Practical Algorithms in Pediatric Nephrology

INTRODUCTION. Among systemic vasopathies in children, IgA vasculitis Henoch Schoenlein (HS) is the most common, according to various authors, kidney damage is noted in 25-80 % and usually determines the prognosis of the disease.THE AIM of the study was to analyze clinical, laboratory, immunological, morphological characteristics, features of the course and treatment of nephritis associated with IgA vasculitis HS in children, as well as factors affecting the prognosis.PATIENTS AND METHODS. The study included 31 patients with morphologically verified nephritis due to IgA vasculitis HS (18 – boys, 13 – girls) aged 3 to 17 years, who were monitored at the Nephrology Department of the "2nd Children's City Clinical Hospital" of the National Center for Pediatric Nephrology and Renal Replacement therapy in Minsk from 2010 to 2019 yrs.The following parameters were analyzed: the clinical variant of kidney damage, laboratory tests (including the study of BAFF, RANTES lymphocyte activation molecules, pro-inflammatory IL1β, caspase1, TNFα, growth factors VEGF, TGF), 24 hours monitoring and office blood pressure measurements, ECHO cardiography with indicescalculation, ultrasound of the carotid arteries with the thickness of intima-media complex, morphological changes in the renal tissue, as well as treatment regimens.RESULTS. The contribution of deGal-IgA1, markers of T and B lymphocytes activation, pro-inflammatory and profibrotic molecules in the development of the disease is shown. Arterial hypertension was registered in 42 % of children, signs of heart remodeling according to the calculated indices in 19,3 %. Decrease level of adiponectin, vitamin D, leptin, increase concentration of obestatin, Pro-BNP, hs-CRP, and TSAT indicator classify patients with nephritis due to IgA vasculitis HS at moderate risk for the developmentof cardio-vascular disorders, which suggests the need for timely correction.CONCLUSION. In most cases, nephritis with IgA vasculitis HS has a benign course with rare relapses and progression to the end stage of chronic kidney disease (6,5 %).

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Expert consensus: practical algorithms for management of inflammatory bowel disease patients presenting with back pain or peripheral arthropathies

Alimentary Pharmacology & Therapeutics ◽

10.1111/apt.15519 ◽

2019 ◽

Vol 50 (11-12) ◽

pp. 1204-1213 ◽

Cited By ~ 4

Author(s):

Gaëlle Varkas ◽

Clio Ribbens ◽

Edouard Louis ◽

Filip Van den Bosch ◽

Rik Lories ◽

...

Keyword(s):

Inflammatory Bowel Disease ◽

Back Pain ◽

Bowel Disease ◽

Expert Consensus ◽

Practical Algorithms ◽

Inflammatory Bowel

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Abstracts of the XXVth Annual Meeting of the Japanese Society for Pediatric Nephrology, April 18?20, 1990, Chiba, Japan

Pediatric Nephrology ◽

10.1007/bf00856860 ◽

1992 ◽

Vol 6 (1) ◽

pp. C1-C14

Author(s):

Keyword(s):

Annual Meeting ◽

Japanese Society ◽

Pediatric Nephrology

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Telemedicine for Pediatric Nephrology: Perspectives on COVID-19, Future Practices, and Workflow Changes

Kidney Medicine ◽

10.1016/j.xkme.2021.01.007 ◽

2021 ◽

Author(s):

Rupesh Raina ◽

Nikhil Nair ◽

Aditya Sharma ◽

Ronith Chakraborty ◽

Sarah Rush

Keyword(s):

Pediatric Nephrology

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The individualized, accompanied transition program “TraiN” for adolescent kidney patients – a local initiative

Journal of Transition Medicine ◽

10.1515/jtm-2021-0002 ◽

2021 ◽

Vol 3 (1) ◽

Author(s):

Paula Collette ◽

Luisa C. Klein ◽

Lisa M. Körner ◽

Gundula Ernst ◽

Sandra Brengmann ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Disease Management ◽

Health Risks ◽

Pediatric Nephrology ◽

Young Patients ◽

Transition Program ◽

University Hospital ◽

Adult Care ◽

Local Initiative

Abstract Since the transition from pediatric and adolescent to adult care often proceeds unaccompanied and unplanned, young patients with chronic kidney disease may experience health risks and non-adherence after the transfer. The psychosocial team at the Department of Pediatric Nephrology at the University Hospital of Cologne has therefore developed its local transition program “TraiN” for patients with chronic kidney disease aged 13 years and older. It combines structure and flexibility through predefined content modules that can be individually adapted to the patients, offering continuity and sustainability through a transition contact person. In addition, the family members are offered regular psychological consultations. The timing of the transfer is chosen individually depending on the level of psychosocial and medical transition readiness. The aim of “TraiN” is to strengthen the patients’ transition competence and the responsibility for their disease management and to provide them and their families the best possible support during the transition in order to prevent possible health risks. In the near future, a scientific evaluation will be conducted aiming to determine whether “TraiN” can support young people in their independence and self-reliant disease management.

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