scholarly journals Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Nature ◽  
2010 ◽  
Vol 463 (7282) ◽  
pp. 808-812 ◽  
Author(s):  
Ye Zheng ◽  
Steven Josefowicz ◽  
Ashutosh Chaudhry ◽  
Xiao P. Peng ◽  
Katherine Forbush ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Fate ◽  
Regulatory T Cell ◽  
Foxp3 Gene ◽  
Dna Elements

Dichotomous role of TGF-β controls inducible regulatory T-cell fate in allergic airway disease through Smad3 and TGF-β–activated kinase 1

2020 ◽  
Vol 145 (3) ◽  
pp. 933-946.e4
Author(s):  
Anthony Joetham ◽  
Michaela Schedel ◽  
Fangkun Ning ◽  
Meiqin Wang ◽  
Katsuyuki Takeda ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Fate ◽  
Regulatory T Cell ◽  
Airway Disease ◽  
Allergic Airway Disease

scholarly journals Role of Macrophage Migration Inhibitory Factor in the Regulatory T Cell Response of Tumor-Bearing Mice

2012 ◽  
Vol 189 (8) ◽  
pp. 3905-3913 ◽  
Author(s):  
Susanna Choi ◽  
Hang-Rae Kim ◽  
Lin Leng ◽  
Insoo Kang ◽  
William L. Jorgensen ◽  
...  
Keyword(s):  
T Cell ◽  
Migration Inhibitory Factor ◽  
Regulatory T Cell ◽  
Cell Response ◽  
Macrophage Migration Inhibitory Factor ◽  
T Cell Response ◽  
Inhibitory Factor ◽  
Macrophage Migration ◽  
Tumor Bearing

scholarly journals Unexpected Regulatory Role of CCR9 in Regulatory T Cell Development

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0134100 ◽  
Author(s):  
Heather L. Evans-Marin ◽  
Anthony T. Cao ◽  
Suxia Yao ◽  
Feidi Chen ◽  
Chong He ◽  
...  
Keyword(s):  
T Cell ◽  
Regulatory T Cell ◽  
T Cell Development ◽  
Cell Development ◽  
Regulatory Role

scholarly journals Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Mark Engel ◽  
Tom Sidwell ◽  
Ajithkumar Vasanthakumar ◽  
George Grigoriadis ◽  
Ashish Banerjee
Keyword(s):  
T Cells ◽  
Transcription Factors ◽  
T Cell ◽  
Regulatory T Cells ◽  
Immune Tolerance ◽  
Regulatory T Cell ◽  
T Cell Development ◽  
Signalling Pathways ◽  
Treg Development

Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.

Differentiating role of B7-CD28/CTLA-4 interaction in the induction of mucosal inflammation and regulatory T cell functions in chronic experimental colitis

2001 ◽  
Vol 120 (5) ◽  
pp. A46-A47
Author(s):  
Zhanju Liu ◽  
Univ Hosp Gasthuisberg ◽  
Philippe Maerten ◽  
Stefaan Colpaert ◽  
Jan L. Ceuppens ◽  
...  
Keyword(s):  
T Cell ◽  
Regulatory T Cell ◽  
Experimental Colitis ◽  
Mucosal Inflammation ◽  
Cell Functions

scholarly journals Increased T Cell Autoreactivity in the Absence of CD40-CD40 Ligand Interactions: A Role of CD40 in Regulatory T Cell Development

2001 ◽  
Vol 166 (1) ◽  
pp. 353-360 ◽  
Author(s):  
Atsushi Kumanogoh ◽  
Xiaosong Wang ◽  
Ihnsook Lee ◽  
Chie Watanabe ◽  
Masahito Kamanaka ◽  
...  
Keyword(s):  
T Cell ◽  
Regulatory T Cell ◽  
T Cell Development ◽  
Cd40 Ligand ◽  
Cell Development ◽  
Ligand Interactions
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