scholarly journals Der p1 and Der p2-Specific T Cells Display a Th2, Th17, and Th2/Th17 Phenotype in Atopic Dermatitis

2015 ◽  
Vol 135 (9) ◽  
pp. 2324-2327 ◽  
Author(s):  
Lennart M. Roesner ◽  
Annice Heratizadeh ◽  
Gabriele Begemann ◽  
Petra Kienlin ◽  
Susanne Hradetzky ◽  
...  
Keyword(s):  
T Cells ◽  
Der P2 ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2578
Author(s):  
Masutaka Furue ◽  
Mihoko Furue

OX40 is one of the co-stimulatory molecules expressed on T cells, and it is engaged by OX40L, primarily expressed on professional antigen-presenting cells such as dendritic cells. The OX40L–OX40 axis is involved in the sustained activation and expansion of effector T and effector memory T cells, but it is not active in naïve and resting memory T cells. Ligation of OX40 by OX40L accelerates both T helper 1 (Th1) and T helper 2 (Th2) effector cell differentiation. Recent therapeutic success in clinical trials highlights the importance of the OX40L–OX40 axis as a promising target for the treatment of atopic dermatitis.


2021 ◽  
Vol 141 (5) ◽  
pp. S6
Author(s):  
G.C. Monnot ◽  
M. Wegrecki ◽  
B.N. Sallee ◽  
L.A. Bordone ◽  
C.H. Rohde ◽  
...  

2001 ◽  
Vol 107 (2) ◽  
pp. 359-366 ◽  
Author(s):  
Amy L. Woodward ◽  
Jonathan M. Spergel ◽  
Harri Alenius ◽  
Emiko Mizoguchi ◽  
Atul K. Bhan ◽  
...  

2008 ◽  
Vol 121 (2) ◽  
pp. S15-S15
Author(s):  
Y ITO ◽  
T MAKINO ◽  
Y ADACHI ◽  
H HIGASHIYAMA ◽  
T SHIMIZU ◽  
...  

2013 ◽  
Vol 133 (4) ◽  
pp. 973-979 ◽  
Author(s):  
DirkJan Hijnen ◽  
Edward F. Knol ◽  
Yoony Y. Gent ◽  
Barbara Giovannone ◽  
Scott J.P. Beijn ◽  
...  

2005 ◽  
Vol 153 (4) ◽  
pp. 750-757 ◽  
Author(s):  
M. Vukmanovic-Stejic ◽  
A. McQuaid ◽  
K.E. Birch ◽  
J.R. Reed ◽  
C. Macgregor ◽  
...  

2018 ◽  
Vol 46 (1) ◽  
pp. 37-42 ◽  
Author(s):  
Miki Kurita ◽  
Yuki Yoshihara ◽  
Yozo Ishiuji ◽  
Mami Chihara ◽  
Takaoki Ishiji ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  

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