Osteogenic transcription factor Runx2 is a maternal determinant of dorsoventral patterning in zebrafish

2008 ◽  
Vol 10 (3) ◽  
pp. 346-352 ◽  
Author(s):  
Maria Vega C. Flores ◽  
Enid Yi Ni Lam ◽  
Kathryn E. Crosier ◽  
Philip S. Crosier
Keyword(s):  
Transcription Factor ◽  
Dorsoventral Patterning

scholarly journals RFX4 transcription factor regulates IFT172 expression, cilia formation and dorsoventral patterning of the central nervous system

2007 ◽  
Vol 306 (1) ◽  
pp. 360
Author(s):  
Amir M. Ashique ◽  
Mattias Karlen ◽  
Youngshik Choe ◽  
Johan Ericson ◽  
John L. Rubenstein ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Transcription Factor ◽  
Dorsoventral Patterning ◽  
Cilia Formation ◽  
The Central Nervous System

pannier acts upstream of wingless to direct dorsal eye disc development in Drosophila

Development ◽  
2000 ◽  
Vol 127 (5) ◽  
pp. 1007-1016 ◽  
Author(s):  
C. Maurel-Zaffran ◽  
J.E. Treisman
Keyword(s):  
Transcription Factor ◽  
Boundary Region ◽  
Dorsal Margin ◽  
Secreted Protein ◽  
Dorsoventral Patterning ◽  
Eye Disc ◽  
Eye Field ◽  
Upstream Element ◽  
Dorsoventral Boundary ◽  
Gata Family

The dorsoventral midline of the Drosophila eye disc is a source of signals that stimulate growth of the eye disc, define the point at which differentiation initiates, and direct ommatidial rotation in opposite directions in the two halves of the eye disc. This boundary region seems to be established by the genes of the iroquois complex, which are expressed in the dorsal half of the disc and inhibit fringe expression there. Fringe controls the activation of Notch and the expression of its ligands, with the result that Notch is activated only at the fringe expression boundary at the midline. The secreted protein Wingless activates the dorsal expression of the iroquois genes. We show here that pannier, which encodes a GATA family transcription factor expressed at the dorsal margin of the eye disc from embryonic stages on, acts upstream of wingless to control mirror and fringe expression and establish the dorsoventral boundary. Loss of pannier function leads to the formation of an ectopic eye field and the reorganization of ommatidial polarity, and ubiquitous pannier expression can abolish the eye field. Pannier is thus the most upstream element yet described in dorsoventral patterning of the eye disc.

scholarly journals Pou2, a class V POU-type transcription factor in zebrafish, regulates dorsoventral patterning and convergent extension movement at different blastula stages

2012 ◽  
Vol 129 (9-12) ◽  
pp. 219-235 ◽  
Author(s):  
Alam Khan ◽  
Andrew Nakamoto ◽  
Shun Okamoto ◽  
Miyako Tai ◽  
Yukiko Nakayama ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Convergent Extension ◽  
Dorsoventral Patterning ◽  
Class V

Transcription factor/DNA interactions visualized by electron spectroscopic imaging

1992 ◽  
Vol 50 (1) ◽  
pp. 450-451
Author(s):  
David P. Bazett-Jones ◽  
Mark L. Brown
Keyword(s):  
Transcription Factor ◽  
Dna Sequences ◽  
Transcription Initiation ◽  
Molecular Mechanisms ◽  
Phosphorus Content ◽  
Spectroscopic Imaging ◽  
Electron Spectroscopic Imaging ◽  
Dna Backbone ◽  
Two Parameters ◽  
High Level

A multisubunit RNA polymerase enzyme is ultimately responsible for transcription initiation and elongation of RNA, but recognition of the proper start site by the enzyme is regulated by general, temporal and gene-specific trans-factors interacting at promoter and enhancer DNA sequences. To understand the molecular mechanisms which precisely regulate the transcription initiation event, it is crucial to elucidate the structure of the transcription factor/DNA complexes involved. Electron spectroscopic imaging (ESI) provides the opportunity to visualize individual DNA molecules. Enhancement of DNA contrast with ESI is accomplished by imaging with electrons that have interacted with inner shell electrons of phosphorus in the DNA backbone. Phosphorus detection at this intermediately high level of resolution (≈lnm) permits selective imaging of the DNA, to determine whether the protein factors compact, bend or wrap the DNA. Simultaneously, mass analysis and phosphorus content can be measured quantitatively, using adjacent DNA or tobacco mosaic virus (TMV) as mass and phosphorus standards. These two parameters provide stoichiometric information relating the ratios of protein:DNA content.

The role of transcription factor Egr‐1 in IL‐1 up‐regulation of tubular CD44 expression

Nephrology ◽  
2000 ◽  
Vol 5 (3) ◽  
pp. A92-A92
Author(s):  
Takazoe K ◽  
Foti R ◽  
Hurst La ◽  
Atkins Rc ◽  
Nikolic‐Paterson DJ.
Keyword(s):  
Transcription Factor ◽  
Cd44 Expression

Alpha-fetoprotein producing gastric cancer cells lack transcription factor AT-motif binding factor 1 (ATBF1)

2001 ◽  
Vol 120 (5) ◽  
pp. A31-A31
Author(s):  
H KATAOKA ◽  
T JOH ◽  
T OHSHIMA ◽  
Y ITOH ◽  
K SENOO ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Transcription Factor ◽  
Cancer Cells ◽  
Alpha Fetoprotein ◽  
Gastric Cancer Cells ◽  
Binding Factor
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