Yingchang Lu ◽  
Felix R. Day ◽  
Stefan Gustafsson ◽  
Martin L. Buchkovich ◽  
Jianbo Na ◽  
...  
2003 ◽  
Vol 35 (Supplement 1) ◽  
pp. S279
Author(s):  
K Martin ◽  
J S. Green ◽  
J W. Womack ◽  
K L. Hill ◽  
K Meyer ◽  
...  

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 366-366
Author(s):  
Martin Jr Rosas ◽  
Sherry Pinneo ◽  
Celeste O'Mealy ◽  
Changqi Liu ◽  
Mark Kern ◽  
...  

Abstract Objectives Mangos contain many beneficial dietary compounds including vitamins, minerals, fiber, and are a unique source of certain polyphenols such as mangiferin. Accumulating evidence from in vitro and animal studies have demonstrated that mangos may have antidiabetic, anti-inflammatory, and cardioprotective properties. However, the effects of fresh mango consumption in humans are less clear. The objective of this study was to examine the effects of fresh mango consumption compared to an isocaloric snack (low-fat cookies) on body weight, body fat, blood pressure, glucose, insulin, lipid profiles, liver function enzymes, inflammation, and antioxidant activity in overweight and obese adults. Methods In a randomized crossover design, 27 overweight and obese adults (11 females, 16 males, age 26 ± 8.1 years) consumed 100 Kcal of fresh mangos (166g) or isocaloric low-fat cookies (24g) daily for 12 weeks. Following an overnight fast, a venous blood draw was taken at baseline, week 4, and week 12. Blood samples were analyzed for glucose, insulin, lipid profiles, liver function enzymes, C-reactive protein (CRP), and total antioxidant capacity (TAC). At each visit, body weight, body fat percentage, and blood pressure were measured. Results Twelve weeks of daily mango consumption significantly decreased blood glucose, CRP, and aspartate transaminase (AST) activity while TAC significantly increased (P < 0.05). There were no significant changes in body weight, body fat percentage, blood pressure, insulin, lipid profile, or other liver function enzymes following mango consumption. Cookie consumption significantly increased insulin, CRP, and triglycerides (P < 0.05). Conclusions Mango consumption improved certain chronic disease risk factors including reductions in fasting glucose and inflammation while lipid profiles and anthropometric measurements were not affected. These results suggest that relative to the control snack, daily mango consumption may improve certain risk factors associated with overweight and obesity and should be considered for future research as they contain unique bioactive compounds. Funding Sources This study was funded by the National Mango Board.


FACETS ◽  
2017 ◽  
Vol 2 (1) ◽  
pp. 53-67 ◽  
Author(s):  
Taylor W. Rowley ◽  
Jennifer L. Espinoza ◽  
Jeremy D. Akers ◽  
David L. Wenos ◽  
Elizabeth S. Edwards

This study examined the effects of a 12 week, treadmill-based, run sprint interval training (SIT) protocol compared with that of a moderate-intensity continuous training (MICT) protocol in healthy, inactive, overweight/obese women, on cardiovascular disease risk factors. After random assignment, the SIT group completed 4–10 × 30 s maximal sprints, with a 4 min active recovery between sprints, and the MICT group completed 30–60 min at moderate intensity (45–55% heart rate reserve (HRR)). The rate of perceived exertion (RPE) was recorded for each session, and perceived enjoyment was quantified every 3 weeks. Clinical and fitness testing were completed at baseline, 6 weeks, and 12 weeks. Twelve female participants (age: 34.1 ± 6.1; body mass index (BMI): 31.3 ± 6.8; VO2peak: 27.0 ± 6.2) completed the intervention. There were significant main effects for time for VO2peak ( p = 0.001), body fat percentage ( p = 0.001), and session RPE ( p = 0.006). VO2peak improved 20.7% in the SIT group ( n = 5) and 24.4% in the MICT group ( n = 7). Body fat percentage reduced by 1.7% in the SIT group and 2.6% in the MICT group. Perceived enjoyment was similarly high between the groups despite higher session RPE in the SIT group ( p = 0.441). SIT training on a motor-driven treadmill elicits similar improvements in oxygen utilization and body composition as moderate-intensity training in this population.


2020 ◽  
Vol 3 ◽  
pp. 29-34
Author(s):  
Hosein Sheibani ◽  
Maryam Saberi-Karimian ◽  
Habibollah Esmaily ◽  
Mohsen Mouhebati ◽  
Mohmoud Reza Azarpazhooh ◽  
...  

Author(s):  
Ali Ozkan ◽  
Mutlu Turkmen ◽  
Taner Bozkus ◽  
Murat Kul ◽  
Recep Soslu ◽  
...  

The purpose of the present study was to determine the relationship between healthy lifestyle behaviors, physical fitness and coronary risk factors in university students. 320 male and female (nm:171; nf:149) students from a university participated in this study voluntarily. For the determination of body composition and Body Mass Indexes (BMI), subjects’ height, body weight, and skinfold thickness were taken and body fat percentage (%Fat) was determined. Healthy lifestyle behaviors were determined using the healthy lifestyle behaviors questionnaire. Indicators of physical fitness included flexibility (sit-up) (F), muscle strength and endurance (isometric knee (KS), back strength (BS) and a total of shuttle (TS), sprint performance, BMI, and body fat percentage (%fat). Coronary heart disease risk factors included mean arterial blood pressure (systolic (SBP) and diastolic (DBP)), fasting blood levels of triglycerides (TG), total cholesterol (TC), hematocrit (HT), and hemoglobin (HM). Results indicated subjects have normal body mass index, body fat percentage, SBP, DBP, TG, TCF, BS, KS. The results of the Pearson Product Moment Correlation Analysis, indicated that SBP, DBP, TG, TCF, BS, KS for male and female was significantly correlated with flexibility (sit-up) (F), muscle strength and endurance (isometric knee (KS), back strength (BS) and total of shuttle (TS)), sprint performance. (p<0.01; p<0.05), In conclusion, the findings of the present study indicated that physical fitness and healthy lifestyle behaviors play a determinant role in coronary heart disease risk factors for male and female students from a university.


2020 ◽  
Vol 8 (B) ◽  
pp. 191-194
Author(s):  
Yuniar Lestari ◽  
Delmi Sulastri ◽  
Desmawati Desmawati

Background: Cardiometabolic disease risk is increasing in the premenopausal phase of women life. This study aims to relationship body fat percentage with the modifiable risk factors of cardiometabolic disease in Minangkabau premenopausal people. Methods: A cross-sectional study was conducted in 111 Minangkabau premenopausal people, aged 40 – 55 years old at Padang City in West Sumatera, Indonesia. Body fat percentage analyzed by Bioelectrical Impedance Analyzer (BIA). Fasting blood glucose and lipid profile was examined from venous blood. Data were analyzed by using a Rank-Spearman correlation test with significant levels p<0.05. Results:Average body fat percentage of subjects 36.23 ± 6.9, fasting blood glucose 101.52 ± 12.3 mg/dL; total cholesterol 193.99±41.5 mg/dL; triglyceride 113.76±37.9 mg/dL mg/dL; LDL-cholesterol 120.59±45.7 mg/dL and HDL-cholesterol 53.52±15.6 mg/dL. Body fat percentage has a significant correlation with triglyceride (r=0.368; p=0.001), and HDL-cholesterol levels (r=-0.307; p=0.006 ) just in subject with polymorphism, but does not have a significant correlation with another biomarker. Conclusion: Body fat percentage correlates with triglyceride and HDL cholesterol in Minangkabau premenopausal women who have polymorphism of TERT Gene. BACKGROUND: Cardiometabolic disease risk is increasing in the premenopausal phase of women life. The telomerase reverse transcriptase (TERT) gene is a gene that plays a role in protecting telomeres from progressive shortening. Telomere shortening is associated with the incidence of cardiometabolic disease. AIM: This study aims to elucidate the relationship body fat percentage with the modifiable risk factors of cardiometabolic disease in Minangkabau premenopausal people. METHODS: A cross-sectional study was conducted in 111 Minangkabau premenopausal people aged 40–55 years old at Padang City in West Sumatera, Indonesia. Body fat percentage analyzed by bioelectrical impedance analyzer. Fasting blood glucose and lipid profile were examined from venous blood. Polymorphism of the TERT rs2736098 gene was analyzed by a polymerase chain reaction. Data were analyzed using Spearman’s rank correlation test with significant levels p < 0.05. RESULTS: Average body fat percentage of subjects was 36.23 ± 6.9, fasting blood glucose was 101.52 ± 12.3 mg/dL; total cholesterol was 193.99 ± 41.5 mg/dL; triglyceride was 113.76 ± 37.9 mg/dL; LDL-cholesterol was 120.59 ± 45.7 mg/dL and HDL-cholesterol was 53.52±15.6 mg/dL. Body fat percentage has a significant correlation with triglyceride (r = 0.368; p = 0.001) and HDL-cholesterol levels (r = −0.307; p = 0.006) just in subject with polymorphism but does not have a significant correlation with another biomarker. CONCLUSION: Body fat percentage correlates with triglyceride and HDL cholesterol in Minangkabau premenopausal women who have polymorphism of TERT gene.


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1675-P
Author(s):  
XIAO TAN ◽  
CHRISTIAN BENEDICT

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