scholarly journals Role of orexin-A in the ventrolateral preoptic area on components of total energy expenditure

2017 ◽  
Vol 41 (8) ◽  
pp. 1256-1262 ◽  
Author(s):  
J E Coborn ◽  
D P DePorter ◽  
V Mavanji ◽  
C M Sinton ◽  
C M Kotz ◽  
...  
Keyword(s):  
Energy Expenditure ◽  
Total Energy ◽  
Preoptic Area ◽  
Total Energy Expenditure ◽  
Orexin A ◽  
Ventrolateral Preoptic Area

scholarly journals O8A.5 Total energy expenditure and risk of lymphoma subtypes: results from the european epilymph case-control study

2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A71.2-A71
Author(s):  
Pierluigi Cocco
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Total Energy ◽  
Case Control Study ◽  
B Cell Lymphoma ◽  
Case Control ◽  
Total Energy Expenditure ◽  
Recreational Physical Activity ◽  
Control Study

IntroductionPhysical activity is known to convey protection against several cancers, but results on risk of lymphoma and its subtypes have been inconsistent. A possible reason might be confounding by workplace exposures associated with occupational energy expenditure, which was not considered in studies of recreational physical activity. It is also unclear whether energy expenditure acts directly, or through preventing obesity.ObjectivesTo investigate the role of energy expenditure, including occupational and recreational physical activity, on risk of lymphoma subtypes.Materials and methodsBased on questionnaire information on lifetime recreational physical activity and lifetime occupational history available for all participants to the multicenter EpiLymph case-control study, we estimated energy expenditure at work by occupational ISCO68 code, and we applied it to the work histories of study subjects. We also categorized hours of lifetime recreational physical activity into quartiles. We calculated risk of lymphoma subtypes with unconditional polytomous regression analysis, associated with increasing categories of lifetime energy expenditure at work (EEW), increasing categories of recreational physical activity (RPA), and their interaction term (total energy expenditure, TEE), adjusting by age, gender, education, body mass index (BMI), and history of farm work and solvents use.ResultsRisk of lymphoma overall, diffuse large B cell lymphoma and multiple myeloma was not associated with EEW, RPA and TEE. Risk of follicular lymphoma and chronic lymphocytic leukemia associated were elevated with medium and high EEW (OR 3.1, 95% CI 1.5–6.1; (OR 2.5 95% CI 1.2–5.1, respectively), but there was not a significant upward trend.ConclusionsFurther epidemiologic and mechanistic research is warranted to assess the role of physical activity in the etiology of lymphoma subtypes. New standardized energy expenditure assessment methods, as the ones herein developed, might contribute to a better understanding of the nature of the observed inconsistent findings.

scholarly journals Promotion of Wakefulness and Energy Expenditure by Orexin-A in the Ventrolateral Preoptic Area

SLEEP ◽  
2015 ◽  
Vol 38 (9) ◽  
pp. 1361-1370 ◽  
Author(s):  
Vijayakumar Mavanji ◽  
Claudio E. Perez-Leighton ◽  
Catherine M. Kotz ◽  
Charles J. Billington ◽  
Sairam Parthasarathy ◽  
...  
Keyword(s):  
Energy Expenditure ◽  
Preoptic Area ◽  
Orexin A ◽  
Ventrolateral Preoptic Area

scholarly journals The Role of Exercise Physical Activity in Varying the Total Energy Expenditure in Healthy Japanese Men 30 to 69 Years of Age

2003 ◽  
Vol 49 (2) ◽  
pp. 120-124 ◽  
Author(s):  
Hoby Hasina RAFAMANTANANTSOA ◽  
Naoyuki EBINE ◽  
Mayumi YOSHIOKA ◽  
Yutaka YOSHITAKE ◽  
Hiroaki TANAKA ◽  
...  
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Total Energy ◽  
Total Energy Expenditure ◽  
Japanese Men

scholarly journals β-Adrenergically Stimulated Fat Oxidation Is Diminished in Middle-Aged Compared to Young Subjects*

1999 ◽  
Vol 84 (10) ◽  
pp. 3764-3769
Author(s):  
E. E. Blaak ◽  
M. A. van Baak ◽  
W. H. M. Saris
Keyword(s):  
Skeletal Muscle ◽  
Energy Expenditure ◽  
Total Energy ◽  
Fat Oxidation ◽  
Substrate Utilization ◽  
Total Energy Expenditure ◽  
Adrenergic Stimulation ◽  
Middle Aged ◽  
Older Subjects ◽  
Young Subjects

Abstract The effect of aging on β-adrenergically mediated substrate utilization was investigated in nine young (25.2 ± 1.7 yr old) and eight older males (52.9 ± 2.1 yr old), matched for body weight and body composition. In a first experiment, the nonselectiveβ -agonist isoprenaline (ISO) was infused in increasing standardized doses, and during each infusion period energy expenditure and substrate utilization were determined by indirect calorimetry. In a second experiment, forearm skeletal muscle metabolism was studied during a standardized infusion dose of ISO (19 ng/kg fat-free mass·min). During β-adrenergic stimulation there was an increased carbohydrate oxidation (at an ISO infusion dose of 24 ng/kg fat-free mass·min, 31% vs. 21% of total energy expenditure; P < 0.05) and a decreased fat oxidation (51 vs. 62 of total energy expenditure; P < 0.05) in older compared to young subjects. Skeletal muscle lactate release significantly increased in the older subjects (from −175 ± 32 to −366 ± 66 nmol/100 mL forearm tissue·min), whereas there was no change in young subjects (from− 32 ± 21 to 23 ± 57 nmol/100 mL forearm tissue·min; interaction group × ISO, P < 0.01). Additionally, there was a tendency toward a blunted ISO-induced increase in nonesterified fatty acid uptake in the older subjects (interaction group × ISO, P = 0.062). Thus, middle-aged subjects have a blunted ability to oxidize fat during β-adrenergic stimulation compared to young subjects. This diminished fat oxidation may be an important etiological factor in the age-related increase in body fatness and obesity by favoring fat storage above oxidation.

Determination of total energy expenditure, resting metabolic rate and physical activity in lean and overweight people

1997 ◽  
Vol 36 (4) ◽  
pp. 310-312 ◽  
Author(s):  
F. Thielecke ◽  
J. Möseneder ◽  
A. Kroke ◽  
K. Klipstein-Grobusch ◽  
H. Boeing ◽  
...  
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Metabolic Rate ◽  
Total Energy ◽  
Resting Metabolic Rate ◽  
Total Energy Expenditure ◽  
Overweight People

scholarly journals Effect of smoking status on total energy expenditure

2010 ◽  
Vol 7 (1) ◽  
pp. 81 ◽  
Author(s):  
David P Bradley ◽  
Lindsey A Johnson ◽  
Zhumin Zhang ◽  
Amy F Subar ◽  
Richard P Troiano ◽  
...  
Keyword(s):  
Energy Expenditure ◽  
Total Energy ◽  
Smoking Status ◽  
Total Energy Expenditure

Total Energy Expenditure and Physical Activity Measured with the Bicarbonate-Urea Method in Patients with Human Immunodeficiency Virus Infection

1996 ◽  
Vol 91 (2) ◽  
pp. 241-245 ◽  
Author(s):  
N. I. J. Paton ◽  
M. Elia ◽  
S. A. Jebb ◽  
G. Jennings ◽  
D. C. MacAllan ◽  
...  
Keyword(s):  
Physical Activity ◽  
Energy Expenditure ◽  
Total Energy ◽  
Physical Activity Level ◽  
Resting Energy Expenditure ◽  
Total Energy Expenditure ◽  
Activity Level ◽  
Hiv Positive ◽  
Urea Method ◽  
Resting Energy

1. Our objectives were to measure total energy expenditure, the daily variation in total energy expenditure and the physical activity level in a group of HIV-positive subjects using the bicarbonate-urea method. The study also aimed to assess the practicalities of using the bicarbonate-urea technique in free-living conditions. 2. Total energy expenditure was measured with the bicarbonate-urea method over 2 consecutive days (1 day in one subject) in 10 male patients with HIV infection (median CD4 count = 30). Resting energy expenditure was measured by indirect calorimetry. Physical activity level (total energy expenditure/resting energy expenditure) was calculated from these measurements and from activity diaries. 3. Resting energy expenditure was found to be 7.46 ± 0.87 MJ/day, 5% higher than predicted values. Total energy expenditure was 10.69 ± 1.95 MJ/day with an intra-individual day-to-day variation of 6 ± 6%. The measured physical activity level was 1.42 ± 0.14, higher than the diary estimate of 1.34 ± 0.16 (P = 0.029), and there were large inter-method differences in individual values. The subcutaneous infusion of bicarbonate was well tolerated and did not seem to restrict normal activities. 4. Total energy expenditure was not elevated in the group of HIV-positive subjects when compared with reference values for normal subjects. The physical activity level of the patients in this study was lower than that measured using other techniques in healthy young men, but was compatible with that expected for people leading a sedentary lifestyle. Reductions in physical activity in patients with HIV are likely to contribute to the wasting process and physical activity level may thus be a clinically useful measure. This study has also provided the first tracer estimate of the day-to-day variation in total energy expenditure. The bicarbonate-urea method represents an important new investigative tool for measuring total energy expenditure which has previously only been possible within the confines of a whole-body calorimeter or using the expensive doubly labelled water method.

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