scholarly journals Countercurrent system

1990 ◽  
Vol 38 (4) ◽  
pp. 695-699 ◽  
Author(s):  
Jeff M. Sands ◽  
Juha P. Kokko
1987 ◽  
Vol 252 (6) ◽  
pp. F1095-F1102 ◽  
Author(s):  
P. Lory

Based on morphological observations, it has been concluded that the upper parts of the long descending limbs of Henle's loops should be able to secrete salts into the tubular fluid (Kriz, W. Federation Proc. 42:2379-2385, 1983). In the same article, a hypothesis is given depicting how this active transport in concert with certain characteristics of the medullary architecture might produce a transport cascade toward the papillary tip, thus supporting the accumulation of salts in this region. The effectiveness of the proposed mechanism can be judged by a mathematical model only. The computer simulations of the present study demonstrate that this mechanism indeed leads to an increase of the concentrating capability of the renal countercurrent system.


1984 ◽  
Vol 246 (2) ◽  
pp. F124-F132 ◽  
Author(s):  
M. F. Horster ◽  
A. Gilg ◽  
P. Lory

The renal medullary countercurrent system differentiates into its final segmental nephron function and geometry during perinatal development. The influence of these changes on the medullary longitudinal osmotic gradient cannot be evaluated by experimental studies. Therefore, a computation analysis using a differential equation model of the renal countercurrent system was applied to quantitate the effect of medullary architecture and solute transport on the concentration profiles for salt and urea in tubules (loop of Henle and collecting duct) and in the central core along the entire medulla during ontogeny. The results indicate that both the changing distribution of loop segments within the medulla and the increase in active salt transport of the individual thick ascending loop determine the magnitude and slope of the axial medullary solute gradients.


1964 ◽  
Vol 15 (5) ◽  
pp. 430-442 ◽  
Author(s):  
KNUT AUKLAND ◽  
ROBERT W. BERLINER

1972 ◽  
Vol 1 (3) ◽  
pp. 135-144 ◽  
Author(s):  
William M. Kettyle ◽  
Heinz Valtin

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