scholarly journals Systemic Therapy of Disseminated Myeloma in Passively Immunized Mice Using Measles Virus-infected Cell Carriers

2010 ◽  
Vol 18 (6) ◽  
pp. 1155-1164 ◽  
Author(s):  
Chunsheng Liu ◽  
Stephen J Russell ◽  
Kah-Whye Peng
Keyword(s):  
Infected Cell ◽  
Systemic Therapy ◽  
Measles Virus ◽  
Virus Infected Cell ◽  
Cell Carriers

Mapping of the major histocompatibility complex and viral antigens on the plasma membrane of a measles virus-infected cell

Virology ◽  
1983 ◽  
Vol 127 (2) ◽  
pp. 426-437 ◽  
Author(s):  
Michael B.A. Oldstone ◽  
Robert S. Fujinami ◽  
Antoinette Tishon ◽  
David Finney ◽  
Henry C. Powell ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Major Histocompatibility Complex ◽  
Infected Cell ◽  
Measles Virus ◽  
Major Histocompatibility ◽  
Virus Infected Cell ◽  
Viral Antigens ◽  
Histocompatibility Complex

scholarly journals 58. Oncolytic Measles Virus Delivery by Infected Cell Carriers–A Strategy To “By-Pass” the Pre-Existing Humoral Immune Response

2006 ◽  
Vol 13 ◽  
pp. S24-S25
Author(s):  
Ianko D. Iankov ◽  
Boris R.A. Blechacz ◽  
Guy E. Griesmann ◽  
Mark J. Federspiel ◽  
Stephen J. Russell
Keyword(s):  
Immune Response ◽  
Infected Cell ◽  
Humoral Immune Response ◽  
Measles Virus ◽  
Humoral Immune ◽  
Virus Delivery ◽  
Cell Carriers

scholarly journals Lysis of measles virus-infected cells by the purified cytolytic alternative complement pathway and antibody.

1979 ◽  
Vol 150 (3) ◽  
pp. 445-454 ◽  
Author(s):  
J G Patrick Sissons ◽  
R D Schreiber ◽  
L H Perrin ◽  
N R Cooper ◽  
H J Müller-Eberhard ◽  
...  
Keyword(s):  
Infected Cell ◽  
Human Serum ◽  
Serum Protein ◽  
Hela Cells ◽  
Measles Virus ◽  
Alternative Pathway ◽  
Complement Pathway ◽  
Virus Infected Cell ◽  
Alternative Complement ◽  
Infected Cells

The dependence of antibody-and-complement-mediated lysis of virus-infected cells on the alternative pathway was examined utilizing the isolated cytolytic alternative pathway--a system consisting of the six purified proteins of the alternative pathway of activation (C3, factors B and D, beta 1H, C3b inactivator and properdin), and the five proteins of the membrane attack pathway (C5--9) of complement. HeLa cells acutely infected with measles virus were lysed by anti-viral IgG and the isolated cytolytic alternative pathway with an efficiency comparable to whole human serum. IgG and its F(ab')2 fragment were equally effective in inducing lysis by the isolated cytolytic alternative pathway, binding of approximately equal to 5 X 10(7) molecules per cell being required for 50% lysis; in contrast, no lysis occurred when equivalen or greater amounts of Fab' were bound to the virus-infected cell. Properdin was required for lysis. No lysis occurred if properdin was deleted from the isolated cytolytic alternative pathway, and lysis was diminished by 80% in properdin-depleted serum. Uptake of [125I]C3b from the isolated alternative pathway onto measles virus-infected cells occurred in the absence of properdin, but was accelerated in the presence of properdin. The 11 proteins of the isolated cytolytic alternative pathway are thus sufficient for lysis of measles virus-infected cells bearing anti-viral IgG or F(ab')2 without any other serum protein.

scholarly journals ABC294640, A Novel Sphingosine Kinase 2 Inhibitor, Induces Oncogenic Virus–Infected Cell Autophagic Death and Represses Tumor Growth

2017 ◽  
Vol 16 (12) ◽  
pp. 2724-2734 ◽  
Author(s):  
Lu Dai ◽  
Aiping Bai ◽  
Charles D. Smith ◽  
Paulo C. Rodriguez ◽  
Fangyou Yu ◽  
...  
Keyword(s):  
Infected Cell ◽  
Tumor Growth ◽  
Sphingosine Kinase ◽  
Oncogenic Virus ◽  
Virus Infected Cell ◽  
Sphingosine Kinase 2

scholarly journals Infected Cell Carriers: A New Strategy for Systemic Delivery of Oncolytic Measles Viruses in Cancer Virotherapy

2007 ◽  
Vol 15 (1) ◽  
pp. 114-122 ◽  
Author(s):  
Ianko D Iankov ◽  
Boris Blechacz ◽  
Chunsheng Liu ◽  
Jeffrey D Schmeckpeper ◽  
James E Tarara ◽  
...  
Keyword(s):  
Infected Cell ◽  
Systemic Delivery ◽  
New Strategy ◽  
Cell Carriers
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