scholarly journals Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference

2014 ◽  
Vol 85 (3) ◽  
pp. 513-521 ◽  
Author(s):  
Patrick T. Murray ◽  
Ravindra L. Mehta ◽  
Andrew Shaw ◽  
Claudio Ronco ◽  
Zoltan Endre ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Consensus Conference ◽  
Acute Dialysis ◽  
Potential Use

scholarly journals RCPE UK Consensus Conference Statement: Management of acute kidney injury: the role

2013 ◽  
Vol 43 (1) ◽  
pp. 37-38 ◽  
Author(s):  
J Feehally ◽  
I Gilmore ◽  
S Barasi ◽  
M Bosomworth ◽  
B Christie ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Consensus Conference

Acute Dialysis Quality Initiative (ADQI): Methodology

2008 ◽  
Vol 31 (2) ◽  
pp. 90-93 ◽  
Author(s):  
J.A. Kellum ◽  
R. Bellomo ◽  
C. Ronco
Keyword(s):  
Acute Kidney Injury ◽  
Clinical Practice ◽  
Practice Guidelines ◽  
Expert Panel ◽  
Kidney Injury ◽  
Additional Research ◽  
Evidence Based ◽  
Acute Dialysis ◽  
Ongoing Process ◽  
Wide Acceptance

The Acute Dialysis Quality Initiative (ADQI) is an ongoing process that seeks to produce evidence-based recommendations for the prevention and management of acute kidney injury (AKI) and on different issues concerning acute dialysis. Our methods involve a combination of both expert panel and evidence appraisal, and this approach was chosen to achieve the best of both options. This approach has led to important practice guidelines with wide acceptance and adoption into clinical practice. We further recognize that additional research will be needed and have proposed specific studies that will help move this field forward.

scholarly journals Clinical Profile, Pharmacological Treatment, and Predictors of Death Among Hospitalized COVID-19 Patients With Acute Kidney Injury: A Population-Based Registry Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Eduardo Gutiérrez-Abejón ◽  
Débora Martín-García ◽  
Eduardo Tamayo ◽  
F. Javier Álvarez ◽  
Francisco Herrera-Gómez
Keyword(s):  
Acute Kidney Injury ◽  
Clinical Outcomes ◽  
Kidney Injury ◽  
Population Based ◽  
Hospital Death ◽  
Registry Study ◽  
Acute Dialysis ◽  
Population Based Registry ◽  
Very High ◽  
Registry Analysis

Introduction: One of the worst clinical outcomes of the coronavirus disease 2019 (COVID-19) pandemic was acute kidney injury (AKI).Methods: This manuscript presents results from a population-based registry study assessing treatment, comorbidities, and predictors of hospital death among COVID-19 patients with AKI from March 1st to May 31th, 2020. Death, oxygen delivery and ventilation, acute dialysis need, use of medications, and various clinical outcomes, in addition to the length of stay in the hospital and intensive care unit (ICU), were evaluated.Results: In Castile and Leon, the largest region of Spain, 10.87% of the patients admitted for COVID-19 (n = 7,307) developed AKI. These patients were known by having hypertension (57.93%), cardiovascular disease (48.99%), diabetes (26.7%) and chronic kidney disease (14.36%), and they used antibiotics (90.43%), antimalarials (60.45%), steroids (48.61%), antivirals (33.38%), anti-systemic inflammatory response syndrome (SIRS) drugs (9.45%), and tocilizumab (8.31%). Mortality among patients with AKI doubled that observed in patients without AKI (46.1 vs. 21.79%). Predictors of hospital death in COVID-19 patients with AKI were ventilation needs (OR = 5.9), treatment with steroids (OR = 1.7) or anti-SIRS (OR = 2.4), severe acute respiratory syndrome (SARS) occurrence (OR = 2.8), and SIRS occurrence (OR = 2.5).Conclusions: Acute kidney injury is a frequent and serious complication among COVID-19 patients, with a very high mortality, that requires more attention by treating physicians, when prescribing medications, by looking for manifestations particular to the disease, such as SARS or SIRS.

Myo-Inositol Oxygenase as a Predictor of Acute Kidney Injury in Critically ill Patients

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Hayem M Aref ◽  
Haitham Ezzat ◽  
Hussein S Hussein ◽  
Mona E Asaad
Keyword(s):  
Acute Kidney Injury ◽  
Early Diagnosis ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Kidney Injury ◽  
Control Group ◽  
Specific Enzyme ◽  
Diagnostic Sensitivity And Specificity ◽  
Time Of Admission ◽  
Potential Use

Abstract Background Acute kidney injury (AKI) affects 45% of critically ill patients, resulting in increased morbidity and mortality. The diagnostic standard, plasma creatinine, is nonspecific and may not increase until days after injury. Aim of the work to assess myo inositol oxygenase as noval marker in early detection of acute kidney injury critically ill patients. Patients and Methods In this prospective study, 40 critically ill patients were followed up in ICU up regarding development of Aki in ICU according to KDIGO definition. They were categorized into two subgroups; 20 patients developed AKI in and 20 patients who did not develop AKI. In addition, a control group of 20 individuals in Ain Shams Hospital during the period from 2018 to 2019, we did myoinositol oxygenase level test at time of admission and repeated in patients group which develop AKI within 24-48 hours. Results MIOX for the diagnosis of AKI When the cut-off value was taken as above 800, the diagnostic sensitivity and specificity of MIOX for AKI were 100%). For creatinine, at the cut-off value of above 0.9, the sensitivity for AKI were found 90% and specificity for AKI were found 65%. Conclusion The measurement of serum MIOX is valuable for the diagnosis of AKI. Further research is needed for the evaluation of the potential use of MIOX as a kidney-specific enzyme in the early diagnosis of AKI.

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