Total synthesis of marine natural products without using protecting groups

Nature ◽  
2007 ◽  
Vol 446 (7134) ◽  
pp. 404-408 ◽  
Author(s):  
Phil S. Baran ◽  
Thomas J. Maimone ◽  
Jeremy M. Richter
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Marine Natural Products ◽  
Protecting Groups

Total synthesis of marine natural products separacenes A and B

2017 ◽  
Vol 15 (22) ◽  
pp. 4842-4850 ◽  
Author(s):  
Subhendu Das ◽  
Rajib Kumar Goswami
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Marine Natural Products

Total synthesis of the potent antifungal agents bengazole C and E

2009 ◽  
Vol 74 (6) ◽  
pp. 887-900 ◽  
Author(s):  
Álvaro Enríquez-García ◽  
Steven V. Ley
Keyword(s):  
Natural Products ◽  
Antifungal Activity ◽  
Total Synthesis ◽  
Marine Natural Products ◽  
Antifungal Agents ◽  
Nitrile Oxide ◽  
Total Syntheses ◽  
Unique Structure

The bengazoles are marine natural products with unique structure, containing two oxazole rings flanking a single carbon. They show very potent antifungal activity. The total syntheses of bengazole C and E are described following a convergent route which involves diastereoselective cycloaddition of an appropriately substituted nitrile oxide with a butane-1,2-diacetal-protected alkenediol as the key step.

ChemInform Abstract: MARINE NATURAL PRODUCTS FROM THE ATLANTIC ZONE. PART 27. TOTAL SYNTHESIS OF OBTUSENOL

1982 ◽  
Vol 13 (13) ◽  
Author(s):  
A. G. GONZALEZ ◽  
J. D. MARTIN ◽  
C. PEREZ ◽  
M. A. RAMIREZ ◽  
F. RAVELO
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Marine Natural Products

Protecting-group-free synthesis of haterumadienone- and puupehenone-type marine natural products

2017 ◽  
Vol 19 (9) ◽  
pp. 2140-2144 ◽  
Author(s):  
Hong-Shuang Wang ◽  
Hui-Jing Li ◽  
Jun-Li Wang ◽  
Yan-Chao Wu
Keyword(s):  
Natural Products ◽  
Transition Metals ◽  
Marine Natural Products ◽  
Protecting Groups ◽  
Protecting Group

The atom- and step-economical synthesis of seven puupehenone- and haterumadienone-type marine natural products without the use of protecting groups and transition metals has been achieved from the abundant feedstock chemical sclareolide in only 6 to 9 steps.

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