Bone-protective Effects of Nonviral Gene Therapy With Folate–Chitosan DNA Nanoparticle Containing Interleukin-1 Receptor Antagonist Gene in Rats With Adjuvant-induced Arthritis

Julio C Fernandes; Huijie Wang; Christian Jreyssaty; Mohamed Benderdour; Patrick Lavigne; Xingpin Qiu; Francoise M Winnik; Xiaoling Zhang; Kerong Dai; Qin Shi

doi:10.1038/mt.2008.99

Bone-protective Effects of Nonviral Gene Therapy With Folate–Chitosan DNA Nanoparticle Containing Interleukin-1 Receptor Antagonist Gene in Rats With Adjuvant-induced Arthritis

Molecular Therapy ◽

10.1038/mt.2008.99 ◽

2008 ◽

Vol 16 (7) ◽

pp. 1243-1251 ◽

Cited By ~ 50

Author(s):

Julio C Fernandes ◽

Huijie Wang ◽

Christian Jreyssaty ◽

Mohamed Benderdour ◽

Patrick Lavigne ◽

...

Keyword(s):

Gene Therapy ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Protective Effects ◽

Nonviral Gene Therapy ◽

Adjuvant Induced Arthritis ◽

Interleukin 1 Receptor Antagonist

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Editorial: Arthritis Gene Therapy Using Interleukin-1 Receptor Antagonist

Arthritis & Rheumatology ◽

10.1002/art.40675 ◽

2018 ◽

Vol 70 (11) ◽

pp. 1699-1701

Author(s):

Christopher Evans

Keyword(s):

Gene Therapy ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Interleukin 1 Receptor Antagonist

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In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy

Arthritis & Rheumatism ◽

10.1002/art.1780400604 ◽

1997 ◽

Vol 40 (6) ◽

pp. 1012-1019 ◽

Cited By ~ 246

Author(s):

Jean-Pierre Pelletier ◽

John P. Caron ◽

Christopher Evans ◽

Paul D. Robbins ◽

Helga I. Georgescu ◽

...

Keyword(s):

Gene Therapy ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Interleukin 1 Receptor Antagonist ◽

Experimental Osteoarthritis

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C3-Tat/HIV-regulated intraarticular human interleukin-1 receptor antagonist gene therapy results in efficient inhibition of collagen-induced arthritis superior to cytomegalovirus-regulated expression of the same transgene

Arthritis & Rheumatism ◽

10.1002/art.10481 ◽

2002 ◽

Vol 46 (6) ◽

pp. 1661-1670 ◽

Cited By ~ 21

Author(s):

A. C. Bakker ◽

F. A. J. van de Loo ◽

L. A. B. Joosten ◽

O. J. Arntz ◽

A. W. Varley ◽

...

Keyword(s):

Gene Therapy ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Collagen Induced Arthritis ◽

Interleukin 1 Receptor Antagonist ◽

Regulated Expression

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Gene therapy for rheumatoid arthritis: Lessons from animal models, including studies on interleukin-4, interleukin-10, and interleukin-1 receptor antagonist as potential disease modulators

Rheumatic Disease Clinics of North America ◽

10.1016/s0889-857x(03)00073-5 ◽

2002 ◽

Vol 28 (1) ◽

pp. 127-149 ◽

Cited By ~ 42

Author(s):

Fons A.J van de Loo ◽

Wim B van den Berg

Keyword(s):

Rheumatoid Arthritis ◽

Gene Therapy ◽

Animal Models ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Interleukin 10 ◽

Interleukin 4 ◽

Interleukin 1 Receptor Antagonist

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Gene therapy with the interleukin-1 receptor antagonist for the treatment of arthritis

Future Rheumatology ◽

10.2217/17460816.1.2.173 ◽

2006 ◽

Vol 1 (2) ◽

pp. 173-178 ◽

Cited By ~ 4

Author(s):

Christopher H Evans ◽

Steven C Ghivizzani ◽

Peter Wehling ◽

Paul D Robbins

Keyword(s):

Gene Therapy ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Interleukin 1 Receptor Antagonist

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Faculty Opinions recommendation of Gene Therapy for Osteoarthritis: Pharmacokinetics of Intra-Articular Self-Complementary Adeno-Associated Virus Interleukin-1 Receptor Antagonist Delivery in an Equine Model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.737756855.793573706 ◽

2020 ◽

Author(s):

Susanne Grässel

Keyword(s):

Gene Therapy ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Adeno Associated Virus ◽

Interleukin 1 Receptor Antagonist

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Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an in situ zymographic and gene therapy study

Arthritis Research & Therapy ◽

10.1186/ar2282 ◽

2007 ◽

Vol 9 (4) ◽

pp. R83 ◽

Cited By ~ 101

Author(s):

Christine L Le Maitre ◽

Judith A Hoyland ◽

Anthony J Freemont

Keyword(s):

Gene Therapy ◽

Intervertebral Disc ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Matrix Degradation ◽

Interleukin 1 Receptor Antagonist

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Interleukin-1 receptor antagonist gene therapy prevents and delays surgically-induced osteoarthritis in small and large animal models

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2018.02.122 ◽

2018 ◽

Vol 26 ◽

pp. S56-S57

Author(s):

M.W. Grol ◽

A. Nixon ◽

H.M. Lang ◽

M.Z. Ruan ◽

L. Begum ◽

...

Keyword(s):

Gene Therapy ◽

Animal Models ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Large Animal ◽

Interleukin 1 Receptor Antagonist ◽

Large Animal Models ◽

Surgically Induced

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Protection against collagen-induced arthritis by intramuscular gene therapy with an expression plasmid for the interleukin-1 receptor antagonist

Gene Therapy ◽

10.1038/sj.gt.3302042 ◽

2003 ◽

Vol 10 (18) ◽

pp. 1543-1550 ◽

Cited By ~ 33

Author(s):

J-M Kim ◽

J-G Jeong ◽

S-H Ho ◽

W Hahn ◽

E-J Park ◽

...

Keyword(s):

Gene Therapy ◽

Receptor Antagonist ◽

Interleukin 1 ◽

Collagen Induced Arthritis ◽

Expression Plasmid ◽

Interleukin 1 Receptor Antagonist

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1157. Suppression of Collagen-Induced Arthritis by Intramuscular Gene Therapy with Plasmid DNA Expressing the Interleukin-1 Receptor Antagonist

Molecular Therapy ◽

10.1016/s1525-0016(16)43987-0 ◽

2002 ◽

Vol 5 (5) ◽

pp. S376

Keyword(s):

Gene Therapy ◽

Receptor Antagonist ◽

Plasmid Dna ◽

Interleukin 1 ◽

Collagen Induced Arthritis ◽

Interleukin 1 Receptor Antagonist

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