scholarly journals Biological Pacemaker Engineered by Nonviral Gene Transfer in a Mouse Model of Complete Atrioventricular Block

2008 ◽  
Vol 16 (12) ◽  
pp. 1937-1943 ◽  
Author(s):  
Julien Piron ◽  
Khai Le Quang ◽  
François Briec ◽  
Jean-Christophe Amirault ◽  
Anne-Laure Leoni ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Mouse Model ◽  
Atrioventricular Block ◽  
Complete Atrioventricular Block ◽  
Nonviral Gene Transfer ◽  
Complete Atrioventricular ◽  
Biological Pacemaker

Adenoviral gene transfer of HCN4 creates a genetic pacemaker in pigs with complete atrioventricular block

Life Sciences ◽  
2007 ◽  
Vol 80 (19) ◽  
pp. 1746-1753 ◽  
Author(s):  
Jun Cai ◽  
Fang-Fang Yi ◽  
Yan-Hui Li ◽  
Xin-Chun Yang ◽  
Jian Song ◽  
...  
Keyword(s):  
Gene Transfer ◽  
Atrioventricular Block ◽  
Complete Atrioventricular Block ◽  
Adenoviral Gene Transfer ◽  
Complete Atrioventricular

Early ion-channel remodeling and arrhythmias precede hypertrophy in a mouse model of complete atrioventricular block

2011 ◽  
Vol 51 (5) ◽  
pp. 713-721 ◽  
Author(s):  
Olivier Bignolais ◽  
Khai Le Quang ◽  
Patrice Naud ◽  
Aziza El Harchi ◽  
François Briec ◽  
...  
Keyword(s):  
Mouse Model ◽  
Ion Channel ◽  
Atrioventricular Block ◽  
Complete Atrioventricular Block ◽  
Complete Atrioventricular

The Association Between Cardio-Ankle Vascular Index and Primary Idiopathic Complete Atrioventricular Block in an Elderly Population

Angiology ◽  
2021 ◽  
pp. 000331972110287
Author(s):  
Turhan Turan ◽  
Faruk Kara ◽  
Selim Kul ◽  
Muhammet Rasit Sayın ◽  
Sinan Sahin ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Atrioventricular Block ◽  
Elderly Population ◽  
Complete Atrioventricular Block ◽  
Age Related ◽  
And Gender ◽  
The Relationship ◽  
Block Frequency ◽  
Complete Atrioventricular ◽  
Relevant Factors

The most common cause of complete atrioventricular block (CAVB) is age-related fibrotic degeneration and is referred to as primary idiopathic complete atrioventricular block (iCAVB). This study aims to investigate the relationship between iCAVB and arterial stiffness using the cardio-ankle vascular index (CAVI). In this study, of 205 CAVB patients, 41 patients with iCAVB implanted with a dual-chamber permanent pacemaker and 40 age- and gender-matched controls were studied. Arterial stiffness was assessed by a VaSera VS-1000 CAVI instrument. The CAVI values of patients with iCAVB were significantly higher compared with the controls (9.63 ± 1.42 vs 8.57 ± 1.12, P < .001). Idiopathic complete atrioventricular block frequency was higher among patients with abnormal CAVI values than those with borderline and normal CAVI ( P = .04). In multivariate analysis, only CAVI was an independent predictor of iCAVB after adjusting for other relevant factors (odds ratio, 2.575; 95% CI [1.390-4.770]; P = .003). The present study demonstrated that CAVI, as a marker of arterial stiffness, was increased among elderly patients with iCAVB. Thus, we provide a possible additional mechanism linking easily measured CAVI with iCAVB.

scholarly journals Dopamine and epinephrine for managing complete atrioventricular block due to nonreperfused acute inferior wall myocardial infarction in a rural hospital: A case report

2021 ◽  
Vol 9 ◽  
pp. 2050313X2199611
Author(s):  
Evelyne Sandjojo ◽  
Vanessa AMC Jaury ◽  
Yufi K Astari ◽  
Mahendria Sukmana ◽  
Rizky A Haeruman ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Case Report ◽  
Atrioventricular Block ◽  
Pacemaker Implantation ◽  
Uncontrolled Hypertension ◽  
Definitive Treatment ◽  
Inferior Wall ◽  
Complete Atrioventricular Block ◽  
History Of ◽  
Complete Atrioventricular

Inferior wall myocardial infarction occurs in approximately 50% of all myocardial infarctions. The most common conduction disorder of this disease is complete atrioventricular block. Immediate attention must be given to the myocardial infarction patients with conduction block due to the increased mortality rate in these patients. Temporary pacemaker implantation and permanent pacemaker implantation are recommended in complete atrioventricular block cases that do not improve with reperfusion. In this case report, a 64-year-old-female patient came to the emergency department of a rural General Hospital with complaints of epigastric pain, dizziness, nausea, and vomiting for 2 days before admission. She had uncontrolled hypertension without a history of diabetes mellitus, dyslipidemia, smoking, or a family history of heart disease. The electrocardiogram displayed an acute inferior wall myocardial infarction and complete atrioventricular block with escape junctional rhythm with a heart rate of 17 bpm. She was diagnosed with nonreperfused inferior wall myocardial infarction and a complete atrioventricular block. She was successfully treated with only dopamine and epinephrine as the definitive treatment because the patient refused to be referred to a tertiary hospital for percutaneous coronary intervention and pacemaker implantation due to financial reasons. Dopamine and epinephrine may be considered for complete atrioventricular block if transfer to a higher level of care is not feasible and as bridge therapy while waiting for transfer.

Ebstein's Disease Associated with Complete Atrioventricular Block

CHEST Journal ◽  
1978 ◽  
Vol 73 (4) ◽  
pp. 542-544 ◽  
Author(s):  
James E. Price ◽  
Ezra A. Amsterdam ◽  
Zakauddin Vera ◽  
Robert Swenson ◽  
Dean T. Mason
Keyword(s):  
Atrioventricular Block ◽  
Complete Atrioventricular Block ◽  
Complete Atrioventricular
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