scholarly journals Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data

2008 ◽  
Vol 27 (1) ◽  
pp. 51-57 ◽  
Author(s):  
W Nicholson Price II ◽  
Yang Chen ◽  
Samuel K Handelman ◽  
Helen Neely ◽  
Philip Manor ◽  
...  
Keyword(s):  
Experimental Data ◽  
Physical Properties ◽  
Large Scale ◽  
Protein Crystallization ◽  
Control Protein

scholarly journals A study of computational methods for wake structure and base pressure prediction of a generic SUV model with fixed and rotating wheels

2017 ◽  
Vol 231 (9) ◽  
pp. 1222-1238 ◽  
Author(s):  
David Forbes ◽  
Gary Page ◽  
Martin Passmore ◽  
Adrian Gaylard
Keyword(s):  
Experimental Data ◽  
Computational Methods ◽  
Large Scale ◽  
Ground Plane ◽  
Computational Cost ◽  
Rear Wheel ◽  
Base Pressure ◽  
Detached Eddy Simulation ◽  
Wake Structure ◽  
Wake Interactions

This study is an evaluation of the computational methods in reproducing experimental data for a generic sports utility vehicle (SUV) geometry and an assessment on the influence of fixed and rotating wheels for this geometry. Initially, comparisons are made in the wake structure and base pressures between several CFD codes and experimental data. It was shown that steady-state RANS methods are unsuitable for this geometry due to a large scale unsteadiness in the wake caused by separation at the sharp trailing edge and rear wheel wake interactions. unsteady RANS (URANS) offered no improvements in wake prediction despite a significant increase in computational cost. The detached-eddy simulation (DES) and Lattice–Boltzmann methods showed the best agreement with the experimental results in both the wake structure and base pressure, with LBM running in approximately a fifth of the time for DES. The study then continues by analysing the influence of rotating wheels and a moving ground plane over a fixed wheel and ground plane arrangement. The introduction of wheel rotation and a moving ground was shown to increase the base pressure and reduce the drag acting on the vehicle when compared to the fixed case. However, when compared to the experimental standoff case, variations in drag and lift coefficients were minimal but misleading, as significant variations to the surface pressures were present.

Investigation on hydrodynamic forces leading to coarse particle entrainment using Large-Eddy Simulations

2021 ◽  
Author(s):  
Gaston Latessa ◽  
Angela Busse ◽  
Manousos Valyrakis
Keyword(s):  
Experimental Data ◽  
Flow Field ◽  
Large Scale ◽  
Large Eddy Simulations ◽  
Flow Conditions ◽  
Mean Flow ◽  
Protection Measures ◽  
Practical Applications ◽  
Particle Entrainment ◽  
Large Eddy

<p>The prediction of particle motion in a fluid flow environment presents several challenges from the quantification of the forces exerted by the fluid onto the solids -normally with fluctuating behaviour due to turbulence- and the definition of the potential particle entrainment from these actions. An accurate description of these phenomena has many practical applications in local scour definition and to the design of protection measures.</p><p>In the present work, the actions of different flow conditions on sediment particles is investigated with the aim to translate these effects into particle entrainment identification through analytical solid dynamic equations.</p><p>Large Eddy Simulations (LES) are an increasingly practical tool that provide an accurate representation of both the mean flow field and the large-scale turbulent fluctuations. For the present case, the forces exerted by the flow are integrated over the surface of a stationary particle in the streamwise (drag) and vertical (lift) directions, together with the torques around the particle’s centre of mass. These forces are validated against experimental data under the same bed and flow conditions.</p><p>The forces are then compared against threshold values, obtained through theoretical equations of simple motions such as rolling without sliding. Thus, the frequency of entrainment is related to the different flow conditions in good agreement with results from experimental sediment entrainment research.</p><p>A thorough monitoring of the velocity flow field on several locations is carried out to determine the relationships between velocity time series at several locations around the particle and the forces acting on its surface. These results a relevant to determine ideal locations for flow investigation both in numerical and physical experiments.</p><p>Through numerical experiments, a large number of flow conditions were simulated obtaining a full set of actions over a fixed particle sitting on a smooth bed. These actions were translated into potential particle entrainment events and validated against experimental data. Future work will present the coupling of these LES models with Discrete Element Method (DEM) models to verify the entrainment phenomena entirely from a numerical perspective.</p>

Thermal Laser Separation – A Novel Dicing Technology Fulfilling the Demands of Volume Manufacturing of 4H-SiC Devices

2015 ◽  
Vol 821-823 ◽  
pp. 528-532 ◽  
Author(s):  
Dirk Lewke ◽  
Karl Otto Dohnke ◽  
Hans Ulrich Zühlke ◽  
Mercedes Cerezuela Barret ◽  
Martin Schellenberger ◽  
...  
Keyword(s):  
Experimental Data ◽  
Process Control ◽  
Tool Wear ◽  
Large Scale ◽  
State Of The Art ◽  
Scale Production ◽  
High Quality ◽  
Large Scale Production ◽  
Laser Separation

One challenge for volume manufacturing of 4H-SiC devices is the state-of-the-art wafer dicing technology – the mechanical blade dicing which suffers from high tool wear and low feed rates. In this paper we discuss Thermal Laser Separation (TLS) as a novel dicing technology for large scale production of SiC devices. We compare the latest TLS experimental data resulting from fully processed 4H-SiC wafers with results obtained by mechanical dicing technology. Especially typical product relevant features like process control monitoring (PCM) structures and backside metallization, quality of diced SiC-devices as well as productivity are considered. It could be shown that with feed rates up to two orders of magnitude higher than state-of-the-art, no tool wear and high quality of diced chips, TLS has a very promising potential to fulfill the demands of volume manufacturing of 4H-SiC devices.

scholarly journals Large-scale evaluation of protein reductive methylation for improving protein crystallization

2008 ◽  
Vol 5 (10) ◽  
pp. 853-854 ◽  
Author(s):  
Youngchang Kim ◽  
Pearl Quartey ◽  
Hui Li ◽  
Lour Volkart ◽  
Catherine Hatzos ◽  
...  
Keyword(s):  
Large Scale ◽  
Protein Crystallization ◽  
Reductive Methylation ◽  
Scale Evaluation

scholarly journals The Physical Properties of Large Scale Systems from Optical Observations

1978 ◽  
Vol 79 ◽  
pp. 253-262
Author(s):  
G. O. Abell
Keyword(s):  
Physical Properties ◽  
Large Scale ◽  
Local Group ◽  
Optical Observations ◽  
Local Inhomogeneity ◽  
Large Scale Systems ◽  
Local Supercluster

Holmberg's (1937) analysis of the distribution of double and multiple galaxies provided what may have been the first hint of a local inhomogeneity of greater scale than that of the Local Group. the idea of a Local Supercluster was subsequently revived by de Vaucouleurs (1953, 1956, 1958). the analyses of others, as well as the continuing study of de Vaucouleurs himself (1976 and references cited therein) have now effectively established the reality of the Local Supercluster. Several other more remote inhomogeneities, or “clouds” of galaxies, were described by Shane and Wirtanen (1954). the writer (Abell 1958) found the distribution of rich clusters to be clumpy, and published a finding list of several apparent superclusters (Abell 1961).

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