UCP1 genetic polymorphism (–3826 A/G) diminishes resting energy expenditure and thermoregulatory sympathetic nervous system activity in young females

2010 ◽  
Vol 35 (8) ◽  
pp. 1050-1055 ◽  
Author(s):  
N Nagai ◽  
N Sakane ◽  
K Tsuzaki ◽  
T Moritani
Keyword(s):  
Nervous System ◽  
Genetic Polymorphism ◽  
Energy Expenditure ◽  
Sympathetic Nervous System ◽  
Resting Energy Expenditure ◽  
Sympathetic Nervous System Activity ◽  
System Activity ◽  
Young Females ◽  
Nervous System Activity ◽  
Sympathetic Nervous

scholarly journals Urinary Norepinephrine Is a Metabolic Determinant of 24-Hour Energy Expenditure and Sleeping Metabolic Rate in Adult Humans

2020 ◽  
Vol 105 (4) ◽  
pp. 1145-1156 ◽  
Author(s):  
Tim Hollstein ◽  
Alessio Basolo ◽  
Takafumi Ando ◽  
Susanne B Votruba ◽  
Jonathan Krakoff ◽  
...  
Keyword(s):  
Physical Activity ◽  
Nervous System ◽  
Energy Balance ◽  
Energy Expenditure ◽  
Sympathetic Nervous System ◽  
Metabolic Rate ◽  
Sympathetic Nervous System Activity ◽  
System Activity ◽  
Nervous System Activity ◽  
Sympathetic Nervous

Abstract Background Interindividual variability in 24-hour energy expenditure (24EE) during energy-balance conditions is mainly determined by differences in body composition and demographic factors. Previous studies suggested that 24EE might also be influenced by sympathetic nervous system activity via catecholamine (norepinephrine, epinephrine) secretion. Therefore, we analyzed the association between catecholamines and energy expenditure in 202 individuals from a heterogeneous population of mixed ethnicities. Methods Participants (n = 202, 33% female, 14% black, 32% white, 41% Native American, 11% Hispanic, age: 36.9 ± 10.3 y [mean ± SD], percentage body fat: 30.3 ± 9.4) resided in a whole-room calorimeter over 24 hours during carefully controlled energy-balance conditions to measure 24EE and its components: sleeping metabolic rate (SMR), awake-fed thermogenesis (AFT), and spontaneous physical activity (SPA). Urine samples were collected, and 24-h urinary epinephrine and norepinephrine excretion rates were assessed by high-performance liquid chromatography. Results Both catecholamines were associated with 24EE and SMR (norepinephrine: +27 and +19 kcal/d per 10 μg/24h; epinephrine: +18 and +10 kcal/d per 1 μg/24h) in separate analyses after adjustment for age, sex, ethnicity, fat mass, fat-free mass, calorimeter room, temperature, and physical activity. In a multivariate model including both norepinephrine and epinephrine, only norepinephrine was independently associated with both 24EE and SMR (both P < .008), whereas epinephrine became insignificant. Neither epinephrine nor norepinephrine were associated with adjusted AFT (both P = .37) but epinephrine was associated with adjusted SPA (+0.5% per 1 μg/24h). Conclusions Our data provide compelling evidence that sympathetic nervous system activity, mediated via norepinephrine, is a determinant of human energy expenditure during nonstressed, eucaloric conditions.

scholarly journals Sympathetic support of energy expenditure and sympathetic nervous system activity after gastric bypass surgery

Obesity ◽  
2013 ◽  
Vol 21 (3) ◽  
pp. 480-485 ◽  
Author(s):  
Timothy B. Curry ◽  
Madhuri Somaraju ◽  
Casey N. Hines ◽  
Cornelius B. Groenewald ◽  
John M. Miles ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Nervous System ◽  
Energy Expenditure ◽  
Sympathetic Nervous System ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Sympathetic Nervous System Activity ◽  
System Activity ◽  
Nervous System Activity ◽  
Sympathetic Nervous

scholarly journals Magnesium Dynamics and Sympathetic Nervous System Activity in Patients With Chronic Heart Failure

1999 ◽  
Vol 63 (4) ◽  
pp. 267-273 ◽  
Author(s):  
Hisanori Samejima ◽  
Kazuhiko Tanabe ◽  
Noriyuki Suzuki ◽  
Kazuto Omiya ◽  
Masahiro Murayama
Keyword(s):  
Heart Failure ◽  
Nervous System ◽  
Chronic Heart Failure ◽  
Sympathetic Nervous System ◽  
Sympathetic Nervous System Activity ◽  
System Activity ◽  
Nervous System Activity ◽  
Sympathetic Nervous

scholarly journals Sympathetic nervous system activity after gastric bypass surgery

2011 ◽  
Vol 25 (S1) ◽  
Author(s):  
Madhuri Somaraju ◽  
Jessica Sawyer ◽  
John Miles ◽  
Michael Joyner ◽  
Nisha Charkoudian ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Nervous System ◽  
Sympathetic Nervous System ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Sympathetic Nervous System Activity ◽  
System Activity ◽  
Nervous System Activity ◽  
Sympathetic Nervous
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