Nesfatin-1 exerts long-term effect on food intake and body temperature

2012 ◽  
Vol 36 (12) ◽  
pp. 1514-1521 ◽  
Author(s):  
K Könczöl ◽  
O Pintér ◽  
S Ferenczi ◽  
J Varga ◽  
K Kovács ◽  
...  
1996 ◽  
Vol 1996 ◽  
pp. 174-174
Author(s):  
A.M. Sibbald

Voluntary food intake is generally inversely related to body condition or fatness in mature sheep (Foot, 1972). Since the intake of pelleted diets by housed sheep consists of a number of discrete feeding bouts or 'meals' (e.g. Bermudez et al., 1989), the relatively long-term effect of body condition on intake will be achieved through changes in feeding behaviour at the level of a single meal. The aim of this experiment was to compare the effects of body condition and short-term food restriction on meal patterns in sheep, to investigate the mechanism by which body condition influences daily food intake.


1973 ◽  
Vol 5 (03) ◽  
pp. 223-224 ◽  
Author(s):  
D. Lemonnier ◽  
J-P. Suquet ◽  
R. Aubert ◽  
G. Rosselin

2006 ◽  
Vol 82 (5) ◽  
pp. 751-762 ◽  
Author(s):  
F. Quevedo ◽  
C. Cervera ◽  
E. Blas ◽  
M. Baselga ◽  
J. J. Pascual

AbstractA total of 166 crossbred does were used to study the possible long-term effect of two types of crossbred does (H1v.H2, old and current generations, respectively) from the cross of different generations of lines selected for litter size, the use of a rearing programme based on a low-energy diet, and the administration of a high-energy diet during reproductive life, on the performance and body condition of lactating rabbit does and their litters until slaughter. The body condition of the reproductive rabbit does increased in the successive cycles to the fourth parturition, being maintained from this moment on. Animals more selected for litter size at weaning presented a greater food intake (+3%;P<0·05) and milk yield (+6%;P<0·05) during the first 21 days of lactation, which could be related to greater maternal aptitude. The difference in the weight of pups at slaughter time (+24 g for H2 respect to H1 pups) was one third lower than that expected from the generation response of the paternal line (0·45 g/day), perhaps related to the different enteropathy incidence depending on the genetic type. The use of a high-energy diet during the reproduction period increased the milk yield (+22%;P<0·05) of does, as the growth (+16 g at weaning day;P<0·05) and survival index (+2%;P<0·05) of the litters during lactation, but could produce a more sudden weaning of pups as a consequence of their lower pre-weaning food intake (−42%;P<0·05), which has been related with a greater health risk index during the growing period (+4·2%;P<0·05). Reproductive does given a high fibre diet during the rearing period (from 3 kg live weight to 28th day of the first pregnancy) reached parturition with a higher live weight than does that received a moderate energy diet restricted during this same period (+142 g;P<0·05). All other parameters controlled for the lactating does and their litters were not affected by the type of diet received during the rearing period. Females that were not effectively mated at first AI (11 dayspost partum) showed a greater increase in their perirenal fat thickness between partum and the 11th day of lactation than those lactating females that showed an effective mating (+0·22v.+0·37 mm, respectively;P<0·05).


2017 ◽  
Vol 242 (15) ◽  
pp. 1499-1507 ◽  
Author(s):  
Elizabeth A Davis ◽  
Martha C Washington ◽  
Emily R Yaniz ◽  
Heidi Phillips ◽  
Ayman I Sayegh ◽  
...  

Intestinal epithelial tissue is constantly regenerated as a means to maintain proper tissue function. Previous studies have demonstrated that denervation of the parasympathetic or sympathetic nervous system to the intestine alters this process. However, results are inconsistent between studies, showing both increases and decreases in proliferation after denervation of the parasympathetic or sympathetic. The effect appears to correlate with (1) the timing post-denervation, (2) denervation-induced changes in food intake, (3) the denervation technique used, and (4) which intestinal segment is investigated. Thus, we proposed that parasympathetic or sympathetic denervation does not have an effect on intestinal epithelial regeneration when you (1) evaluate denervation after long-term denervation, (2) control for post-surgical changes in food intake, (3) use minimally invasive surgical techniques and (4) include a segmental analysis. To test this, adult male Sprague Dawley rats underwent parasympathetic denervation via subdiaphragmatic vagotomy, sympathetic denervation via celiacomesenteric ganglionectomy, a parasympathetic denervation sham surgery, or a sympathetic denervation sham surgery. Sham surgery ad libitum-fed groups and sham surgery pair-fed groups were used to control for surgically induced changes in food intake. Three weeks post-surgery, animals were sacrificed and tissue from the duodenum, jejunum, and ileum was excised and immunohistochemically processed to visualize indicators of proliferation (bromodeoxyuridine-positive cells) and apoptosis (caspase-3-positive cells). Results showed no differences between groups in proliferation, apoptosis, or total cell number in any intestinal segment. These results suggest that parasympathetic or sympathetic denervation does not have a significant long-term effect on intestinal epithelial turnover. Thus, intestinal epithelial regeneration is able to recover after autonomic nervous system injury. Impact statement This study investigates the long-term effect of autonomic denervation on intestinal epithelial cell turnover, as measured by proliferation, apoptosis, and total cell number. Although previous research has established that autonomic denervation can alter intestinal epithelial turnover under short-term conditions, here we establish for the first time that these changes do not persist long-term when you control for surgical-induced changes in food intake and use targeted denervation procedures. These findings add to the base of knowledge on autonomic control of tissue turnover, highlight the ability of the intestinal epithelium to recover after autonomic injury and reveal possible implications of the use of ANS denervation for disease treatment in humans.


2002 ◽  
Vol 2002 ◽  
pp. 47-47
Author(s):  
M. Marie ◽  
P.A. Findlay ◽  
L. Thomas ◽  
C.L. Adam

Circulating leptin, the obese gene product secreted by adipocytes, is sensitive to short-term (meals, starvation) and long-term (spontaneous food intake, food restriction) changes in energy balance in sheep (Marie et al 2001). The present study aimed to explore relationships between adiposity, adipose tissue from different sites and blood leptin concentrations in rams kept in long days when adiposity is normally high.


1996 ◽  
Vol 1996 ◽  
pp. 174-174
Author(s):  
A.M. Sibbald

Voluntary food intake is generally inversely related to body condition or fatness in mature sheep (Foot, 1972). Since the intake of pelleted diets by housed sheep consists of a number of discrete feeding bouts or 'meals' (e.g. Bermudez et al., 1989), the relatively long-term effect of body condition on intake will be achieved through changes in feeding behaviour at the level of a single meal. The aim of this experiment was to compare the effects of body condition and short-term food restriction on meal patterns in sheep, to investigate the mechanism by which body condition influences daily food intake.


2010 ◽  
Vol 213 (2-3) ◽  
pp. 365-376 ◽  
Author(s):  
Ratchanee Rodsiri ◽  
Clare Spicer ◽  
A. Richard Green ◽  
Charles A. Marsden ◽  
Kevin C. F. Fone

2010 ◽  
Author(s):  
Andreas T. Breuer ◽  
Michael E. J. Masson ◽  
Glen E. Bodner
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document