scholarly journals ROS Quenching Potential of the Epidermal Cornified Cell Envelope

2011 ◽  
Vol 131 (7) ◽  
pp. 1435-1441 ◽  
Author(s):  
Wilbert P. Vermeij ◽  
A. Alia ◽  
Claude Backendorf
Keyword(s):  
Cell Envelope ◽  
Cornified Cell Envelope

Cornified cell envelope formation is distinct from apoptosis in epidermal keratinocytes

2000 ◽  
Vol 23 (3) ◽  
pp. 161-169 ◽  
Author(s):  
Hidetoshi Takahashi ◽  
Naoko Aoki ◽  
Satoshi Nakamura ◽  
Kazuhiro Asano ◽  
Akemi Ishida-Yamamoto ◽  
...  
Keyword(s):  
Cell Envelope ◽  
Epidermal Keratinocytes ◽  
Cornified Cell Envelope

102 Cornified cell envelope (CE) formation in Vohwinkel's syndrome (VS) is abnormal

1996 ◽  
Vol 12 (2) ◽  
pp. 198
Author(s):  
A. Ishida-Yamamoto ◽  
H. Iizuka ◽  
D. Hohl ◽  
D.R. Roop ◽  
J.A. McGrath ◽  
...  
Keyword(s):  
Cell Envelope ◽  
Cornified Cell Envelope

scholarly journals Periderm Cells Form Cornified Cell Envelope in Their Regression Process During Human Epidermal Development

1999 ◽  
Vol 112 (6) ◽  
pp. 903-909 ◽  
Author(s):  
Masashi Akiyama ◽  
Lynne T. Smith ◽  
Kozo Yoneda ◽  
Karen A. Holbrook ◽  
Daniel Hohl ◽  
...  
Keyword(s):  
Cell Envelope ◽  
Cornified Cell Envelope ◽  
Epidermal Development

scholarly journals Structural and Transglutaminase Substrate Properties of the Small Proline-rich 2 Family of Cornified Cell Envelope Proteins

1998 ◽  
Vol 273 (36) ◽  
pp. 23297-23303 ◽  
Author(s):  
Edit Tarcsa ◽  
Eleonora Candi ◽  
Tonja Kartasova ◽  
William W. Idler ◽  
Lyuben N. Marekov ◽  
...  
Keyword(s):  
Cell Envelope ◽  
Envelope Proteins ◽  
Substrate Properties ◽  
Cornified Cell Envelope

scholarly journals Biochemical, Structural, and Transglutaminase Substrate Properties Of Human Loricrin, the Major Epidermal Cornified Cell Envelope Protein

1995 ◽  
Vol 270 (44) ◽  
pp. 26382-26390 ◽  
Author(s):  
Eleonora Candi ◽  
Gerry Melino ◽  
Giampiero Mei ◽  
Edit Tarcsa ◽  
Soo-Il Chung ◽  
...  
Keyword(s):  
Envelope Protein ◽  
Cell Envelope ◽  
Substrate Properties ◽  
Cornified Cell Envelope

scholarly journals Evidence that filaggrin is a component of cornified cell envelopes in human plantar epidermis

1996 ◽  
Vol 317 (1) ◽  
pp. 173-177 ◽  
Author(s):  
Michel SIMON ◽  
Marek HAFTEK ◽  
Mireille SEBBAG ◽  
Martine MONTÉZIN ◽  
Elisabeth GIRBAL-NEUHAUSER ◽  
...  
Keyword(s):  
Stratum Corneum ◽  
Specific Binding ◽  
Cell Envelope ◽  
Epidermal Differentiation ◽  
Fibrous Matrix ◽  
Cornified Cell Envelope ◽  
Microscopy Analysis ◽  
Covalently Linked ◽  
Cell Envelopes ◽  
Plantar Stratum Corneum

Cornified cell envelope (CE) is generated during the late stages of epidermal differentiation and is made up of proteins covalently linked together by transglutaminases. To determine whether filaggrin is a component of this structure in humans, we analysed highly purified CE from plantar stratum corneum. An immunoelectron microscopy analysis showed specific binding of four different anti-(pro)filaggrin monoclonal antibodies to the surface of the CE, proved previously to be free of non-covalently linked proteins. Moreover, the anti-filaggrin activity of one of the antibodies was absorbed by preincubation with the plantar CE, as determined by ELISA. Convincingly, fragments of CE produced by proteolytic digestion of the structures were stained by this antibody on immunoblots. These data provide direct evidence that filaggrin is a component of CE purified from human plantar stratum corneum. Cross-linking between CE and the filaggrin-containing fibrous matrix may enhance the structural cohesion of the corneocytes and thus the resistance of the stratum corneum.

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