scholarly journals Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch–Schönlein purpura nephritis

2011 ◽  
Vol 80 (1) ◽  
pp. 79-87 ◽  
Author(s):  
Krzysztof Kiryluk ◽  
Zina Moldoveanu ◽  
John T. Sanders ◽  
T. Matthew Eison ◽  
Hitoshi Suzuki ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Henoch Schonlein Purpura ◽  
Aberrant Glycosylation ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
Purpura Nephritis

scholarly journals Renal Outcomes of Childhood IgA Nephropathy and Henoch Schönlein Purpura Nephritis

2021 ◽  
Vol 73 (10) ◽  
pp. 687-694
Author(s):  
Thanaporn Chaiyapak ◽  
Anirut Pattaragarn ◽  
Suroj Supavekin ◽  
Nuntawan Piyaphanee ◽  
Kraisoon Lomjansook ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Complete Recovery ◽  
Clinicopathological Characteristics ◽  
Henoch Schonlein Purpura ◽  
Renal Outcomes ◽  
Nephritic Syndrome ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
Purpura Nephritis

Background: Henoch-Schönlein purpura nephritis (HSPN) is considered the systemic form of IgA nephropathy (IgAN). However, differing clinicopathological features and renal outcomes of children with IgAN and HSPN have been reported in some studies. Methods: This study retrospectively reviewed children with IgAN and HSPN younger than 18 years, between January 2004 and December 2015. The clinicopathological characteristics at diagnosis and the renal outcomes after at least 1 year of follow-up were compared between the two groups. Results: A total of 54 children, comprising 21 with IgAN and 33 with HSPN, were recruited. The children with HSPN were younger than the children with IgAN. Gross hematuria and nephritic syndrome at the initial presentation were more common in children with IgAN. Regarding the pathological findings, IgAN had greater chronicity than HSPN. After a median follow-up period from first presentation to renal outcomes measurement of 4.0 years (1.3-12.2) in children with IgAN and 4.2 years (1.1-11.4) in children with HSPN, the renal outcomes were better in the latter group. The incidence of chronic kidney disease (CKD) was 28.6% in children with IgAN and 6.1% in children with HSPN (p = 0.02). Complete recovery was observed more frequently in children with HSPN than in children with IgAN (57.1% in IgAN vs. 87.9% in HSPN, p = 0.01). Conclusions: Childhood IgAN has greater chronicity and worse renal outcomes than childhood HSPN, with a lower rate of complete recovery and a higher frequency of CKD. We recommend long-term follow-up for CKD in children with IgAN.

scholarly journals Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis

BBA Clinical ◽  
2016 ◽  
Vol 5 ◽  
pp. 79-84 ◽  
Author(s):  
Rafael N. Moresco ◽  
Marijn M. Speeckaert ◽  
Slawomir C. Zmonarski ◽  
Magdalena Krajewska ◽  
Ewa Komuda-Leszek ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Transglutaminase 2 ◽  
Henoch Schonlein Purpura ◽  
New Biomarkers ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
Purpura Nephritis

scholarly journals A 10-YEAR-OLD GIRL WITH IGA NEPHROPATHY WHO 5 YEARS LATER DEVELOPED THE CHARACTERISTIC FEATURES OF HENOCH-SCHÖNLEIN PURPURA NEPHRITIS

2010 ◽  
Vol 56 (2) ◽  
pp. 157-161 ◽  
Author(s):  
MINA CHISHIKI ◽  
YUKIHIKO KAWASAKI ◽  
MARIKO KANEKO ◽  
YUMIKO USHIJIMA ◽  
SHINICHIRO OHARA ◽  
...  
Keyword(s):  
Iga Nephropathy ◽  
Henoch Schonlein Purpura ◽  
Characteristic Features ◽  
Schonlein Purpura ◽  
Henoch Schönlein Purpura ◽  
Purpura Nephritis
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