scholarly journals Influence of dialysate calcium concentration and vitamin D on serum parathyroid hormone during repetitive dialysis

1975 ◽  
Vol 7 (6) ◽  
pp. 422-432 ◽  
Author(s):  
Roger Bouillon ◽  
René Verberckmoes ◽  
Pieter De Moor
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Calcium Concentration ◽  
Serum Parathyroid Hormone ◽  
Dialysate Calcium

The Influence of Dialysate Calcium Concentration on the Pth Level in Children Undergoing Capd

1996 ◽  
Vol 16 (1_suppl) ◽  
pp. 567-569 ◽  
Author(s):  
Maria Sieniawska ◽  
Maria Roszkowska-Blaim ◽  
Beata Wojciechowska
Keyword(s):  
Mass Transfer ◽  
Peritoneal Dialysis ◽  
Parathyroid Hormone ◽  
Dwell Time ◽  
Calcium Concentration ◽  
Vitamin D Metabolites ◽  
Intact Parathyroid Hormone ◽  
Gland Function ◽  
Dialysate Calcium ◽  
Pth Level

In 12 children aged four-and-a-half to 18 years (mean 11 ±4.2) undergoing continuous ambulatory peritoneal dialysis (CAPO), serum intact parathyroid hormone (iPTH), ionized calcium (iCa) levels, and calcium mass transfer (CaMT) were measured on three consecutive days: day 1, after a four-hour interval between dialyses; on day 2, after four hours dwell time with peritoneal dialysis (PD) Ca 3.5 mEq/L; and on day 3, after four hours dwell time with PD Ca 2.5 mEq/L. A significantly more negative CaMT was found when PD Ca 2.5 mEq/L was used, as compared with values obtained using PD Ca 3.5 mEq/L. Significantly lower parathyroid hormone (PTH) values were found after the interval between exchanges. We conclude that in order to properly evaluate parathyroid gland function and to decide whether or not to give vitamin D metabolites, a protocol for determining PTH should be standardized.

Altered parathyroid set point to calcium in familial hypocalciuric hypercalcaemia

1984 ◽  
Vol 106 (2) ◽  
pp. 215-218 ◽  
Author(s):  
J. Auwerx ◽  
M. Demedts ◽  
R. Bouillon
Keyword(s):  
Parathyroid Hormone ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Linear Relationship ◽  
Calcium Concentration ◽  
Disodium Edta ◽  
Serum Parathyroid Hormone ◽  
Set Point ◽  
Serum Pth ◽  
The Right

Abstract. Changes in calcium concentration were induced by an infusion of disodium-EDTA or calcium in 2 members of a family suffering from hypocalciuric hypercalcaemia (FHH) associated with interstitial lung disease. These changes in calcium demonstrated an inverse linear relationship with the changes in serum parathyroid hormone (PTH). Infusion of EDTA in control subjects and in patients with an adenoma or hyperplasia of the parathyroid glands also showed inverse relationships between calcium and PTH. The correlation between serum calcium and serum PTH was significant over the range observed during the induced hypo- and/or hypercalcaemia in controls and in patients with FHH or adenoma. The regressions were, however, shifted relative to each other: in comparison with controls, the FHH was displaced upwards and to the right, although not as far as the adenomas. These findings suggest the existence of an elevated set point for extracellular calcium (or calciostat) in FHH.

Serum parathyroid hormone in hypophosphatemic vitamin D-resistant rickets

1972 ◽  
Vol 81 (2) ◽  
pp. 294-300 ◽  
Author(s):  
John E. Lewy ◽  
Emilio C. Cabana ◽  
Horacio A. Repetto ◽  
Janet M. Canterbury ◽  
Eric Reiss ◽  
...  
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
Serum Parathyroid Hormone ◽  
Vitamin D Resistant Rickets ◽  
Resistant Rickets

scholarly journals Parathyroid hormone in Sri Lankan pregnant women: Vitamin D and other determinants

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0258381
Author(s):  
Anusha Kaneshapillai ◽  
Usha Hettiaratchi ◽  
Shamini Prathapan ◽  
Guwani Liyanage
Keyword(s):  
Vitamin D ◽  
Regression Analysis ◽  
Parathyroid Hormone ◽  
Pregnant Women ◽  
Serum Calcium ◽  
Educational Level ◽  
Venous Blood ◽  
Sri Lankan ◽  
Serum Parathyroid Hormone ◽  
Cross Sectional

Introduction Determinants of parathyroid hormone level during pregnancy have been less frequently studied. We aimed to describe the serum parathyroid hormone (PTH) and its determinants in Sri Lankan pregnant women in a community setting. Materials and methods In this cross-sectional analysis, 390 pregnant mothers in their third trimester were enrolled from primary care centers of 15 health divisions in the Colombo District in Sri Lanka. Venous blood was analyzed for a total 25-hydroxyvitamin-D [25(OH)D], serum parathyroid hormone (PTH), serum calcium, and alkaline phosphatase. The bone quality was assessed in terms of speed of sound (SOS) using the quantitative ultrasound scan (QUS). Univariate and multivariate regression analysis was used to examine the determinants of PTH concentration in blood. Results Median serum 25(OH)D was 17.5ng/mL. Most (61.6%) were vitamin D deficient (<20ng/mL). Median PTH was 23.7pg/mL. Only 0.8% had hyperparathyroidism (PTH >65pg/mL). The correlation between 25(OH)D and PTH was weak but significant (r = -0.197; p<0.001). SOS Z-score was below the cut-off (≤−2) in fifty-six women (14.7%), and SOS did not relate significantly to PTH. In regression analysis, serum 25(OH)D, serum calcium, body mass index, educational level, and weeks of pregnancy were significant independent variables when adjusted. The model explained 16% of the variation in the PTH level. Conclusions A high prevalence of vitamin D deficiency was observed among Sri Lankan pregnant women in the present study. Serum 25(OH)D, calcium, weeks of pregnancy, and educational level were determinants of serum PTH.

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