Recommendations for the Reporting of Surgical Specimens Containing Uterine Cervical Neoplasms

The objectives of this study were to identify the associated factors with cancerous and precancerous lesions of cervix. In Africa, the incidence of uterine cervical neoplasms varies from one region to another, where most women with uterine cervical neoplasms are seen at an advanced stage. For this reason, uterine cervical neoplasms mass screening reduces the incidence and mortality due to this disease, similar to what is being done in Europe. A cross-sectional analytical study was conducted. Socio-demographic characteristics, gynaecological-obstetrical history, risk factors, data from visual inspection with acetic acid and visual inspection with Lugol, colposcopy impressions and results of cytological analysis were performed. A simple and multiple regression were performed to establish a statistically significant difference between certain factors and the presence of precancerous or cancerous lesions of uterine cervical. In this study, of 63 women diagnosed histologically, 43 had precancerous lesions and 20 had cancerous lesions. we found that being older than 35, having the first intercourse before 18, having an antecedent of STI, being a widow and using of tobacco were risk factors associated with precancerous lesions (p = 0.013 with OR = 3.44 (1.22–9.73), p = 0.009 with OR = 4.07 (1.69–13.08), p < 0.001 with OR = 3.80 (1.94–7.47), p < 0.001 with OR = 9.77 (3.87–24.70) and p < 0.001 with OR = 5.47 (2.60–11.52)) respectively. Only being older than 45, being a widow and using tobacco were risk factors associated with cancerous lesions (p = 0.021 with OR = 2.01 (1.58–3.56), p = 0.02 with OR = 2.96 (2.10–3.87), p = 0.041 with OR = 1.98 (1.46–2.44)) respectively. Among participants diagnosed with uterine cervical neoplasms, there was a significant association with the STI, marital status and smoking. Despite the integration of the detection of precancerous uterine cervical neoplasms lesions into health facilities in Gabon, uterine cervical neoplasms ranks second among women’s cancers in terms of incidence and first in terms of mortality.

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Sarcoma de Ewing extraóseo de origen ginecológico: tumor neuroectodérmico primitivo de localización infrecuente. Reporte de caso y revisión de la literatura

Revista Colombiana de Obstetricia y Ginecología ◽

10.18597/rcog.3023 ◽

2017 ◽

Vol 68 (2) ◽

pp. 135

Author(s):

Claudia Isabel Vivas-Flores ◽

Manuel Pantoja-Garrido ◽

Zoraida Frías-Sánchez

Keyword(s):

Uterine Cervical Neoplasms ◽

Cáncer De Mama ◽

Cervical Neoplasms ◽

Neuroectodermal Tumors ◽

Ewing Tumor ◽

Sarcoma De Ewing

Objetivo: presentar el caso de una paciente con diagnóstico de sarcoma de Ewing extraóseo cervicovaginal y realizar una revisión de la literatura, con especial atención al diagnóstico histopatológico y las posibilidades terapéuticas de estas neoplasias. Materiales y métodos: caso de una paciente de 53 años de edad, en seguimiento por antecedente de cáncer de mama ductal infiltrante, que presenta un sangrado genital anómalo. Tras la exploración física y los estudios con pruebas de imagen se observa una tumoración cervicovaginal que se extiende hacia la pelvis, de la cual se toma una biopsia. El resultado de la misma es compatible con sarcoma de Ewing / tumor neuroectodérmico primitivo cervical. Se realizó una búsqueda en las bases de datos Medline vía PubMed, con los términos: “sarcoma; ewing”, “neuroectodermal tumors”, “primitive”, “peripheral” y “uterine cervical neoplasms”, rastreando artículos de revisión bibliográfica, reportes y series de casos clínicos en inglés y español publicados desde 2009. Resultados: se hallaron doce artículos correspondientes a revisiones de literatura, reportes y series de casos clínicos, donde se describen los aspectos más importantes referentes al tratamiento, las manifestaciones clínicas y el diagnóstico molecular, inmunohistoquímico e histopatológico de esta patología.Conclusiones: el tumor de Ewing extraóseo ginecológico es una lesión extremadamente rara, cuyo diagnóstico se basa en el estudio de la morfología histopatológica, el examen inmunohistoquímico y las pruebas genéticas. La combinación de cirugía, quimioterapia y radioterapia se considera actualmente el tratamiento de elección.

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Human medicines European public assessment report (EPAR): Topotecan Hospira, topotecan, Uterine Cervical Neoplasms,Small Cell Lung Carcinoma, Date of authorisation: 09/06/2010, Revision: 14, Status: Authorised

Case Medical Research ◽

10.31525/cmr-5871d1 ◽

2019 ◽

Author(s):

Keyword(s):

Lung Carcinoma ◽

Small Cell Lung Carcinoma ◽

Small Cell ◽

Uterine Cervical Neoplasms ◽

Small Cell Lung ◽

Cervical Neoplasms ◽

Cell Lung Carcinoma ◽

Assessment Report ◽

European Public ◽

European Public Assessment Report

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