scholarly journals Autonomic and cardiovascular effects of pentobarbital anesthesia during trigeminal stimulation in cats

2012 ◽  
Vol 4 (1) ◽  
pp. 24-29 ◽  
Author(s):  
Hiroshi Hanamoto ◽  
Hitoshi Niwa ◽  
Mitsutaka Sugimura ◽  
Yoshinari Morimoto
Keyword(s):  
Cardiovascular Effects ◽  
Pentobarbital Anesthesia ◽  
Trigeminal Stimulation

Cardiovascular Effects of Anesthetic Doses of Pentobarbital Sodium

1956 ◽  
Vol 185 (1) ◽  
pp. 107-112 ◽  
Author(s):  
Clinton B. Nash ◽  
Floyd Davis ◽  
Robert A. Woodbury
Keyword(s):  
Cardiac Output ◽  
Cardiovascular System ◽  
Direct Action ◽  
Cardiovascular Effects ◽  
Experimental Period ◽  
Contour Method ◽  
Anesthetic Agent ◽  
Absolute Amount ◽  
Partial Recovery ◽  
Pentobarbital Anesthesia

The effects of continuous pentobarbital anesthesia on certain features of the cardiovascular system were investigated in trained male dogs. Similar results were obtained in 10 animals using the pressure-pulse contour method and in 5 animals by the dye dilution technique. Cardiac output fell progressively during the first 2–3 hours, the maximum fall exceeding 44% of control value, and was statistically significant from the 1-hour observation throughout the remainder of the 7-hour experimental period. Except for the brief period during induction, mean blood pressure did not deviate markedly from that of the unanesthetized animal. The fall in hematocrit during the 1st hour was followed by a slow partial recovery. Plasma proteins decreased both in concentration and absolute amount, while plasma volume showed a slight rise. The widely used anesthetic dose of 30 mg/kg seems needlessly high, and may be expected to induce cardiovascular changes even greater than those reported herein. This study has demonstrated clearly that a severe decrease in cardiac output occurs under continuous pentobarbital anesthesia in the dog. While the mechanism responsible for this fall has not been elucidated, it appears likely that a direct action on the myocardium may be involved. From the data presented it seems clear that published works which did not include specific control experiments for the effect of the anesthetic agent used require critical re-evaluation. This precaution is especially necessary in cardiovascular experiments involving pentobarbital anesthesia, since the data here reported indicate that this anesthetic agent itself produces marked changes in the cardiovascular system.

Ultrastructural Changes of Canine Kidneys During 24-Hour Perfusion on a LI-400 Preservation System

1971 ◽  
Vol 29 ◽  
pp. 316-317
Author(s):  
M. O. Magnusson ◽  
D. G. Osborne ◽  
T. Shimoji ◽  
W. S. Kiser ◽  
W. A. Hawk
Keyword(s):  
Electron Microscopy ◽  
Electrolyte Solution ◽  
Ultrastructural Changes ◽  
Midline Incision ◽  
Short Term ◽  
Pentobarbital Anesthesia ◽  
Pulsatile Perfusion

Short term experimental and clinical preservation of kidneys is presently best accomplished by hypothermic continuous pulsatile perfusion with cryoprecipitated and millipore filtered plasma. This study was undertaken to observe ultrastructural changes occurring during 24-hour preservation using the above mentioned method.A kidney was removed through a midline incision from healthy mongrel dogs under pentobarbital anesthesia. The kidneys were flushed immediately after removal with chilled electrolyte solution and placed on a LI-400 preservation system and perfused at 8-10°C. Serial kidney biopsies were obtained at 0-½-1-2-4-8-16 and 24 hours of preservation. All biopsies were prepared for electron microscopy. At the end of the preservation period the kidneys were autografted.

Cannabis-associated arteritis

VASA ◽  
2010 ◽  
Vol 39 (1) ◽  
pp. 43-53 ◽  
Author(s):  
Grotenhermen
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Case Series ◽  
Cardiovascular Effects ◽  
Causative Factor ◽  
Cannabis Use ◽  
Thromboangiitis Obliterans ◽  
Pathological Features ◽  
Scientific Support ◽  
Clinical And Pathological Features

Background: To investigate the hypothesis that cases of arteritis similar to thromboangiitis obliterans (TAO) and associated with the use of cannabis were caused by cannabis or THC (dronabinol), or that cannabis use is a co-factor of TAO. Patients and methods: A systematic review on case reports and the literature on so-called cannabis arteritis, TAO, and cardiovascular effects of cannabinoids was conducted. Results: Fifteen reports with 57 cases of an arteritis associated with the use of cannabis and two additional case series of TAO, in which some patients also used cannabis, were identified. Clinical and pathological features of cannabis-associated arteritis do not differ from TAO and the major risk factor of TAO, tobacco use, was present in most, if not in all of these cases. The proposed pathophysiological mechanisms for the development of an arteritis by cannabis use are not substantiated. Conclusions: The hypothesis of cannabis being a causative factor or co-factor of TAO or an arteritis similar to TAO is not supported by the available evidence. The use of the term “cannabis arteritis” should be avoided until or unless more convincing scientific support is forthcoming.

Some cardiovascular effects of the aqueous extract of the leaves of Starchytarpheta jamaicensis L. (Vahl)

Planta Medica ◽  
2006 ◽  
Vol 72 (11) ◽  
Author(s):  
M Idu ◽  
EKI Omogbai ◽  
F Amaechina ◽  
JE Ataman
Keyword(s):  
Aqueous Extract ◽  
Cardiovascular Effects

Cardiovascular effects of treatment with Liraglutide in a population with type 2 diabetes

2013 ◽  
Author(s):  
Marco Zavattaro ◽  
Flavia Prodam ◽  
Mauri Maria Grazia ◽  
Loredana Pagano ◽  
Marina Caputo ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Effects
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