scholarly journals The increase of fatty acid-binding protein aP2 in overweight and obese children: interactions with dietary fat and impact on measures of subclinical inflammation

2008 ◽  
Vol 32 (10) ◽  
pp. 1513-1520 ◽  
Author(s):  
I Aeberli ◽  
N Beljean ◽  
R Lehmann ◽  
D l'Allemand ◽  
G A Spinas ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Dietary Fat ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Subclinical Inflammation ◽  
Obese Children ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

The intestinal fatty acid binding protein is not essential for dietary fat absorption in mice

2000 ◽  
Vol 14 (13) ◽  
pp. 2040-2046 ◽  
Author(s):  
Galya Vassileva ◽  
Leslie Huwyler ◽  
Kevin Poirier ◽  
Luis B. Agellon ◽  
Matthew J. Toth
Keyword(s):  
Fatty Acid ◽  
Dietary Fat ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fat Absorption ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Dietary Fat Absorption

Adipocyte fatty acid–binding protein in obese children before and after weight loss

Metabolism ◽  
2007 ◽  
Vol 56 (12) ◽  
pp. 1735-1741 ◽  
Author(s):  
Thomas Reinehr ◽  
Birgit Stoffel-Wagner ◽  
Christian L. Roth
Keyword(s):  
Weight Loss ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Obese Children ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Before And After

scholarly journals Weight loss in prepubertal obese children is associated with a decrease in adipocyte fatty-acid-binding protein without changes in lipocalin-2: a 2-year longitudinal study

2010 ◽  
Vol 163 (6) ◽  
pp. 887-893 ◽  
Author(s):  
Raquel Corripio ◽  
José-Miguel Gónzalez-Clemente ◽  
Jacobo Pérez-Sánchez ◽  
Sílvia Näf ◽  
Lluís Gallart ◽  
...  
Keyword(s):  
Weight Loss ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Resistance Index ◽  
Oral Glucose ◽  
Lipocalin 2 ◽  
Obese Children ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

ContextLipocalin-2 and adipocyte fatty-acid-binding protein (A-FABP or FABP4) are adipokines potentially involved in the pathophysiology of obesity and metabolic syndrome in adults. In children, they have been scarcely studied.ObjectiveTo analyze lipocalin-2 and A-FABP circulating levels before and after 2 years of a dieting and lifestyle intervention in a prepubertal obese cohort.Design and settingCase–control study with a prospective follow-up of cases for 2 years in our referral pediatric endocrine outpatient center.Patients and methodsSeventy-three prepubertal obese children, 8.03±1.08-years old, and 47 age- and gender-matched lean controls were studied. Anthropometric parameters, blood pressure, fasting oral glucose tolerance test, homeostatic model insulin resistance index (HOMA-IR), lipid profile, lipocalin-2, and A-FABP were evaluated. Weight loss was considered ifz-score body mass index (BMI) decreased at least 0.5s.d.ResultsAt baseline, lipocalin-2 and A-FABP were higher in prepubertal obese children than those in lean controls (P<0.001). A-FABP showed a gradual increase, according to the obesity degree (r2=0.632;P<0.001). After 2 years, obese patients who lost weight showed a decrease in A-FABP (a mean 2% reduction in BMI was associated with a mean 29% decrease in A-FABP (P<0.001)) without changes in lipocalin-2 levels. Regression model analysis adjusted by age, sex, BMI, and HOMA showed that A-FABP was lower in males (β=−5.77 (CI 95%: −9.7; −1.84)) and was modified by BMI (β=2.7 (CI 95%: 1.77–3.62),r2=0.659). Lipocalin-2 was not modified by any of these variables.ConclusionsPrepubertal obese children show high plasma lipocalin-2 and A-FABP levels, but only A-FABP is influenced by weight loss.

scholarly journals The Ala54Thr polymorphism of the fatty acid–binding protein 2 gene is associated with a change in insulin sensitivity after a change in the type of dietary fat

2005 ◽  
Vol 82 (1) ◽  
pp. 196-200 ◽  
Author(s):  
Carmen Marín ◽  
Francisco Pérez-Jiménez ◽  
Purificación Gómez ◽  
Javier Delgado ◽  
Juan Antonio Paniagua ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Insulin Sensitivity ◽  
Dietary Fat ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals High Dietary Fat Exacerbates Weight Gain and Obesity in Female Liver Fatty Acid Binding Protein Gene-Ablated Mice

Lipids ◽  
2009 ◽  
Vol 45 (2) ◽  
pp. 97-110 ◽  
Author(s):  
Barbara P. Atshaves ◽  
Avery L. McIntosh ◽  
Stephen M. Storey ◽  
Kerstin K. Landrock ◽  
Ann B. Kier ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Weight Gain ◽  
Dietary Fat ◽  
Fatty Acid Binding Protein ◽  
Protein Gene ◽  
Binding Protein ◽  
Liver Fatty Acid ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Binding Protein Gene

scholarly journals The Ala54Thr polymorphism of the fatty acid–binding protein 2 gene is associated with a change in insulin sensitivity after a change in the type of dietary fat

2005 ◽  
Vol 82 (1) ◽  
pp. 196-200 ◽  
Author(s):  
Carmen Marín ◽  
Francisco Pérez-Jiménez ◽  
Purificación Gómez ◽  
Javier Delgado ◽  
Juan Antonio Paniagua ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Insulin Sensitivity ◽  
Dietary Fat ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals Effects of an Ala54Thr polymorphism in the intestinal fatty acid-binding protein on responses to dietary fat in humans

2000 ◽  
Vol 41 (12) ◽  
pp. 2002-2008 ◽  
Author(s):  
R.E. Pratley ◽  
L. Baier ◽  
D.A. Pan ◽  
A.D. Salbe ◽  
L. Storlien ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Dietary Fat ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein
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