scholarly journals Changes in serum uric acid have a reciprocal effect on eGFR change: a 10-year follow-up study of community-based screening in Okinawa, Japan

2013 ◽  
Vol 36 (7) ◽  
pp. 650-654 ◽  
Author(s):  
Kunitoshi Iseki ◽  
Chiho Iseki ◽  
Kozen Kinjo
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Community Based ◽  
Reciprocal Effect ◽  
Follow Up Study

Lower serum uric acid is associated with mild cognitive impairment in early Parkinson’s disease: a 4-year follow-up study

2016 ◽  
Vol 123 (12) ◽  
pp. 1399-1402 ◽  
Author(s):  
Maria Teresa Pellecchia ◽  
Riccardo Savastano ◽  
Marcello Moccia ◽  
Marina Picillo ◽  
Pietro Siano ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Uric Acid ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Serum Uric Acid ◽  
Lower Serum ◽  
Follow Up Study ◽  
Early Parkinson’S Disease

scholarly journals AB0926 PERFORMANCE OF THE ACR-EULAR GOUT CLASSIFICATION CRITERIA FOR THE DIAGNOSIS GOUT IN CLINICAL PRACTICE: A ONE-YEAR FOLLOW-UP STUDY

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1763.1-1764
Author(s):  
M. Gamala ◽  
J. W. G. Jacobs ◽  
S. Linn-Rasker ◽  
M. Nix ◽  
B. Heggelman ◽  
...  
Keyword(s):  
Uric Acid ◽  
Clinical Practice ◽  
Serum Uric Acid ◽  
Dual Energy ◽  
Classification Criteria ◽  
Dual Energy Ct ◽  
Research Support ◽  
Follow Up Study ◽  
One Year

Background:Classification criteria are used for classifying groups of patients, especially for clinical trials, and diagnostic criteria for diagnosis in individual patients.Objectives:to establish the performance of the 2015 ACR/EULAR gout classification criteria for the diagnosis gout in patients with undifferentiated arthritis. Secondary, to explore the use and efficacy of uric acid lowering therapy (ULT) in daily clinical practice in new gout patients.Methods:1-year follow-up study was performed in subjects with unclassified arthritis, who had been classified as gout patients or not, according the gout classification criteria, including imaging with dual-energy CT, but without ultrasonography and joint X-rays.(1) The reference was the clinical diagnosis (gout yes/no) after 1-year follow-up.Results:71 patients were included; their demographic and clinical characteristics are summarized in Table 1. All 63/71 patients classified as having gout at baseline also had a clinical gout diagnosis after one year, and of the patients not classified, none had the clinical diagnosis of gout at one year.Table 1.Characteristics of the 71subjects included in analysesDiagnosis**gout (n=63)no gout (n=8)Age in years, mean (SD)62 (14)59 (14)Male gender, N (%)53 (84)5 (63)Symptom duration* at baseline in months, median (IQR)12 (1-48)8 (0.5-33)Joint involvement at baseline N patients (%):MTP,33 (52)1 (12)ankle/midfoot12 (19)1 (12)other joint18 (29)6 (76)SUA intercritical in umol/l, mean (SD)484 (63)337 (71)2015 ACR/EULAR criteria baseline score, mean (SD)***10.3 (2.5)2.6 (1.5)2015 ACR/EULAR criteria ≥8 points, N patients (%)***57 (90)0 (0)MSU crystal positive joint aspiration, N patients (%)44 (70)0 (0)DECT positive, N patients (%)49 (78)0 (0)* self-reported, intermittent symptoms; ** all patients classified with gout at baseline also had a clinical gout diagnosis after one yea; *** using a somewhat limited set, see methodsMTP, metatarsophalangeal joints; SUA, serum uric acid; DECT, dual-energy CT; MSU, monosodium urate;.Sensitivity, specificity, positive and negative predictive value, and accuracy values (95% CI) of the classification criteria set we used were 0.91 (0.80-0.96); 1 (0.63-1); 1; 0.57 (0.38-0.74) and 0.92 (0.83-0.97), respectively. The area under the receiver operating characteristics curve (95% CI) was 0.95 (0.91-0.99).ULT was started in 49/63 (78%) of gout patients; 45/49 (92%) of them had serum uric acid levels ≤ 360 μmol/l and no recurrent gout attack during one-year follow-up.Conclusion:The 2015 ACR-EULAR gout classification criteria performed well for the diagnosis gout in clinical practice. Most gout patients had been treated successfully, according to current guidelines.References:[1]Gamala M, Jacobs JWG, Linn-Rasker SF, Nix M, Heggelman BGF, Pasker-de Jong PCM, et al. The performance of dual-energy CT in the classification criteria of gout: a prospective study in subjects with unclassified arthritis. Rheumatology 2019 Sep (Epub ahead print).Disclosure of Interests:Mihaela Gamala: None declared, Johannes W. G. Jacobs Grant/research support from: Roche, Suzanne Linn-Rasker: None declared, Maarten Nix: None declared, Ben Heggelman: None declared, Pieternel Pasker: None declared, Jacob M. van Laar Grant/research support from: MSD, Genentech, Consultant of: MSD, Roche, Pfizer, Eli Lilly, BMS, Ruth Klaasen: None declared

scholarly journals Elevated Serum Uric Acid is Associated with Rapid Decline in Kidney Function: A 10-Year Follow-Up Study

2020 ◽  
Vol Volume 13 ◽  
pp. 945-953
Author(s):  
Kittrawee Kritmetapak ◽  
Suranut Charoensri ◽  
Rattrai Thaopanya ◽  
Chatlert Pongchaiyakul
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Kidney Function ◽  
Elevated Serum ◽  
Rapid Decline ◽  
Follow Up Study

Serum uric acid is an independent predictor for all major forms of cardiovascular death in 28,613 elderly women: A prospective 21-year follow-up study

2008 ◽  
Vol 125 (2) ◽  
pp. 232-239 ◽  
Author(s):  
Alexander M. Strasak ◽  
Cecily C. Kelleher ◽  
Larry J. Brant ◽  
Kilian Rapp ◽  
Elfriede Ruttmann ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Elderly Women ◽  
Independent Predictor ◽  
Cardiovascular Death ◽  
Follow Up Study
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