scholarly journals Tubular markers do not predict the decline in glomerular filtration rate in type 1 diabetic patients with overt nephropathy

2011 ◽  
Vol 79 (10) ◽  
pp. 1113-1118 ◽  
Author(s):  
Stine E. Nielsen ◽  
Steen Andersen ◽  
Dietmar Zdunek ◽  
Georg Hess ◽  
Hans-Henrik Parving ◽  
...  
2016 ◽  
Vol 60 (2) ◽  
pp. 108-116 ◽  
Author(s):  
Caroline Pereira Domingueti ◽  
Rodrigo Bastos Fóscolo ◽  
Ana Cristina Simões e Silva ◽  
Luci Maria S. Dusse ◽  
Janice Sepúlveda Reis ◽  
...  

2011 ◽  
Vol 96 (3) ◽  
pp. E485-E487 ◽  
Author(s):  
Charbel Abi Khalil ◽  
Kamel Mohammedi ◽  
Roberte Aubert ◽  
Elizabeth Abou Jaoude ◽  
Florence Travert ◽  
...  

Introduction: High total adiponectin (ADPN) levels were reported in type 1 diabetes (T1D) and related to long diabetes duration and nephropathy. We studied whether ADPN and its specific isoforms were elevated in T1D without microangiopathy and whether they were related to kidney function. Materials and Methods: Total, high, medium, and low molecular weight ADPN and insulin levels were measured in 47 consecutive normoalbuminuric, normotensive T1D patients without retinopathy and in 47 age-, sex-, and body mass index-matched controls. Glomerular filtration rate was estimated by 51Cr-EDTA plasma clearance. Results: Total and high molecular weight ADPN ratio were higher in T1D patients than in controls. ADPN levels were not related to anthropometric measures, whereas they were in controls. In T1D, ADPN levels were not related to glycosylated hemoglobin, diabetes duration, or glomerular filtration rate. Peripheral insulin levels were higher in T1D patients than in controls, but they were not related to ADPN levels. In controls, insulin levels were positively related to total ADPN. Conclusion: In T1D without microangiopathy, high ADPN levels could not be related to anthropometric diabetes parameters, kidney function, or high insulin levels. The nature of this elevation remains unknown.


Diabetologia ◽  
1984 ◽  
Vol 27 (6) ◽  
pp. 547-552 ◽  
Author(s):  
H. -H. Parving ◽  
H. Kastrup ◽  
U. M. Smidt ◽  
A. R. Andersen ◽  
B. Feldt-Rasmussen ◽  
...  

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1695-P
Author(s):  
STUART MCGURNAGHAN ◽  
ATHINA SPILIOPOULOU ◽  
HELEN M. COLHOUN ◽  
PAUL M. MCKEIGUE

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