scholarly journals Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity

Leukemia ◽  
2011 ◽  
Vol 26 (5) ◽  
pp. 1127-1131 ◽  
Author(s):  
E Kostareli ◽  
M Gounari ◽  
A Janus ◽  
F Murray ◽  
X Brochet ◽  
...  
Keyword(s):  
B Cell ◽  
Rheumatoid Factor ◽  
Antigen Receptor ◽  
Factor Activity ◽  
Rheumatoid Factor Activity

scholarly journals Somatic Hypermutations Confer Rheumatoid Factor Activity in Hepatitis C Virus-Associated Mixed Cryoglobulinemia

2013 ◽  
Vol 65 (9) ◽  
pp. 2430-2440 ◽  
Author(s):  
Edgar D. Charles ◽  
Michael I. M. Orloff ◽  
Eiko Nishiuchi ◽  
Svetlana Marukian ◽  
Charles M. Rice ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Rheumatoid Factor ◽  
Mixed Cryoglobulinemia ◽  
Factor Activity ◽  
Rheumatoid Factor Activity

ANTI-e AND RHEUMATOID FACTOR ACTIVITY IN HEPATITIS B

The Lancet ◽  
1977 ◽  
Vol 309 (8019) ◽  
pp. 1008-1009 ◽  
Author(s):  
J.N. Kacaki ◽  
T.H. Siem ◽  
R. Brouwer
Keyword(s):  
Hepatitis B ◽  
Rheumatoid Factor ◽  
Factor Activity ◽  
Rheumatoid Factor Activity

Quantitation of Rheumatoid Factor Activity by Nephelometry

1979 ◽  
Vol 72 (3) ◽  
pp. 432-436 ◽  
Author(s):  
Clarence E. Jones ◽  
Robert J. Rousseau ◽  
Kameron W. Maxwell
Keyword(s):  
Rheumatoid Factor ◽  
Factor Activity ◽  
Rheumatoid Factor Activity

scholarly journals V gene usage by seven hybrids derived from CD5+ B-cell chronic lymphocytic leukemia and displaying autoantibody activity

Blood ◽  
1993 ◽  
Vol 82 (10) ◽  
pp. 3103-3112 ◽  
Author(s):  
O Pritsch ◽  
C Magnac ◽  
G Dumas ◽  
C Egile ◽  
G Dighiero
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Rheumatoid Factor ◽  
Variable Region ◽  
Lymphocytic Leukemia ◽  
Factor Activity ◽  
The Third ◽  
Gene Usage ◽  
Rheumatoid Factor Activity ◽  
V Gene ◽  
Available Information

Abstract We report here the complete heavy and light chain variable region sequences of seven heterohybridomas derived from CD5+ chronic lymphocytic leukemia (CLL) B lymphocytes and displaying natural autoantibody activity. The three hybrids displaying a polyreactive pattern of binding used VH4 family members, ie, the VH4–18 gene in germinal configuration in two cases and a VH4 gene with 90% homology with VH4–21 for the third one. A hybrid expressing anti-Sm activity used a VH3 family member with 95.26% homology with the 30P1 gene. The three hybrids exclusively displaying rheumatoid factor activity expressed VH1 family genes: 51P1 gene for two (in germinal configuration in one, and with 93.2% homology in the other), whereas the third one used the V1–3b gene (98.8% homology). Definitive homology with known germline D segments was found for four of the seven hybrids (DN2 in 3 and DLR4 in 1) and JH use appeared to be random. The three hybrids displaying polyreactive activity expressed V kappa I, V lambda III, and V lambda II genes, all in germinal configuration. Among the three hybrids with rheumatoid factor activity, two used the same V kappa II gene with, respectively, 98% and 96% homology with a gene previously described; the third used a V lambda I gene in germinal configuration. Finally, the clone with anti-Sm activity used a V lambda III gene having 97% homology with a germinal gene. Overall, these results attempt to establish the relationship between frequent self- reactivity observed in CD5+ B-CLL and V gene usage. For VH genes, they confirm overexpression of the 51P1 gene in B-CLL and suggest nonstochastic use of two VH4 genes (4–21 and 4–18). For VL genes, available information is too scarce to lead to firm conclusions.

Interference of rheumatoid factor activity by aspartame, a dipeptide methyl ester

1999 ◽  
Vol 12 (4) ◽  
pp. 249-257 ◽  
Author(s):  
Paul A. Ramsland ◽  
Bahereh F. Movafagh ◽  
Morris Reichlin ◽  
Allen B. Edmundson
Keyword(s):  
Methyl Ester ◽  
Rheumatoid Factor ◽  
Factor Activity ◽  
Rheumatoid Factor Activity

Hepatitis C Virus (HCV) Infection: Serum Rheumatoid Factor Activity and HCV Genotype Correlate With Cryoglobulin Clonality

Blood ◽  
1998 ◽  
Vol 92 (9) ◽  
pp. 3486-3488 ◽  
Author(s):  
Cristian Antonescu ◽  
Claude Mayerat ◽  
Alain Mantegani ◽  
Philippe C. Frei ◽  
François Spertini ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Rheumatoid Factor ◽  
Hcv Infection ◽  
Factor Activity ◽  
Hcv Genotype ◽  
Rheumatoid Factor Activity

ANTI-e AND RHEUMATOID FACTOR ACTIVITY IN HEPATITIS B

The Lancet ◽  
1977 ◽  
Vol 309 (8024) ◽  
pp. 1262-1263 ◽  
Author(s):  
RichardS Tedder ◽  
Moya Briggs
Keyword(s):  
Hepatitis B ◽  
Rheumatoid Factor ◽  
Factor Activity ◽  
Rheumatoid Factor Activity
Sign in / Sign up

Export Citation Format

Share Document