scholarly journals Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells

2016 ◽  
Vol 23 (3) ◽  
pp. 499-508 ◽  
Author(s):  
W Li ◽  
L Huang ◽  
J Zeng ◽  
W Lin ◽  
K Li ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Neural Crest Cells ◽  
Induced Pluripotent

scholarly journals Immunological Properties of Neural Crest Cells Derived from Human Induced Pluripotent Stem Cells

2019 ◽  
Vol 28 (1) ◽  
pp. 28-43 ◽  
Author(s):  
Shota Fujii ◽  
Satoru Yoshida ◽  
Emi Inagaki ◽  
Shin Hatou ◽  
Kazuo Tsubota ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Neural Crest Cells ◽  
Immunological Properties ◽  
Induced Pluripotent

scholarly journals Neural crest cells and their potential therapeutic applications

Morphologia ◽  
2021 ◽  
Vol 15 (3) ◽  
pp. 39-49
Author(s):  
K.M. Shevchenko
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Neural Crest ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Embryonic Stem ◽  
Neural Crest Cells ◽  
Red Bone Marrow ◽  
Induced Pluripotent ◽  
Promising Source

Neural crest (NC) is a population of cells, formed at the intersection between non-neural ectoderm and neural tube. Neural crest progenitors are multipotent, have capacity to extensive migration and self-renewal. They can be differentiated into various cells types from craniofacial skeletal tissues to components of peripheral nervous system. Influence of signaling molecules and transcription factors, which are expressed at the different stages regulate development of NC. The regulatory network of genes determines the processes of induction, specification, migration and differentiation of neural crest cells (NCC). The purpose of this article is to compare the characteristics of NCC, obtained from tissues of the embryo, fetus and adult; experimental strategies for obtaining NCC from embryonic stem cells, induced pluripotent stem cells, skin fibroblasts; comparison of the potential of different cell types for therapeutic use in a clinical setting. Embryonic stem NCC are differentiated to the trunk, cranial, cardiac, circumpharyngeal and vagal according to the area of their initial migration. Mature stem NCC can be obtained from the dorsal root ganglia, red bone marrow, hair follicle, skin, intestines, carotid body, heart, cornea, iris, dental pulp, hard palate and oral mucosa. Genetic mutations may lead to failure of regulation of NC development, which leads to many congenital human diseases such as cardiovascular defects, craniofacial abnormalities and intestinal aganglionosis, collectively known as neurocristopathies. The identification and isolation of multipotent stem NCC derived from adult tissues, embryonic stem cells, and induced pluripotent stem cells are promising source for regenerative medicine.

Generation of Neural Crest-Like Cells From Human Periodontal Ligament Cell-Derived Induced Pluripotent Stem Cells

2016 ◽  
Vol 232 (2) ◽  
pp. 402-416 ◽  
Author(s):  
Atsushi Tomokiyo ◽  
Kim Hynes ◽  
Jia Ng ◽  
Danijela Menicanin ◽  
Esther Camp ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Periodontal Ligament ◽  
Periodontal Ligament Cell ◽  
Induced Pluripotent

scholarly journals Neural crest stem cells can be induced in vitro from human-induced pluripotent stem cells using a novel protocol free of feeder cells

2021 ◽  
Vol 16 (3) ◽  
pp. 143-147
Author(s):  
Rei Abe ◽  
Kazuyo Yamauchi ◽  
Kazuki Kuniyoshi ◽  
Takane Suzuki ◽  
Yusuke Matsuura ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Feeder Cells ◽  
Neural Crest Stem Cells ◽  
Induced Pluripotent

scholarly journals Transplantation of Neural Crest-Like Cells Derived from Induced Pluripotent Stem Cells Improves Diabetic Polyneuropathy in Mice

2013 ◽  
Vol 22 (10) ◽  
pp. 1767-1783 ◽  
Author(s):  
Tetsuji Okawa ◽  
Hideki Kamiya ◽  
Tatsuhito Himeno ◽  
Jiro Kato ◽  
Yusuke Seino ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Crest ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Diabetic Polyneuropathy ◽  
Induced Pluripotent
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