scholarly journals Prognostic Significance of Fibrotic Focus in Invasive Ductal Carcinoma of the Breast: A Prospective Observational Study

2002 ◽  
Vol 15 (5) ◽  
pp. 502-516 ◽  
Author(s):  
Takahiro Hasebe ◽  
Satoshi Sasaki ◽  
Shigeru Imoto ◽  
Kiyoshi Mukai ◽  
Tomoyuki Yokose ◽  
...  
Keyword(s):  
Observational Study ◽  
Invasive Ductal Carcinoma ◽  
Prospective Observational Study ◽  
Ductal Carcinoma ◽  
Prognostic Significance ◽  
Carcinoma Of The Breast ◽  
Fibrotic Focus

The clinicopathological and prognostic significance of CD24, CD44, CD133, ALDH1 expressions in invasive ductal carcinoma of the breast

2015 ◽  
Vol 211 (10) ◽  
pp. 740-747 ◽  
Author(s):  
Nilgün Kapucuoğlu ◽  
Kemal Kürşat Bozkurt ◽  
Şirin Başpınar ◽  
Murat Koçer ◽  
Hasan Erol Eroğlu ◽  
...  
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Prognostic Significance ◽  
Carcinoma Of The Breast

Prognostic Significance of cyclin D1, β-catenin, and MTA1 in Patients with Invasive Ductal Carcinoma of the Breast

2012 ◽  
Vol 19 (13) ◽  
pp. 4129-4139 ◽  
Author(s):  
Chun-Wen Cheng ◽  
Yu-Fan Liu ◽  
Jyh-Cherng Yu ◽  
Hsiao-Wei Wang ◽  
Shian-Ling Ding ◽  
...  
Keyword(s):  
Cyclin D1 ◽  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Prognostic Significance ◽  
Carcinoma Of The Breast

scholarly journals Highly Proliferative Fibroblasts Forming Fibrotic Focus Govern Metastasis of Invasive Ductal Carcinoma of the Breast

2001 ◽  
Vol 14 (4) ◽  
pp. 325-337 ◽  
Author(s):  
Takahiro Hasebe ◽  
Satoshi Sasaki ◽  
Shigeru Imoto ◽  
Atsushi Ochiai
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Carcinoma Of The Breast ◽  
Fibrotic Focus

scholarly journals Prognostic significance of TMEM16A, PPFIA1, and FADD expression in invasive ductal carcinoma of the breast

2014 ◽  
Vol 12 (1) ◽  
pp. 137 ◽  
Author(s):  
Eun Choi ◽  
Jeong A Yun ◽  
Sahrish Jabeen ◽  
Eun Jeon ◽  
Hye Won ◽  
...  
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Prognostic Significance ◽  
Carcinoma Of The Breast

Prognostic significance of infiltrating immune cell subtypes in invasive ductal carcinoma of the breast

2018 ◽  
Vol 104 (3) ◽  
pp. 196-201 ◽  
Author(s):  
Yangmei Xu ◽  
Suzhen Lan ◽  
Qiuhong Zheng
Keyword(s):  
T Lymphocytes ◽  
Invasive Ductal Carcinoma ◽  
Immune Cell ◽  
Ductal Carcinoma ◽  
Prognostic Significance ◽  
Cancer Prognosis ◽  
Carcinoma Of The Breast ◽  
Invasive Ductal Breast Carcinoma ◽  
Kaplan Meier ◽  
Immune Cell Subsets

Purpose: To explore the correlation between tumor-infiltrating immune cell subsets and breast cancer prognosis. Materials and methods: Specimens of 102 patients with invasive ductal carcinoma of the breast were analyzed for immune-related markers (CD8, CD20, FOXP3 and CD68). The number of positive cells in the 3 most highly stained intratumoral stroma areas of the primary tumor was counted. The mean number was calculated and used to divide patients into 2 groups for each marker (CD8-high/CD8-low, CD20-high/CD20-low, FOXP3-high/FOXP3-low, and CD68-high/CD68-low). Results: Kaplan-Meier survival analysis showed (a) for all patients that high tumor-infiltrating CD8+ and CD20+ B lymphocytes, low tumor-infiltrating FOXP3+ regulatory T cells (Tregs), and CD68+ macrophages all increased OS and DFS (p<0.05); (b) for both the 35 ER-negative and 45 lymph–node-negative patients, high CD8+ cytotoxic T lymphocytes (CTLs) increased OS and DFS (p<0.05). Multivariate analysis of OS and DFS showed that for all patients high CD8+ CTLs and low FOXP3+ Tregs were related to good OS and DFS (p<0.05). Conclusion: High numbers of tumor-infiltrating CD8+ and low numbers of FOXP3+ T lymphocytes both could function as potential independent prognostic markers for invasive ductal breast carcinoma.

Multiphoton microscopic imaging of fibrotic focus in invasive ductal carcinoma of the breast

2014 ◽  
Author(s):  
Sijia Chen ◽  
Yuting Nie ◽  
Yuane Lian ◽  
Yan Wu ◽  
Fangmeng Fu ◽  
...  
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Carcinoma Of The Breast ◽  
Microscopic Imaging ◽  
Fibrotic Focus
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