scholarly journals Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis

2011 ◽  
Vol 80 (4) ◽  
pp. 369-377 ◽  
Author(s):  
Yung-Hsiang Chen ◽  
Hsin-Ping Liu ◽  
Huey-Yi Chen ◽  
Fuu-Jen Tsai ◽  
Chiao-Hui Chang ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Heidi L. Erickson

Ethylene glycol, methanol, and diethylene glycol are readily available in many household and commercially available products. While these alcohols are relatively nontoxic themselves, their acidic metabolites are toxic and can result in significant morbidity and mortality. Herein we report a lethal case of massive ethylene glycol ingestion in a suicide with a record high level (1254 mg/dL) and images of the histologic examination of the kidneys revealing impressive calcium oxalate crystal deposition. Autopsy findings also showed evidence of mild cerebral edema.


Urology ◽  
2011 ◽  
Vol 77 (4) ◽  
pp. 1007.e9-1007.e14 ◽  
Author(s):  
Iwao Yoshioka ◽  
Masao Tsujihata ◽  
Wongswat Akanae ◽  
Norio Nonomura ◽  
Akihiko Okuyama

2014 ◽  
Vol 46 (6) ◽  
pp. 1231-1238 ◽  
Author(s):  
Mohammad Reza Naghii ◽  
Eslam Eskandari ◽  
Mahmood Mofid ◽  
Mehdi Jafari ◽  
Mohammad Hossein Asadi

2003 ◽  
Vol 127 (2) ◽  
pp. e89-e92
Author(s):  
Nathalie C. Rioux-Leclercq ◽  
Jonathan I. Epstein

Abstract We describe 2 cases of renal cell carcinoma arising in acquired cystic disease of the kidney (ACDK) in patients with end-stage renal disease undergoing hemodialysis for more than 5 years and provide a brief review of the complications of ACDK. In both cases, abundant calcium oxalate crystals were observed within the tumors. Histologically, one of the tumors was a conventional (clear cell) renal cell carcinoma. The other tumor was a bilateral papillary renal cell carcinoma. Both tumors were high-grade carcinomas with extensive oncocytic (acidophilic) features. Also noted within the kidneys were cysts with atypical papillary hyperplasia. The clinicopathologic findings along with review of the literature suggest a relationship between tumor growth and calcium oxalate crystal deposition in patients undergoing hemodialysis with ACDK.


2012 ◽  
Vol 23 (12) ◽  
pp. 2024-2033 ◽  
Author(s):  
Lauren M. Besenhofer ◽  
Marie C. Cain ◽  
Cody Dunning ◽  
Kenneth E. McMartin

2001 ◽  
Vol 149 (2) ◽  
pp. 209-218 ◽  
Author(s):  
Svoboda V. Pennisi ◽  
Dennis B. McConnell ◽  
Laurie B. Gower ◽  
Michael E. Kane ◽  
T. Lucansky

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