scholarly journals Radical Scavenging Capacity in Human Skin before and after Vitamin C Uptake: An In Vivo Feasibility Study Using Electron Paramagnetic Resonance Spectroscopy

2013 ◽  
Vol 133 (4) ◽  
pp. 1102-1104 ◽  
Author(s):  
Anna-Christina Lauer ◽  
Norbert Groth ◽  
Stefan F. Haag ◽  
Maxim E. Darvin ◽  
Jürgen Lademann ◽  
...  
Keyword(s):  
Electron Paramagnetic Resonance ◽  
Electron Paramagnetic Resonance Spectroscopy ◽  
Radical Scavenging ◽  
Resonance Spectroscopy ◽  
Paramagnetic Resonance ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity ◽  
Before And After ◽  
Electron Paramagnetic

An Experimental Technique for Studying Chemisorption Reactions by Means of Electron Paramagnetic Resonance Spectroscopy

1972 ◽  
Vol 26 (2) ◽  
pp. 239-241 ◽  
Author(s):  
Eugene P. Scheide ◽  
George G. Guilbault
Keyword(s):  
Electron Paramagnetic Resonance ◽  
Experimental Method ◽  
Electron Paramagnetic Resonance Spectroscopy ◽  
Cupric Chloride ◽  
Resonance Spectroscopy ◽  
Epr Spectrum ◽  
Paramagnetic Resonance ◽  
Before And After ◽  
Chemisorption Bond ◽  
Electron Paramagnetic

A new experimental method and a specially designed EPR cell are described for use in the study of chemisorption reactions. By studying the EPR spectrum of a surface both before and after chemisorption, it can be shown whether unpaired d electrons are used in the chemisorption bond and the nature of this bond. The EPR spectra of a cupric chloride surface, both before and after a gaseous ligand (diisopropyl methyl phosphonate) is chemisorbed, are shown and the results are interpreted in terms of the type of bond formed.

The Measurement of Temperature With Electron Paramagnetic Resonance Spectroscopy

1996 ◽  
Vol 118 (2) ◽  
pp. 193-200 ◽  
Author(s):  
J. J. Eckburg ◽  
J. C. Chato ◽  
K. J. Liu ◽  
M. W. Grinstaff ◽  
H. M. Swartz ◽  
...  
Keyword(s):  
Electron Paramagnetic Resonance ◽  
Fatty Acid ◽  
Electron Paramagnetic Resonance Spectroscopy ◽  
In Vivo Studies ◽  
Acid Mixture ◽  
Resonance Spectroscopy ◽  
Temperature Sensitive ◽  
Paramagnetic Resonance ◽  
Electron Paramagnetic

An electron paramagnetic resonance (EPR) technique, potentially suitable for in vivo temperature measurements, has been developed based on the temperature response of nitroxide stable free radicals. The response has been substantially enhanced by encapsulating the nitroxide in a medium of a fatty acid mixture inside a proteinaceous microsphere. The mixture underwent a phase transition in the temperature range required by the application. The phase change dramatically altered the shape of the EPR spectrum, providing a highly temperature sensitive signal. Using the nitroxide dissolved in a cholesterol and a long-chain fatty acid ester, we developed a mixture which provides a peakheight ratio change from 3.32 to 2.11, with a standard deviation of 0.04, for a temperature change typical in biological and medical applications, from 38 to 48°C. This translated to an average temperature resolution of 0.2°C for our experimental system. The average diameter of the nitroxide mixture-filled microspheres was ≈2 μm. Therefore, they are compatible with in vivo studies where the microspheres could be injected into the microvasculature having a minimum vessel diameter of the order of 8 μm. This temperature measuring method has various potential clinical applications, especially in monitoring and optimizing the treatment of cancer with hyperthermia. However, several problems regarding temperature and spatial resolution need to be resolved before this technique can be successfully used to monitor temperatures in vivo.

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