scholarly journals An IL-6 haplotype on human chromosome 7p21 confers risk for impaired renal function in type 2 diabetic patients

2008 ◽  
Vol 74 (4) ◽  
pp. 521-527 ◽  
Author(s):  
Daniel P.K. Ng ◽  
Siti Nurbaya ◽  
Sandra H.J. Ye ◽  
Andrzej S. Krolewski
Keyword(s):  
Renal Function ◽  
Human Chromosome ◽  
Impaired Renal Function ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

scholarly journals The relationships among hyperuricemia, body mass index and impaired renal function in type 2 diabetic patients

2018 ◽  
Vol 65 (3) ◽  
pp. 281-290 ◽  
Author(s):  
Yongmei Li ◽  
Xing Fan ◽  
Chunjun Li ◽  
Xinyue Zhi ◽  
Liyuan Peng ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Renal Function ◽  
Body Mass ◽  
Impaired Renal Function ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

scholarly journals The effect of HIV infection on glycaemia and renal function in type 2 diabetic patients

PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0199946 ◽  
Author(s):  
Siyabonga P. Khoza ◽  
Nigel J. Crowther ◽  
Sindeep Bhana
Keyword(s):  
Renal Function ◽  
Hiv Infection ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

scholarly journals Effects of sodium-glucose co-transporter 2 (SGLT2) inhibition on renal function and albuminuria in patients with type 2 diabetes: a systematic review and meta-analysis

PeerJ ◽  
2017 ◽  
Vol 5 ◽  
pp. e3405 ◽  
Author(s):  
Lubin Xu ◽  
Yang Li ◽  
Jiaxin Lang ◽  
Peng Xia ◽  
Xinyu Zhao ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Renal Function ◽  
Diabetic Patients ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Type 2 Diabetic Patients ◽  
Sglt2 Inhibition ◽  
Type 2 Diabetic

Aim To evaluate the effects of sodium-glucose co-transporter 2 (SGLT2) inhibition on renal function and albuminuria in patients with type 2 diabetes. Methods We conducted systematic searches of PubMed, Embase and Cochrane Central Register of Controlled Trials up to June 2016 and included randomized controlled trials of SGLT2 inhibitors in adult type 2 diabetic patients reporting estimated glomerular filtration rate (eGFR) and/or urine albumin/creatinine ratio (ACR) changes. Data were synthesized using the random-effects model. Results Forty-seven studies with 22,843 participants were included. SGLT2 inhibition was not associated with a significant change in eGFR in general (weighted mean difference (WMD), −0.33 ml/min per 1.73 m2, 95% CI [−0.90 to 0.23]) or in patients with chronic kidney disease (CKD) (WMD −0.78 ml/min per 1.73 m2, 95% CI [−2.52 to 0.97]). SGLT2 inhibition was associated with eGFR reduction in short-term trials (WMD −0.98 ml/min per 1.73 m2, 95% CI [−1.42 to −0.54]), and with eGFR preservation in long-term trials (WMD 2.01 ml/min per 1.73 m2, 95% CI [0.86 to 3.16]). Urine ACR reduction after SGLT2 inhibition was not statistically significant in type 2 diabetic patients in general (WMD −7.24 mg/g, 95% CI [−15.54 to 1.06]), but was significant in patients with CKD (WMD −107.35 mg/g, 95% CI [−192.53 to −22.18]). Conclusions SGLT2 inhibition was not associated with significant changes in eGFR in patients with type 2 diabetes, likely resulting from a mixture of an initial reduction of eGFR and long-term renal function preservation. SGLT2 inhibition was associated with statistically significant albuminuria reduction in type 2 diabetic patients with CKD.

Diabetic retinopathy and renal function in Chinese type 2 diabetic patients

2014 ◽  
Vol 46 (7) ◽  
pp. 1375-1381 ◽  
Author(s):  
Huiyan Zhang ◽  
Jianyong Wang ◽  
Gui-shuang Ying ◽  
Liping Shen ◽  
Zhe Zhang
Keyword(s):  
Renal Function ◽  
Diabetic Retinopathy ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

scholarly journals Analysis of serum inflammatory mediators in type 2 diabetic patients and their influence on renal function

PLoS ONE ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. e0229765 ◽  
Author(s):  
Liliane Silvano Araújo ◽  
Marcos Vinícius da Silva ◽  
Crislaine Aparecida da Silva ◽  
Maria de Fátima Borges ◽  
Heloísa Marcelina da Cunha Palhares ◽  
...  
Keyword(s):  
Renal Function ◽  
Inflammatory Mediators ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic
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