scholarly journals Comparison of Intradermal Test and Patch Test Using Nickel Sulfate and Formaldehyde

1963 ◽  
Vol 40 (5) ◽  
pp. 263-266 ◽  
Author(s):  
Poul V. Marcussen
2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Hai-yan Cheng ◽  
Lin-feng Li

Background. Xiaotong Tiegao (XTT) is an ancient topical Tibetan medicine plaster which is widely used in China. Irritant contact dermatitis (ICD) caused by XTT is very common. It is still unclear why some people are more prone to develop ICD. The aim of this study is to study the baseline skin biophysical parameters and patch test results in individuals predisposing to XTT induced ICD. Methods. During a four-month period, 149 healthy volunteers with ICD and 50 volunteers without ICD after applying XTT were recruited. The skin biophysical parameters were measured, and contact allergy to 20 common allergens was patch tested, at two weeks after the ICD was recovered. Results. There were no significant differences in age and sex between ICD and control groups. It was found that skin median melanin value (176.50 vs 189.50, P < 0.05, Mann-Whitney U-test) and erythema value (319.90 ± 70.49 vs 347.93 ± 84.55, P < 0.05, Independent-Samples T test) were much lower in ICD than control group. Overall patch test results were not different, but the positivity rate of nickel sulfate (15.44% vs 4.00%, P < 0.05, Fisher’s exact test) was significantly higher in ICD group. Conclusions. In conclusion, people with nickel allergy, lower values of skin melanin, and erythema are predisposing to develop ICD.


2019 ◽  
Vol 7 (2) ◽  
pp. 204-207 ◽  
Author(s):  
Phuong Pham Thi Minh ◽  
Trang Thi Minh ◽  
Doanh Le Huu ◽  
Thuong Nguyen Van ◽  
Sau Nguyen Huu ◽  
...  

BACKGROUND: Hand eczema is a common chronic and relapsing skin disease with various clinical features. Hand eczema aetiology can be allergic contact dermatitis (ACD), irritant contact dermatitis (ICD), atopic dermatitis (AD) and unknown or combination causes. If the causative agents are not detected treatment of hand eczema will be a failure. A patch test can be useful to detect causative agents in suspected allergic contact hand eczema. Then patients will avoid contacting them. This results in the improvement of hand eczema. In Vietnam, patch test has not been used before, so we conduct this study. AIM: To identify causative allergens by using patch test with 28 standard allergens in consecutive patients. METHODS: A group of 300 HE patients from the National Hospital of Dermatology and Venereology (NHDV) in Vietnam were enrolled in this study. They were divided into 4 groups-ACD, ICD, AD and unknown aetiology. The patient was patch tested with 28 standard allergens to identify the causative agents. RESULTS: Among the 300 HE enrolled patients, ACD accounted for 72.7%, AD and ICD had the same rate of 12.7%. 39.3% of the patients had a positive patch test. Reaction to nickel sulfate was the most common (10.3%), followed by potassium dichromate (9.7%), cobalt (4%) and fragrance mix (3.1%). About one-third of the cases had relevant clinical reactions correlated with the contact agents and clinical history. Males reacted to cement, thiuram mix and formaldehyde more than females, while females reacted to a nickel more than males. CONCLUSIONS: Hand eczema has variable clinical features and diverse aetiology. ACD is an important cause of hand eczema that can be managed with a patch test to detect causative allergens. Nearly 40% of HE cases had positive patch test. Relevant patch test reactions were seen in one-third of the patients. We propose using patch test detect causative agents in suspected allergic contact hand eczema. Then patients will avoid contacting them. This results in the improvement of hand eczema.


2007 ◽  
Vol 41 (2) ◽  
pp. 106-107 ◽  
Author(s):  
Javier Sánchez-Pérez ◽  
Beatriz Bartolomé ◽  
María Jesús Río ◽  
Amaro García-Díez

2004 ◽  
Vol 50 (4) ◽  
pp. 218-221 ◽  
Author(s):  
Gerd Molander ◽  
Leena Petman ◽  
Liisa Kannas ◽  
Antti I. Lauerma

Allergy ◽  
2007 ◽  
Vol 62 (12) ◽  
pp. 1462-1464 ◽  
Author(s):  
E. Macías ◽  
A. Ruiz ◽  
E. Moreno ◽  
E. Laffond ◽  
I. Dávila ◽  
...  
Keyword(s):  

2018 ◽  
Vol 79 (4) ◽  
pp. 250-251 ◽  
Author(s):  
Marta Tramontana ◽  
Katharina Hansel ◽  
Leonardo Bianchi ◽  
Daniela Agostinelli ◽  
Luca Stingeni

1996 ◽  
Vol 34 (2) ◽  
pp. 101-105 ◽  
Author(s):  
J. Handley ◽  
D. Todd ◽  
O. Dolan ◽  
D. McMaster ◽  
M. Walsh ◽  
...  

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